scholarly journals An Imbalanced Image Classification Method for the Cell Cycle Phase

Information ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 249
Author(s):  
Xin Jin ◽  
Yuanwen Zou ◽  
Zhongbing Huang
Keyword(s):  
Cell Cycle ◽  
Deep Learning ◽  
Image Classification ◽  
Classification Accuracy ◽  
Data Augmentation ◽  
Cycle Phase ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Cellular Life

The cell cycle is an important process in cellular life. In recent years, some image processing methods have been developed to determine the cell cycle stages of individual cells. However, in most of these methods, cells have to be segmented, and their features need to be extracted. During feature extraction, some important information may be lost, resulting in lower classification accuracy. Thus, we used a deep learning method to retain all cell features. In order to solve the problems surrounding insufficient numbers of original images and the imbalanced distribution of original images, we used the Wasserstein generative adversarial network-gradient penalty (WGAN-GP) for data augmentation. At the same time, a residual network (ResNet) was used for image classification. ResNet is one of the most used deep learning classification networks. The classification accuracy of cell cycle images was achieved more effectively with our method, reaching 83.88%. Compared with an accuracy of 79.40% in previous experiments, our accuracy increased by 4.48%. Another dataset was used to verify the effect of our model and, compared with the accuracy from previous results, our accuracy increased by 12.52%. The results showed that our new cell cycle image classification system based on WGAN-GP and ResNet is useful for the classification of imbalanced images. Moreover, our method could potentially solve the low classification accuracy in biomedical images caused by insufficient numbers of original images and the imbalanced distribution of original images.

scholarly journals 1D conditional generative adversarial network for spectrum-to-spectrum translation of simulated chemical reflectance signatures

2021 ◽  
Author(s):  
Cara Murphy ◽  
John Kerekes
Keyword(s):  
Classification Accuracy ◽  
Domain Adaptation ◽  
Real Data ◽  
Training Set ◽  
Generative Adversarial Network ◽  
Average Classification Accuracy ◽  
Adversarial Network ◽  
Chemical Residues ◽  
Reflectance Data

The classification of trace chemical residues through active spectroscopic sensing is challenging due to the lack of physics-based models that can accurately predict spectra. To overcome this challenge, we leveraged the field of domain adaptation to translate data from the simulated to the measured domain for training a classifier. We developed the first 1D conditional generative adversarial network (GAN) to perform spectrum-to-spectrum translation of reflectance signatures. We applied the 1D conditional GAN to a library of simulated spectra and quantified the improvement in classification accuracy on real data using the translated spectra for training the classifier. Using the GAN-translated library, the average classification accuracy increased from 0.622 to 0.723 on real chemical reflectance data, including data from chemicals not included in the GAN training set.

scholarly journals Generating Natural Counterfactual Visual Explanations

2020 ◽  
Author(s):  
Wenqi Zhao ◽  
Satoshi Oyama ◽  
Masahito Kurihara
Keyword(s):  
Image Classification ◽  
Classification Accuracy ◽  
Classification Task ◽  
Learning Models ◽  
Generative Adversarial Network ◽  
Fine Grained ◽  
Class A ◽  
Adversarial Network ◽  
Class B ◽  
Machine Learning Models

Counterfactual explanations help users to understand the behaviors of machine learning models by changing the inputs for the existing outputs. For an image classification task, an example counterfactual visual explanation explains: "for an example that belongs to class A, what changes do we need to make to the input so that the output is more inclined to class B." Our research considers changing the attribute description text of class A on the basis of the attributes of class B and generating counterfactual images on the basis of the modified text. We can use the prediction results of the model on counterfactual images to find the attributes that have the greatest effect when the model is predicting classes A and B. We applied our method to a fine-grained image classification dataset and used the generative adversarial network to generate natural counterfactual visual explanations. To evaluate these explanations, we used them to assist crowdsourcing workers in an image classification task. We found that, within a specific range, they improved classification accuracy.

scholarly journals Improving Image-Based Plant Disease Classification With Generative Adversarial Network Under Limited Training Set

