Association of thyroid cancer risk with plasma 25-hydroxyvitamin D and vitamin D binding protein: a case–control study in China

2019 ◽  
Vol 43 (6) ◽  
pp. 799-808
Author(s):  
M.-J. Hu ◽  
Q.-S. Niu ◽  
H.-B. Wu ◽  
X.-L. Lu ◽  
L. Wang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Thyroid Cancer ◽  
Case Control Study ◽  
Protein A ◽  
Case Control ◽  
Vitamin D Binding Protein ◽  
Hydroxyvitamin D ◽  
Thyroid Cancer Risk ◽  
25 Hydroxyvitamin D ◽  
Control Study

scholarly journals Impact of Circulating Vitamin D Binding Protein Levels on the Association between 25-Hydroxyvitamin D and Pancreatic Cancer Risk: A Nested Case–Control Study

2012 ◽  
Vol 72 (5) ◽  
pp. 1190-1198 ◽  
Author(s):  
Stephanie J. Weinstein ◽  
Rachael Z. Stolzenberg-Solomon ◽  
William Kopp ◽  
Helen Rager ◽  
Jarmo Virtamo ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Vitamin D ◽  
Case Control Study ◽  
Case Control ◽  
Vitamin D Binding Protein ◽  
Hydroxyvitamin D ◽  
Protein Levels ◽  
25 Hydroxyvitamin D ◽  
Nested Case Control ◽  
Control Study

scholarly journals Circulating vitamin D–binding protein and free 25-hydroxyvitamin D concentrations in patients with melanoma: A case-control study

2017 ◽  
Vol 77 (3) ◽  
pp. 575-577 ◽  
Author(s):  
Cristián Navarrete-Dechent ◽  
Constanza del Puerto ◽  
Montserrat Molgó ◽  
Sergio González ◽  
Guillermo Pérez-Mateluna ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Binding Protein ◽  
Case Control ◽  
Vitamin D Binding Protein ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Control Study

scholarly journals Serum 25-hydroxyvitamin D level in psoriasis patients: a case-control study

2019 ◽  
Vol 5 (1) ◽  
pp. 27
Author(s):  
Surinder Gupta ◽  
Preeti Garg ◽  
Nakul Gupta
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Treatment Resistance ◽  
Case Control ◽  
The Body ◽  
North India ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Differentiation And Proliferation ◽  
Control Study

<p class="abstract"><strong>Background:</strong> Sufficient level of vitamin D in blood is required for proper regulation of cell differentiation and proliferation. Unchecked proliferation of cells leads to various disease states. Vitamin D also has immunomodulatory effects in the body. Psoriasis is a chronic inflammatory and hyperproliferative disease with vitamin D having an impact on it. This case – control study was done to judge the levels of vitamin D in patients of psoriasis compared to age and sex matched controls.</p><p class="abstract"><strong>Methods:</strong> A case control study was conducted including 50 patients (35 females and 15 males) of chronic plaque psoriasis from dermatology outpatient department of Maharaja Agrasen Medical College (MAMC), Agroha, Haryana, representing patients from north India and 50 healthy controls. Both urban and rural background patients were included.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean serum 25-hydroxyvitamin D (25-OHD) level in psoriasis patients was 22.865±11.386 ng/ml, whereas in controls it was 35.116±11.048 ng/ml (p&lt;0.001). Serum level of 25-OHD in psoriatic patients was deficient (&lt;20 ng/ml) in 26 (52%), insufficient (20-30 ng/ml) in 8 (16%) psoriatic patients.</p><p class="abstract"><strong>Conclusions:</strong> High prevalence of low vitamin D level was found in this study. We infer that vitamin D does play a role in the pathogenesis, precipitation, exacerbation, or treatment resistance of psoriasis.</p><p> </p>

scholarly journals Serum 25-hydroxyvitamin D level and vitamin D receptor (VDR) polymorphisms in patients infected with Leishmania tropica: a case control study

2019 ◽  
Vol 44 (1) ◽  
pp. 40-48
Author(s):  
Hajar Shabandoust ◽  
Iraj Sharifi ◽  
Omid Raiesi ◽  
Muhammad Ibrahim Getso ◽  
Ebrahim Dezaki Saedi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Case Control Study ◽  
Case Control ◽  
Leishmania Tropica ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Control Study ◽  
Vdr Polymorphisms

scholarly journals Serum Levels of 25-Hydroxyvitamin D in Patients with Seborrheic Dermatitis: A Case-Control Study

