scholarly journals Detection and Classification of Early Stage Lesions in Diabetic Retinopathy using Color Fundus Images

2019 ◽  
Vol 8 (3) ◽  
pp. 4476-4480

Detection of lesions and classification of Diabetic Retinopathy (DR) play an important role in day-to-day life. In this proposed system, colour fundus image is pre-processed using morphological operations to recover from noises and it is converted into HSV colorspace. Fuzzy C-Means Clustering algorithm (FCMC) is used for segmenting the early stage lesions such as Microaneurysms (Ma), Haemorrhages (HE) and Exudates. Hybrid features such as colour correlogram and speeded up robust features (surf) are extracted to train the classifier. Cascaded Rotation Forest (CRF) classifier is used for classification of diabetic retinopathy. The proposed system increases the accuracy of detection and it has got high sensitivity.

Deep learning (DL) as well as feature learning by unsupervised methods have made tremendous consideration in the past decades because of its great and dynamic capacity to change input data into high level depictions by means of various machine learning (ML) methods and approaches. Therefore these interests have also showed a fast and steady growth in the arena of medical image analysis, especially in Diabetic Retinopathy (DR) classification. On contradiction, manual interpretation involves excessive processing time, large amount of expertise and work. Sternness of the DR is analyzed relative to the existence of Microaneurysms (MAs), Exudates (EXs) and Hemorrhages(HEs). Spotting of DR in its early stage is crucial and important to avoid blindness. This paper proposes an algorithm to build an automated system to extract the above mentioned DR features which are the elemental and initial signs of diabetic retinopathy. Initial step in this algorithm is preprocessing of the original image. The next step in this features extraction algorithms is elimination of optic disc (OD) and blood vessels which have similar characteristic with these features. Blood vessels are segmented using Multi-Level Adaptive Thresholding. OD is segmented using morphological operations. Feature extraction and classification is achieved by using deep Bag of Feature (BoF) model which uses Speeded Up Robust Features Our method achieved 100% acuuracy in DRIVE database and over 90% accuracy for e-OPTHA database. Thus, the proposed methodology represents a track towards precise and highly automated DR diagnosis on a large substantial scale along with better sensitivity and specificity.


Diabetic Retinopathy is an eye disease which is caused by excessive sugar level in blood. Insufficient secretion of insulin hormone is the ground for evolution of diabetes. It affects most of the important organs in our body. There are two types of DR: Non Proliferative Diabetic Retinopathy and Proliferative Diabetic Retinopathy. In this proposed system techniques are introduced to detect and classify neovascularisation. Input fundus image is preprocessed by median filtering and further new vessels are segmented by using Fuzzy c-means clustering algorithm. After segmentation SIFT features are extracted and are used to train support vector machine (SVM) classifier. This automated system has been tested for 70 fundus images and accuracy of 96% is achieved


2021 ◽  
pp. 096228022098354
Author(s):  
N Satyanarayana Murthy ◽  
B Arunadevi

Diabetic retinopathy (DR) stays as an eye issue that has continuously developed in individuals who experienced diabetes. The complexities in diabetes cause harm to the vein at the back of the retina. In outrageous cases, DR could swift apparition disaster or visual impairment. This genuine impact had the option to charge through convenient treatment and early recognition. As of late, this issue has been spreading quickly, particularly in the working region, which in the end constrained the interest of an analysis of this disease from the most prompt stage. Therefore, that are castoff to protect the progressions of this disorder, revealing of the retinal blood vessels (RBVs) play a foremost role. The growth of an abnormal vessel leads to the development steps of DR, where it can be well known by extracting the RBV. The recognition of the BV for DR by developing an automatic approach is a major aim of our research study. In the proposed method, there are two major steps: one is segmentation and the second one is classification of affected retinal BV. The proposed method uses the Kinetic Gas Molecule Optimization based on centroid initialization used for the Fuzzy C-means Clustering. In the classification step, those segmented images are given as input to hybrid techniques such as a convolution neural network with bidirectional-long short-term memory (CNN with Bi-LSTM). The learning degree of Bi-LSTM is revised by using the self-attention mechanism for refining the classification accuracy. The trial consequences disclosed that the mixture algorithm achieved higher accuracy, specificity, and sensitivity than existing techniques.


