Understanding Physico-chemical Interactions of Dendrimers with Guest Molecules for Efficient Drug and Gene Delivery

2021 ◽  
Author(s):  
Aishwarya Shetty ◽  
Priyal Chikhaliwala ◽  
Jui Suryawanshi ◽  
Sudeshna Chandra
Keyword(s):  
Gene Delivery ◽  
Chemical Interactions ◽  
Guest Molecules ◽  
Physico Chemical ◽  
Drug And Gene Delivery

Cyclodextrins and their Derivatives as Carrier Molecules in Drug and Gene Delivery Systems

2019 ◽  
Vol 23 (11) ◽  
pp. 1256-1269 ◽  
Author(s):  
Ramin Karimian ◽  
Milad Aghajani
Keyword(s):  
Gene Delivery ◽  
Aqueous Solubility ◽  
Delivery Systems ◽  
Complexing Agents ◽  
Routes Of Administration ◽  
Naturally Occurring ◽  
Physico Chemical ◽  
Recent Developments ◽  
Major Emphasis ◽  
Drug And Gene Delivery

Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides containing six (α-CD), seven (β-CD), eight (γ-CD) and more glucopyranose units linked with α-(1,4) bonds, having a terminal hydrophilic part and central lipophilic cavity. α-, β- and γ-CDs are widely used in many industrial products, technologies and analytical methods owing to their unique, versatile and tunable characteristics. In the pharmaceutical industry, CDs are used as complexing agents to enhance aqueous solubility, physico-chemical stability and bio-availability of administered drugs. Herein, special attention is given to the use of α-, β- and γ-CDs and their derivatives in different areas of drug and gene delivery systems in the past few decades through various routes of administration with a major emphasis on the more recent developments.

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

Redox-Sensitive Smart Nanosystems for Drug and Gene Delivery

2016 ◽  
Vol 20 (28) ◽  
pp. 2949-2959 ◽  
Author(s):  
Mahdi Karimi ◽  
Seyed Basri ◽  
Manouchehr Vossoughi ◽  
Parvin Pakchin ◽  
Hamed Mirshekari ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Drug And Gene Delivery

On physico-chemical interactions between daunomycin and nucleic acids

1965 ◽  
Vol 103 (1) ◽  
pp. 25-49 ◽  
Author(s):  
E. Calendi ◽  
A. Di Marco ◽  
M. Reggiani ◽  
B. Scarpinato ◽  
L. Valentini
Keyword(s):  
Nucleic Acids ◽  
Chemical Interactions ◽  
Physico Chemical

scholarly journals Recent Advances of Nanotechnology-Facilitated Bacteria-Based Drug and Gene Delivery Systems for Cancer Treatment

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 940
Author(s):  
Chaojie Zhu ◽  
Zhiheng Ji ◽  
Junkai Ma ◽  
Zhijie Ding ◽  
Jie Shen ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cancer Treatment ◽  
Delivery Systems ◽  
Cancer Targeting ◽  
Cancer Treatments ◽  
Recent Advances ◽  
Therapeutic Mechanisms ◽  
Bacterial Therapy ◽  
Targeting Ability ◽  
Drug And Gene Delivery

Cancer is one of the most devastating and ubiquitous human diseases. Conventional therapies like chemotherapy and radiotherapy are the most widely used cancer treatments. Despite the notable therapeutic improvements that these measures achieve, disappointing therapeutic outcome and cancer reoccurrence commonly following these therapies demonstrate the need for better alternatives. Among them, bacterial therapy has proven to be effective in its intrinsic cancer targeting ability and various therapeutic mechanisms that can be further bolstered by nanotechnology. In this review, we will discuss recent advances of nanotechnology-facilitated bacteria-based drug and gene delivery systems in cancer treatment. Therapeutic mechanisms of these hybrid nanoformulations are highlighted to provide an up-to-date understanding of this emerging field.

Development of self-assembling peptide nanovesicle with bilayers for enhanced EGFR-targeted drug and gene delivery

Biomaterials ◽  
2016 ◽  
Vol 82 ◽  
pp. 194-207 ◽  
Author(s):  
Xiaofei Liang ◽  
Bizhi Shi ◽  
Kai Wang ◽  
Mingliang Fan ◽  
Dejin Jiao ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Self Assembling ◽  
Targeted Drug ◽  
Drug And Gene Delivery
Sign in / Sign up

Export Citation Format

Share Document