2020 ◽  
Vol 11 ◽  
Author(s):  
Luning Bi ◽  
Guiping Hu
Keyword(s):  
Classification Accuracy ◽  
Plant Disease ◽  
Data Augmentation ◽  
Plant Diseases ◽  
Disease Classification ◽  
Training Data ◽  
Training Dataset ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Overfitting Problem

Traditionally, plant disease recognition has mainly been done visually by human. It is often biased, time-consuming, and laborious. Machine learning methods based on plant leave images have been proposed to improve the disease recognition process. Convolutional neural networks (CNNs) have been adopted and proven to be very effective. Despite the good classification accuracy achieved by CNNs, the issue of limited training data remains. In most cases, the training dataset is often small due to significant effort in data collection and annotation. In this case, CNN methods tend to have the overfitting problem. In this paper, Wasserstein generative adversarial network with gradient penalty (WGAN-GP) is combined with label smoothing regularization (LSR) to improve the prediction accuracy and address the overfitting problem under limited training data. Experiments show that the proposed WGAN-GP enhanced classification method can improve the overall classification accuracy of plant diseases by 24.4% as compared to 20.2% using classic data augmentation and 22% using synthetic samples without LSR.

scholarly journals A Hybrid Capsule Network for Pneumonia Detection Using Image Augmentation Based on Generative Adversarial Network

2021 ◽  
Vol 38 (3) ◽  
pp. 619-627
Author(s):  
Kazim Firildak ◽  
Muhammed Fatih Talu
Keyword(s):  
Classification Accuracy ◽  
Data Augmentation ◽  
Model Parameters ◽  
Classification Problems ◽  
Generative Adversarial Network ◽  
X Ray ◽  
Discrimination Capability ◽  
Adversarial Network ◽  
Original Dataset ◽  
Chest X Ray

Pneumonia, featured by inflammation of the air sacs in one or both lungs, is usually detected by examining chest X-ray images. This paper probes into the classification models that can distinguish between normal and pneumonia images. As is known, trained networks like AlexNet and GoogleNet are deep network architectures, which are widely adopted to solve many classification problems. They have been adapted to the target datasets, and employed to classify new data generated through transfer learning. However, the classical architectures are not accurate enough for the diagnosis of pneumonia. Therefore, this paper designs a capsule network with high discrimination capability, and trains the network on Kaggle’s online pneumonia dataset, which contains chest X-ray images of many adults and children. The original dataset consists of 1,583 normal images, and 4,273 pneumonia images. Then, two data augmentation approaches were applied to the dataset, and their effects on classification accuracy were compared in details. The model parameters were optimized through five different experiments. The results show that the highest classification accuracy (93.91% even on small images) was achieved by the capsule network, coupled with data augmentation by generative adversarial network (GAN), using optimized parameters. This network outperformed the classical strategies.

scholarly journals Wildfire-Detection Method Using DenseNet and CycleGAN Data Augmentation-Based Remote Camera Imagery

2020 ◽  
Vol 12 (22) ◽  
pp. 3715 ◽  
Author(s):  
Minsoo Park ◽  
Dai Quoc Tran ◽  
Daekyo Jung ◽  
Seunghee Park
Keyword(s):  
Deep Learning ◽  
Data Augmentation ◽  
Model Performance ◽  
Image Data ◽  
Detection Accuracy ◽  
Generative Adversarial Network ◽  
Data Imbalance ◽  
Surveillance Camera ◽  
Convolutional Networks ◽  
Adversarial Network

To minimize the damage caused by wildfires, a deep learning-based wildfire-detection technology that extracts features and patterns from surveillance camera images was developed. However, many studies related to wildfire-image classification based on deep learning have highlighted the problem of data imbalance between wildfire-image data and forest-image data. This data imbalance causes model performance degradation. In this study, wildfire images were generated using a cycle-consistent generative adversarial network (CycleGAN) to eliminate data imbalances. In addition, a densely-connected-convolutional-networks-based (DenseNet-based) framework was proposed and its performance was compared with pre-trained models. While training with a train set containing an image generated by a GAN in the proposed DenseNet-based model, the best performance result value was realized among the models with an accuracy of 98.27% and an F1 score of 98.16, obtained using the test dataset. Finally, this trained model was applied to high-quality drone images of wildfires. The experimental results showed that the proposed framework demonstrated high wildfire-detection accuracy.

