Ringer's-lactate

2021 ◽  
Vol 1867 (1) ◽  
pp. 360-360
Keyword(s):  
Ringer’S Lactate

scholarly journals Evaluation of Stroke Volume Variation Obtained by the FloTrac™/Vigileo™ System to Guide Preoperative Fluid Therapy in Patients Undergoing Brain Surgery

2012 ◽  
Vol 40 (3) ◽  
pp. 1175-1181 ◽  
Author(s):  
J Li ◽  
Fh Ji ◽  
Jp Yang
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Stroke Volume ◽  
Stroke Volume Variation ◽  
Brain Surgery ◽  
Fluid Loading ◽  
Volume Loading ◽  
Fluid Infusion ◽  
Volume Variation ◽  
Ringer’S Lactate

OBJECTIVE: The accuracy of stroke volume variation (SVV) obtained by the FloTrac™/Vigileo™ system in otherwise healthy patients undergoing brain surgery was assessed. METHODS: Anaesthesia was induced in 48 patients with minimal fluid infusion. Before surgery, fluid volume loading was performed by infusion with Ringer's lactate solution in 200 ml steps over 3 min, repeated successively if the patient responded with an increase in stroke volume of ≥ 10%, until the increase was < 10% (nonresponsive). RESULTS: A total of 157 volume loading steps were performed in the 48 patients. Responsive and nonresponsive steps differed significantly in baseline values of blood pressure, heart rate and SVV. Significant correlations were found between the change in stroke volume after fluid loading and values of blood pressure, heart rate and SVV before fluid loading, with SVV the most sensitive variable. CONCLUSION: Stroke volume variation obtained using the FloTrac™/Vigileo™ system is a sensitive predictor of fluid responsiveness in healthy patients before brain surgery.

scholarly journals Intraoperative Assessment of Fluid Responsiveness in Normotensive Dogs under Isoflurane Anaesthesia

2021 ◽  
Vol 8 (2) ◽  
pp. 26
Author(s):  
Despoina Skouropoulou ◽  
Luca Lacitignola ◽  
Caterina Di Bella ◽  
Marzia Stabile ◽  
Claudia Acquafredda ◽  
...  
Keyword(s):  
Fluid Responsiveness ◽  
Systolic Pressure ◽  
Fluid Challenge ◽  
Pressure Variation ◽  
Before And After ◽  
Ringer’S Lactate ◽  
Controlled Mechanical Ventilation ◽  
Variability Index ◽  
Plethysmographic Variability Index ◽  
Volume Controlled

The aim of this study was to evaluate the incidence of fluid responsiveness (FR) to a fluid challenge (FC) in normotensive dogs under anaesthesia. The accuracy of pulse pressure variation (PPV), systolic pressure variation (SPV), stroke volume variation (SVV), and plethysmographic variability index (PVI) for predicting FR was also evaluated. Dogs were anaesthetised with methadone, propofol, and inhaled isoflurane in oxygen, under volume-controlled mechanical ventilation. FC was performed by the administration of 5 mL/kg of Ringer’s lactate within 5 min. Cardiac index (CI; L/min/m2), PPV, (%), SVV (%), SPV (%), and PVI (%) were registered before and after FC. Data were analysed with ANOVA and ROC tests (p < 0.05). Fluid responsiveness was defined as 15% increase in CI. Eighty dogs completed the study. Fifty (62.5%) were responders and 30 (37.5%) were nonresponders. The PPV, PVI, SPV, and SVV cut-off values (AUC, p) for discriminating responders from nonresponders were PPV >13.8% (0.979, <0.001), PVI >14% (0.956, <0.001), SPV >4.1% (0.793, <0.001), and SVV >14.7% (0.729, <0.001), respectively. Up to 62.5% of normotensive dogs under inhalant anaesthesia may be fluid responders. PPV and PVI have better diagnostic accuracy to predict FR, compared to SPV and SVV.

scholarly journals New insights in prevention and treatment of sepsis-induced acute kidney injury