2014 ◽  
Vol 22 (03) ◽  
pp. 413-428 ◽  
Author(s):  
M. PONNIBALA ◽  
S. VIJAYACHITRA

One of the greatest concerns to the personnel in the current health care sector is the severe progression of diabetes. People can often have diabetes and be completely unaware as the symptoms seem harmless when they are seen on their own. Diabetic retinopathy (DR) is an eye disease that is associated with long-standing diabetes. Retinopathy can occur with all types of diabetes and can lead to blindness if left untreated. The conventional method followed by ophthalmologists is the regular testing of the retina. As this method takes time and energy of the ophthalmologists, a new feature-based automated technique for classification and detection of exudates in color fundus image is proposed in this paper. This method reduces the work of the professionals while examining every fundus image rather than only on abnormal image. The exudates are detected from the color fundus image by applying a few pre-processing techniques that remove the optic disk and similar blood vessels using morphological operations. The pre-processed image was then applied for feature extraction and these features were utilized for classification purpose. In this paper, a novel classification technique such as self-adaptive resource allocation network (SRAN) and meta-cognitive neural network (McNN) classifier is employed for classification of images as exudates, their severity and nonexudates. SRAN classifier makes use of self-adaptive thresholds to choose the appropriate training samples and removes the redundant samples to prevent over-training. These selected samples are availed to improve the classification performance. McNN classifier employs human-like meta-cognition to regulate the sequential learning process. The meta-cognitive component controls the learning process in the cognitive component by deciding what-to-learn, when-to-learn and how-to-learn. It is therefore evident that the implementation of human meta-cognitive learning principle improves efficient learning.


2021 ◽  
Vol 13 (5) ◽  
pp. 845
Author(s):  
Yuchao Chen ◽  
Qian Huang ◽  
Jiannan Zhao ◽  
Xiangyun Hu

Lunar volcanic domes are essential windows into the local magmatic activities on the Moon. Classification of domes is a useful way to figure out the relationship between dome appearances and formation processes. Previous studies of dome classification were manually or semi-automatically carried out either qualitatively or quantitively. We applied an unsupervised machine-learning method to domes that are annularly or radially distributed around Gardner, a unique central-vent volcano located in the northern part of the Mare Tranquillitatis. High-resolution lunar imaging and spectral data were used to extract morphometric and spectral properties of domes in both the Gardner volcano and its surrounding region in the Mare Tranquillitatis. An integrated robust Fuzzy C-Means clustering algorithm was performed on 120 combinations of five morphometric (diameter, area, height, surface volume, and slope) and two elemental features (FeO and TiO2 contents) to find the optimum combination. Rheological features of domes and their dike formation parameters were calculated for dome-forming lava explanations. Results show that diameter, area, surface volume, and slope are the selected optimum features for dome clustering. 54 studied domes can be grouped into four dome clusters (DC1 to DC4). DC1 domes are relatively small, steep, and close to the Gardner volcano, with forming lavas of high viscosities and low effusion rates, representing the latest Eratosthenian dome formation stage of the Gardner volcano. Domes of DC2 to DC4 are relatively large, smooth, and widely distributed, with forming lavas of low viscosities and high effusion rates, representing magmatic activities varying from Imbrian to Eratosthenian in the northern Mare Tranquillitatis. The integrated algorithm provides a new and independent way to figure out the representative properties of lunar domes and helps us further clarify the relationship between dome clusters and local magma activities of the Moon.


Author(s):  
Saba Saleem ◽  
Javeria Amin ◽  
Muhammad Sharif ◽  
Muhammad Almas Anjum ◽  
Muhammad Iqbal ◽  
...  

AbstractWhite blood cells (WBCs) are a portion of the immune system which fights against germs. Leukemia is the most common blood cancer which may lead to death. It occurs due to the production of a large number of immature WBCs in the bone marrow that destroy healthy cells. To overcome the severity of this disease, it is necessary to diagnose the shapes of immature cells at an early stage that ultimately reduces the modality rate of the patients. Recently different types of segmentation and classification methods are presented based upon deep-learning (DL) models but still have some limitations. This research aims to propose a modified DL approach for the accurate segmentation of leukocytes and their classification. The proposed technique includes two core steps: preprocessing-based classification and segmentation. In preprocessing, synthetic images are generated using a generative adversarial network (GAN) and normalized by color transformation. The optimal deep features are extracted from each blood smear image using pretrained deep models i.e., DarkNet-53 and ShuffleNet. More informative features are selected by principal component analysis (PCA) and fused serially for classification. The morphological operations based on color thresholding with the deep semantic method are utilized for leukemia segmentation of classified cells. The classification accuracy achieved with ALL-IDB and LISC dataset is 100% and 99.70% for the classification of leukocytes i.e., blast, no blast, basophils, neutrophils, eosinophils, lymphocytes, and monocytes, respectively. Whereas semantic segmentation achieved 99.10% and 98.60% for average and global accuracy, respectively. The proposed method achieved outstanding outcomes as compared to the latest existing research works.


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