scholarly journals A deep network designed for segmentation and classification of leukemia using fusion of the transfer learning models

2021 ◽  
Author(s):  
Saba Saleem ◽  
Javeria Amin ◽  
Muhammad Sharif ◽  
Muhammad Almas Anjum ◽  
Muhammad Iqbal ◽  
...  
Keyword(s):  
Early Stage ◽  
White Blood Cells ◽  
Principal Component ◽  
Semantic Segmentation ◽  
Morphological Operations ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Color Transformation ◽  
Global Accuracy

AbstractWhite blood cells (WBCs) are a portion of the immune system which fights against germs. Leukemia is the most common blood cancer which may lead to death. It occurs due to the production of a large number of immature WBCs in the bone marrow that destroy healthy cells. To overcome the severity of this disease, it is necessary to diagnose the shapes of immature cells at an early stage that ultimately reduces the modality rate of the patients. Recently different types of segmentation and classification methods are presented based upon deep-learning (DL) models but still have some limitations. This research aims to propose a modified DL approach for the accurate segmentation of leukocytes and their classification. The proposed technique includes two core steps: preprocessing-based classification and segmentation. In preprocessing, synthetic images are generated using a generative adversarial network (GAN) and normalized by color transformation. The optimal deep features are extracted from each blood smear image using pretrained deep models i.e., DarkNet-53 and ShuffleNet. More informative features are selected by principal component analysis (PCA) and fused serially for classification. The morphological operations based on color thresholding with the deep semantic method are utilized for leukemia segmentation of classified cells. The classification accuracy achieved with ALL-IDB and LISC dataset is 100% and 99.70% for the classification of leukocytes i.e., blast, no blast, basophils, neutrophils, eosinophils, lymphocytes, and monocytes, respectively. Whereas semantic segmentation achieved 99.10% and 98.60% for average and global accuracy, respectively. The proposed method achieved outstanding outcomes as compared to the latest existing research works.

scholarly journals Improved Classification of White Blood Cells with the Generative Adversarial Network and Deep Convolutional Neural Network

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Khaled Almezhghwi ◽  
Sertan Serte
Keyword(s):  
Blood Cells ◽  
Data Augmentation ◽  
White Blood Cells ◽  
Training Data ◽  
Generative Adversarial Networks ◽  
Generative Adversarial Network ◽  
Human Errors ◽  
Morphological Variations ◽  
Adversarial Network

White blood cells (leukocytes) are a very important component of the blood that forms the immune system, which is responsible for fighting foreign elements. The five types of white blood cells include neutrophils, eosinophils, lymphocytes, monocytes, and basophils, where each type constitutes a different proportion and performs specific functions. Being able to classify and, therefore, count these different constituents is critical for assessing the health of patients and infection risks. Generally, laboratory experiments are used for determining the type of a white blood cell. The staining process and manual evaluation of acquired images under the microscope are tedious and subject to human errors. Moreover, a major challenge is the unavailability of training data that cover the morphological variations of white blood cells so that trained classifiers can generalize well. As such, this paper investigates image transformation operations and generative adversarial networks (GAN) for data augmentation and state-of-the-art deep neural networks (i.e., VGG-16, ResNet, and DenseNet) for the classification of white blood cells into the five types. Furthermore, we explore initializing the DNNs’ weights randomly or using weights pretrained on the CIFAR-100 dataset. In contrast to other works that require advanced image preprocessing and manual feature extraction before classification, our method works directly with the acquired images. The results of extensive experiments show that the proposed method can successfully classify white blood cells. The best DNN model, DenseNet-169, yields a validation accuracy of 98.8%. Particularly, we find that the proposed approach outperforms other methods that rely on sophisticated image processing and manual feature engineering.

scholarly journals An Imbalanced Image Classification Method for the Cell Cycle Phase

Information ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 249
Author(s):  
Xin Jin ◽  
Yuanwen Zou ◽  
Zhongbing Huang
Keyword(s):  
Cell Cycle ◽  
Deep Learning ◽  
Image Classification ◽  
Classification Accuracy ◽  
Data Augmentation ◽  
Cycle Phase ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Cellular Life

The cell cycle is an important process in cellular life. In recent years, some image processing methods have been developed to determine the cell cycle stages of individual cells. However, in most of these methods, cells have to be segmented, and their features need to be extracted. During feature extraction, some important information may be lost, resulting in lower classification accuracy. Thus, we used a deep learning method to retain all cell features. In order to solve the problems surrounding insufficient numbers of original images and the imbalanced distribution of original images, we used the Wasserstein generative adversarial network-gradient penalty (WGAN-GP) for data augmentation. At the same time, a residual network (ResNet) was used for image classification. ResNet is one of the most used deep learning classification networks. The classification accuracy of cell cycle images was achieved more effectively with our method, reaching 83.88%. Compared with an accuracy of 79.40% in previous experiments, our accuracy increased by 4.48%. Another dataset was used to verify the effect of our model and, compared with the accuracy from previous results, our accuracy increased by 12.52%. The results showed that our new cell cycle image classification system based on WGAN-GP and ResNet is useful for the classification of imbalanced images. Moreover, our method could potentially solve the low classification accuracy in biomedical images caused by insufficient numbers of original images and the imbalanced distribution of original images.