2013 ◽  
Vol 1 (1) ◽  
pp. 23-27
Author(s):  
Patrick M. Honore ◽  
Rita Jacobs ◽  
Olivier Joannes-Boyau ◽  
Willem Boer ◽  
Elisabeth De Waele ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Lactate Clearance ◽  
Trauma Patients ◽  
Abdominal Hypertension ◽  
Prevention And Treatment ◽  
Ringer’S Lactate ◽  
Important Challenge ◽  
Crystalloid Solutions ◽  
Renal Doppler

AbstractSepsis-induced acute kidney injury (SAKI) remains an important challenge for intensive care unit clinicians. We reviewed current available evidence regarding prevention and treatment of SAKI thereby incorporating some major recent advances and developments. Prevention includes early and ample administration of “balanced” crystalloid solutions such as Ringer’s lactate. For monitoring of renal function during resuscitation, lactate clearance rate is preferred above ScvO2or renal Doppler. Aiming at high central venous pressures seems to be deleterious in light of the novel “kidney afterload” concept. Noradrenaline is the vasopressor of choice for preventing SAKI. Intra-abdominal hypertension, a potent trigger of acute kidney injury in postoperative and trauma patients, should not be neglected in sepsis. Renal replacement therapy (RRT) must be started early in fluid-overloaded patients refractory to diuretics. Continuous RRT (CRRT) is the preferred modality in hemodynamically unstable SAKI but its use in more stable SAKI is increasing. In the absence of hypervolemia, diuretics should be avoided. Antimicrobial dosing during CRRT needs to be thoroughly reconsidered to assure adequate infection control.

ANTIBIOTIC STABILITY IN SOLUTIONS USED FOR INTRAVENOUS NUTRITION AND FLUID THERAPY

PEDIATRICS ◽  
1973 ◽  
Vol 51 (6) ◽  
pp. 1016-1026
Author(s):  
Ralph D. Feigin ◽  
Kanneth S. Moss ◽  
Penelope G. Shackelford
Keyword(s):  
Antimicrobial Activity ◽  
Normal Saline ◽  
Protein Hydrolysate ◽  
Significant Degree ◽  
Significant Loss ◽  
All Solutions ◽  
Ringer’S Lactate ◽  
Series Of Experiments ◽  
The Stability ◽  
Crystalline Amino Acids

The present study was designed to assess the stability of ampicillin, carbenicillin, clindamycin, kanamycin, cephalothin, methicillin, and penicillin in three parenteral hyperalimentation mixtures as reconstituted for delivery to the patient in the clinical setting. Stability at 4C, 25C, and 37C was tested in parenteral hyperalimentation mixtures containing either crystalline amino acids or a protein hydrolysate. In two series of experiments the stability at 4C, 25C, and 37C of ampicillin, cephalothin, and kanamycin also was assessed in Isolyte M (ISO M), Isolyte P (ISO P), Ringer's lactate (LR), 5% dextrose in water, (D5W), 10% dextrose in water (D1OW), dextrose in normal saline (D5S), and normal saline (NS) to which hydrocortisone or heparin had been added. All antibiotics retained their effectiveness at an acceptable level in the hyperalimentation solutions at 4C. At 25C and 37C, all antibiotics except clindamycin lost activity by 24 hours. Kanamycin was least stable in these solutions and ampicillin also lost a significant degree of antimicrobial activity. Addition of heparin or hydrocortisone imparted stability to ampicillin in the seven parenteral solutions although significant loss of activity was noted at 37C in D5W, D1OW, D5S, and LR. Most solutions containing heparin or hydrocortisone and cephalothin turned yellow by 24 hours. A precipitate appeared in solutions containing heparin and kanamycin but there was minimal loss of antimicrobial activity. Kanamycin was stable in all solutions containing hydrocortisone except in D5W and D10W at 37C.