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Siavash Rahimi ◽  
Negar Nemati ◽  
Seyedeh Sareh Shafaei-Tonekaboni
Keyword(s):  
Vitamin D ◽  
Healthy Subjects ◽  
Case Control Study ◽  
Seborrheic Dermatitis ◽  
Case Control ◽  
Lower Serum ◽  
Hydroxyvitamin D ◽  
Control Subjects ◽  
25 Hydroxyvitamin D ◽  
Control Study

Several autoimmune papulosquamous skin conditions such as psoriasis, systemic lupus erythematous, and lichen planus have been associated with vitamin D deficiency or correlated with serum vitamin D level. This study was aimed at comparing the 25-hydroxyvitamin D (25(OH)D) status in patients with facial or scalp seborrheic dermatitis with healthy subjects. This case-control study included 289 patients (118 with psoriasis and 171 sex- and age-matched control subjects) from the outpatient clinic of two hospital dermatology departments in the west of Mazandaran province, Iran. All patients and control subjects were studied during one season to avoid seasonal variations in vitamin D levels. Serum mean ± standard deviation of 25(OH)D levels were significantly lower in seborrheic dermatitis patients than in control subjects (20.71 ± 8.16 vs. 23.91 ± 7.78, P  = 0.007). Serum 25(OH)D levels were negatively associated with the risk of developing seborrheic dermatitis (odds ratio (OR): 0.898, 95% confidence interval (Cl): 0.840–0.960, P  = 0.002). Also, vitamin D under 30 ng/ml was associated with OR: 4.22 (95% Cl: 1.077–16.534, P  = 0.039) for seborrheic dermatitis. The severity of scalp disease was significantly associated with serum 25(OH)D level ( P  = 0.003). Cases with severe scalp scores had significantly lower serum 25(OH)D level compared to moderate OR score ( P  = 0.036). A similar trend was not seen in the facial disease. The 25(OH)D values are significantly lower in seborrheic dermatitis patients than in healthy subjects. Furthermore, the scalp disease severity was associated with lower serum 25(OH)D level. Our results may suggest that vitamin D may play a role in the pathogenesis of seborrheic dermatitis.

Serum 25-hydroxyvitamin D status in chinese children with vitiligo: a case-control study

2017 ◽  
Vol 57 (7) ◽  
pp. 802-805 ◽  
Author(s):  
Xianhui Zhang ◽  
Wei Wang ◽  
Yuanjun Li ◽  
Hui Wang ◽  
Runtao Liu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Family History ◽  
Autoimmune Diseases ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
25 Hydroxyvitamin D ◽  
Control Study

Background. Vitamin D can play a vital role in autoimmune diseases. Epidemiologic evidence demonstrates vitamin D deficiency excited in adult patients with vitiligo. Objectives. To investigate 25-hydroxyvitamin D (25(OH)D) levels in children with vitiligo and explore possible relevant factors. Methods. A total of 114 patients and 100 controls were included in our case-control study. We analyzed the required data collected by the questionnaire and examination to reveal the correlation with 25(OH)D levels. Results. The mean serum 25(OH)D levels in patients and controls were 43.62 ± 19.23 and 67.87 ± 19.45 nmol/L, respectively. The rate of deficient in patients and controls are 14.9% and 2%, respectively. There was significant difference between the 2 groups. Significant differences also existed on different ages comparing serum vitamin D levels of patients with controls ( P < .001). Age was an independent factor affecting 25(OH)D level ( P = .032). Two (1.8%) and 4 (3.5%) of children with vitiligo have comorbid autoimmune diseases and family history, respectively. There was no correlation between sex, duration of disease, type of vitiligo, skin lesion location, stage, family history, and comorbid autoimmune diseases with 25(OH)D levels. Conclusion. Serum vitamin D level was associated with onset vitiligo children. More sunshine and vitamin D fortified foods are necessary among children with age. The rates of children vitiligo with family history has decreased in China.

scholarly journals Serum 25-hydroxyvitamin D, serum calcium and vitamin D receptor (VDR) polymorphisms in a selected population with lumbar disc herniation—A case control study

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205841 ◽  
Author(s):  
Niroshima Dedunu Withanage ◽  
Sunil Perera ◽  
Hemantha Peiris ◽  
Lohini Vijayendran Athiththan
Keyword(s):  
Vitamin D ◽  
Serum Calcium ◽  
Vitamin D Receptor ◽  
Case Control Study ◽  
Lumbar Disc ◽  
Case Control ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Control Study ◽  
Vdr Polymorphisms

scholarly journals The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng Wang ◽  
Wei-Wei Gong ◽  
Feng Lu ◽  
Ru-Ying Hu ◽  
Qing-Fang He ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Case Control Study ◽  
Positive Family History ◽  
Case Control ◽  
Diabetes Duration ◽  
Family History Of Diabetes ◽  
Thyroid Cancer Risk ◽  
History Of ◽  
Control Study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

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