scholarly journals Improving Road Semantic Segmentation Using Generative Adversarial Network

IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 64381-64392
Author(s):  
Abolfazl Abdollahi ◽  
Biswajeet Pradhan ◽  
Gaurav Sharma ◽  
Khairul Nizam Abdul Maulud ◽  
Abdullah Alamri
Keyword(s):  
Semantic Segmentation ◽  
Generative Adversarial Network ◽  
Adversarial Network

scholarly journals 1D conditional generative adversarial network for spectrum-to-spectrum translation of simulated chemical reflectance signatures

2021 ◽  
Author(s):  
Cara Murphy ◽  
John Kerekes
Keyword(s):  
Classification Accuracy ◽  
Domain Adaptation ◽  
Real Data ◽  
Training Set ◽  
Generative Adversarial Network ◽  
Average Classification Accuracy ◽  
Adversarial Network ◽  
Chemical Residues ◽  
Reflectance Data

The classification of trace chemical residues through active spectroscopic sensing is challenging due to the lack of physics-based models that can accurately predict spectra. To overcome this challenge, we leveraged the field of domain adaptation to translate data from the simulated to the measured domain for training a classifier. We developed the first 1D conditional generative adversarial network (GAN) to perform spectrum-to-spectrum translation of reflectance signatures. We applied the 1D conditional GAN to a library of simulated spectra and quantified the improvement in classification accuracy on real data using the translated spectra for training the classifier. Using the GAN-translated library, the average classification accuracy increased from 0.622 to 0.723 on real chemical reflectance data, including data from chemicals not included in the GAN training set.

FISS GAN: A Generative Adversarial Network for Foggy Image Semantic Segmentation

2021 ◽  
Vol 8 (8) ◽  
pp. 1428-1439
Author(s):  
Kunhua Liu ◽  
Zihao Ye ◽  
Hongyan Guo ◽  
Dongpu Cao ◽  
Long Chen ◽  
...  
Keyword(s):  
Semantic Segmentation ◽  
Generative Adversarial Network ◽  
Adversarial Network

scholarly journals Semantic Segmentation of White Matter in FDG-PET Using Generative Adversarial Network

2020 ◽  
Vol 33 (4) ◽  
pp. 816-825
Author(s):  
Kyeong Taek Oh ◽  
Sangwon Lee ◽  
Haeun Lee ◽  
Mijin Yun ◽  
Sun K. Yoo
Keyword(s):  
White Matter ◽  
Fdg Pet ◽  
Semantic Segmentation ◽  
Generative Adversarial Network ◽  
Adversarial Network

scholarly journals Separating Chinese Character from Noisy Background Using GAN

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Bin Huang ◽  
Jiaqi Lin ◽  
Jinming Liu ◽  
Jie Chen ◽  
Jiemin Zhang ◽  
...  
Keyword(s):  
Character Recognition ◽  
Optical Character Recognition ◽  
Complex Structure ◽  
Real Data ◽  
Semantic Segmentation ◽  
Chinese Characters ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Basic Network ◽  
Noisy Background

Separating printed or handwritten characters from a noisy background is valuable for many applications including test paper autoscoring. The complex structure of Chinese characters makes it difficult to obtain the goal because of easy loss of fine details and overall structure in reconstructed characters. This paper proposes a method for separating Chinese characters based on generative adversarial network (GAN). We used ESRGAN as the basic network structure and applied dilated convolution and a novel loss function that improve the quality of reconstructed characters. Four popular Chinese fonts (Hei, Song, Kai, and Imitation Song) on real data collection were tested, and the proposed design was compared with other semantic segmentation approaches. The experimental results showed that the proposed method effectively separates Chinese characters from noisy background. In particular, our methods achieve better results in terms of Intersection over Union (IoU) and optical character recognition (OCR) accuracy.

scholarly journals Detection and Classification of Early Stage Lesions in Diabetic Retinopathy using Color Fundus Images

2019 ◽  
Vol 8 (3) ◽  
pp. 4476-4480
Keyword(s):  
Diabetic Retinopathy ◽  
Clustering Algorithm ◽  
Early Stage ◽  
High Sensitivity ◽  
Morphological Operations ◽  
Hybrid Features ◽  
Speeded Up Robust Features ◽  
Fuzzy C Means Clustering ◽  
Color Fundus Images

Detection of lesions and classification of Diabetic Retinopathy (DR) play an important role in day-to-day life. In this proposed system, colour fundus image is pre-processed using morphological operations to recover from noises and it is converted into HSV colorspace. Fuzzy C-Means Clustering algorithm (FCMC) is used for segmenting the early stage lesions such as Microaneurysms (Ma), Haemorrhages (HE) and Exudates. Hybrid features such as colour correlogram and speeded up robust features (surf) are extracted to train the classifier. Cascaded Rotation Forest (CRF) classifier is used for classification of diabetic retinopathy. The proposed system increases the accuracy of detection and it has got high sensitivity.

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