Molecular weight of Hydroxyethyl Starch Molecules influences Coagulation Profile measured by thrombelastography

2008 ◽  
Vol 94 (1) ◽  
pp. 7-13
Author(s):  
M Felfernig ◽  
S Virmani ◽  
M Weintraud ◽  
U Oberndorfer ◽  
M Zimpfer ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Hydroxyethyl Starch ◽  
Platelet Activating Factor ◽  
Maximum Amplitude ◽  
Coagulation System ◽  
Trauma Patients ◽  
Platelet Activity ◽  
Ringer’S Lactate ◽  
Plasmatic Coagulation ◽  
Key Words Coagulation

SummaryBackgroundThe consensus about the ideal intravenous fluid in trauma patients remains open. However, hypertonic saline and hydroxyethyl starch (HES) seems to have advantages in terms of immuno-modulatory and haemodynamic effects. Nevertheless clotting abnormalities are frequently reported in association with the use of HES. We investigated the influence of light, medium and heavy molecular weight (MW) hydroxyethyl starch (HES) on coagulation in 29 healthy subjects.MethodsRinger’s lactate (RL) served as a control solution. Thrombelastography using Haemoscope’s Thrombelastograph® (TEG®) hemostasis system was used to assess the effect of HES polymers and RL. TEG analysis was performed using recalcified native whole blood both with and without the addition of platelet activating factor IV (PAF IV) before and immediately after infusion of one of the solutions.ResultsInfusion of RL or one of the three HES solutions exerts an anticoagulant effect as demonstrated by a increase in clot formation time (R) and a decrease in maximum amplitude (MA), and the angle. The addition of PAF IV reversed these changes.ConclusionsThis data indicate clear evidence of platelet activity per se or platelet interaction with the plasmatic coagulation system. Key words: Coagulation, thrombelastography, platelets, hydroxyethyl-starch

scholarly journals Population-based volume kinetics of Ringer’s lactate solution in patients undergoing open gastrectomy

2018 ◽  
Vol 40 (5) ◽  
pp. 710-716 ◽  
Author(s):  
Joo-Hyun Lee ◽  
Yeong-Jin Choo ◽  
Yong-Hun Lee ◽  
Jin-Ho Rhim ◽  
Soo-Han Lee ◽  
...  
Keyword(s):  
Population Based ◽  
Open Gastrectomy ◽  
Ringer’S Lactate ◽  
Volume Kinetics ◽  
Kinetics Of ◽  
Lactate Solution

scholarly journals The effect of Ringer’s acetate versus Ringer’s lactate on aminotransferase changes in dengue hemorrhagic fever

2016 ◽  
Vol 45 (2) ◽  
pp. 81
Author(s):  
Mulya Rahma Karyanti ◽  
Hindra Irawan Satari ◽  
Damayanti Rusli Sjarif
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Prior Treatment ◽  
Aminotransferase Level ◽  
Inclusion Criteria ◽  
Double Blind ◽  
Ringer’S Lactate ◽  
To Receive

Background Dengue hemorrhagic fever (DHF) infection causeshepatocelullar impairment. In management of DHF, World HealthOrganization (WHO) recommends the crystalloids Ringer’s acetate(RA) or Ringer’s lactate (RL), which are similar in composition toplasma. Acetate in RA is not metabolized in the liver, hence notburdening the liver, whereas lactate in RL is metabolized mostly inthe liver, thus placing a burden on the liver.Objective To compare aminotransferase changes as markers ofhepatocellular impairment subsequent to the use of RA and RL inthe management of DHF with and without shock.Methods This study was a double-blind randomized controlledtrial on DHF patients aged 1-18 years in Cipto MangunkusumoHospital who had not received prior treatment with crystalloids orcolloids. Subjects were randomly assigned to receive either RA orRL intravenously. Aminotransferase levels were examined on thefirst, second and third weeks from the onset of fever.Results Ninety-two patients who fulfilled inclusion criteria wereenrolled in this study, consisting of those without and with shock.Mean transaminase levels of patients without shock in the RA andRL groups did not differ significantly. Mean transaminase levels ofpatients with shock in the RA group were lower than those in theRL group, but this difference was not significant statistically. Meanalteration of transaminase levels in patients with and without shockwere not significantly different.Conclusion In DHF without shock, there is no significant differ-ence between aminotransferase level changes of patients receiv-ing RA and RL solutions. In DHF with shock, aminotransferaselevels of patients receiving RA tend to be lower than those receiv-ing RL, but this difference is insignificant

Hartmann's solution and Ringer's lactate: targeting the fourth space

2002 ◽  
Vol 104 (1) ◽  
pp. 25-26
Author(s):  
NICHOLAS J. WILKES
Keyword(s):  
Ringer’S Lactate
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