scholarly journals Robust classification of cell cycle phase and biological feature extraction by image-based deep learning

2020 ◽  
Vol 31 (13) ◽  
pp. 1346-1354 ◽  
Author(s):  
Yukiko Nagao ◽  
Mika Sakamoto ◽  
Takumi Chinen ◽  
Yasushi Okada ◽  
Daisuke Takao
Keyword(s):  
Neural Network ◽  
Cell Cycle ◽  
Feature Extraction ◽  
Deep Learning ◽  
Cell Cycle Phase ◽  
Data Driven ◽  
Cycle Phase ◽  
Biological Feature ◽  
Biological Features

By applying convolutional neural network-based classifiers, we demonstrate that cell images can be robustly classified according to cell cycle phases. Combined with Grad-CAM analysis, our approach enables us to extract biological features underlying cellular phenomena of interest in an unbiased and data-driven manner.

scholarly journals Improved Classification of White Blood Cells with the Generative Adversarial Network and Deep Convolutional Neural Network

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Khaled Almezhghwi ◽  
Sertan Serte
Keyword(s):  
Blood Cells ◽  
Data Augmentation ◽  
White Blood Cells ◽  
Training Data ◽  
Generative Adversarial Networks ◽  
Generative Adversarial Network ◽  
Human Errors ◽  
Morphological Variations ◽  
Adversarial Network

White blood cells (leukocytes) are a very important component of the blood that forms the immune system, which is responsible for fighting foreign elements. The five types of white blood cells include neutrophils, eosinophils, lymphocytes, monocytes, and basophils, where each type constitutes a different proportion and performs specific functions. Being able to classify and, therefore, count these different constituents is critical for assessing the health of patients and infection risks. Generally, laboratory experiments are used for determining the type of a white blood cell. The staining process and manual evaluation of acquired images under the microscope are tedious and subject to human errors. Moreover, a major challenge is the unavailability of training data that cover the morphological variations of white blood cells so that trained classifiers can generalize well. As such, this paper investigates image transformation operations and generative adversarial networks (GAN) for data augmentation and state-of-the-art deep neural networks (i.e., VGG-16, ResNet, and DenseNet) for the classification of white blood cells into the five types. Furthermore, we explore initializing the DNNs’ weights randomly or using weights pretrained on the CIFAR-100 dataset. In contrast to other works that require advanced image preprocessing and manual feature extraction before classification, our method works directly with the acquired images. The results of extensive experiments show that the proposed method can successfully classify white blood cells. The best DNN model, DenseNet-169, yields a validation accuracy of 98.8%. Particularly, we find that the proposed approach outperforms other methods that rely on sophisticated image processing and manual feature engineering.

scholarly journals Generative Adversarial Network for Class-Conditional Data Augmentation

2020 ◽  
Vol 10 (23) ◽  
pp. 8415
Author(s):  
Jeongmin Lee ◽  
Younkyoung Yoon ◽  
Junseok Kwon
Keyword(s):  
Classification Accuracy ◽  
Data Augmentation ◽  
Denoising Autoencoder ◽  
Generative Adversarial Network ◽  
Minority Class ◽  
Adversarial Network ◽  
Latent Space ◽  
Benchmark Datasets ◽  
Class Information ◽  
Classification Tasks

We propose a novel generative adversarial network for class-conditional data augmentation (i.e., GANDA) to mitigate data imbalance problems in image classification tasks. The proposed GANDA generates minority class data by exploiting majority class information to enhance the classification accuracy of minority classes. For stable GAN training, we introduce a new denoising autoencoder initialization with explicit class conditioning in the latent space, which enables the generation of definite samples. The generated samples are visually realistic and have a high resolution. Experimental results demonstrate that the proposed GANDA can considerably improve classification accuracy, especially when datasets are highly imbalanced on standard benchmark datasets (i.e., MNIST and CelebA). Our generated samples can be easily used to train conventional classifiers to enhance their classification accuracy.

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