Control of the Motions of the Body’s Center of Mass and End-Points of the Lower Limbs in Patients with Mild Parkinson’s Disease During Obstacle-Crossing

2017 ◽  
Vol 38 (4) ◽  
pp. 534-543
Author(s):  
Yen-Hung Liu ◽  
Mei-Ying Kuo ◽  
Ruey-Meei Wu ◽  
Zhi-You Chen ◽  
Tung-Wu Lu
2021 ◽  
Vol 90 ◽  
pp. 211-212
Author(s):  
R. Romijnders ◽  
M. Riesen ◽  
E. Warmerdam ◽  
C. Hansen ◽  
W. Maetzler

Author(s):  
G. Belgiovine ◽  
M. Capecci ◽  
L. Ciabattoni ◽  
M. C. Fiorentino ◽  
G. Foresi ◽  
...  

2016 ◽  
Vol 8 (4) ◽  
Author(s):  
Hiroshi Kataoka ◽  
Satoshi Ueno

Parkinson’s disease (PD) is frequently associated with vasomotor symptoms such as distal cold limbs or sensitivity to cold. Coldness of the lower limbs (COL) usually occurs in winter and is often accompanied by pain, potentially causing difficulty in walking or standing. A standard dopaminergic treatment for such symptoms is yet to be established. We describe two patients with PD, who had severe COL during summer. For example, the patients wore many pairs of socks or used heating appliances in the summer. Severe COL can occur in summertime and can be intolerable or unpleasant, since it can worsen disability. The treatment with a dopamine agonist did not sufficiently decrease the severity of COL.


2020 ◽  
Vol 30 (09) ◽  
pp. 2050044
Author(s):  
Diego Castillo-Barnes ◽  
Francisco J. Martinez-Murcia ◽  
Andres Ortiz ◽  
Diego Salas-Gonzalez ◽  
Javier RamÍrez ◽  
...  

Finding new biomarkers to model Parkinson’s Disease (PD) is a challenge not only to help discerning between Healthy Control (HC) subjects and patients with potential PD but also as a way to measure quantitatively the loss of dopaminergic neurons mainly concentrated at substantia nigra. Within this context, this work presented here tries to provide a set of imaging features based on morphological characteristics extracted from I[Formula: see text]-Ioflupane SPECT scans to discern between HC and PD participants in a balanced set of [Formula: see text] scans from Parkinson’s Progression Markers Initiative (PPMI) database. These features, obtained from isosurfaces of each scan at different intensity levels, have been classified through the use of classical Machine Learning classifiers such as Support-Vector-Machines (SVM) or Naïve Bayesian and compared with the results obtained using a Multi-Layer Perceptron (MLP). The proposed system, based on a Mann–Whitney–Wilcoxon U-Test for feature selection and the SVM approach, yielded a [Formula: see text] balanced accuracy when the performance was evaluated using a [Formula: see text]-fold cross-validation. This proves the reliability of these biomarkers, especially those related to sphericity, center of mass, number of vertices, 2D-projected perimeter or the 2D-projected eccentricity, among others, but including both internal and external isosurfaces.


PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e84245 ◽  
Author(s):  
Ying-Yi Liao ◽  
Yea-Ru Yang ◽  
Yih-Ru Wu ◽  
Ray-Yau Wang

2014 ◽  
Vol 29 (7) ◽  
pp. 658-667 ◽  
Author(s):  
Ying-Yi Liao ◽  
Yea-Ru Yang ◽  
Shih-Jung Cheng ◽  
Yih-Ru Wu ◽  
Jong-Ling Fuh ◽  
...  

2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Giovanna Barros Gonçalves ◽  
Marco Antônio A. Leite ◽  
Marco Orsini ◽  
João Santos Pereira

The use of the Nintendo Wii has been considered a good alternative in the motor rehabilitation of individuals with Parkinson’s disease (PD), requiring simultaneous interaction to develop strategies for physical, visual, auditory, cognitive, psychological and social activities in the performing of virtual activities, resulting in improvement in functional performance and gait. The aim of this study was to analyze the effect of virtual sensorimotor activity on gait disorders in people with PD. Fifteen subjects with a clinical diagnosis of PD were submitted to the Unified Parkinson’s Disease Rating Scale (UPDRS III), Schwab and England Activities of Daily Living Scale (SE), Functional Independence Measure (FIM), and biomechanical gait analysis using digital images taken with a video camera before and after the treatment program. The activities with the Nintendo Wii virtual platform were standardized into three categories: aerobics, balance and Wii plus exercises. Participants carried out separate virtual exercises for 40 min, twice a week, for a total of 14 sessions. The program improved sensorimotor performance in PD gait, with an increase in stride length and gait speed, in addition to a reduction in motor impairment, especially in items of rigidity and flexibility of the lower limbs evaluated by UPDRS III, and greater functional independence, as evidenced in the SE and FIM scales. Improvements in items related to locomotion and stair climbing were also observed. The training was effective in motor recovery in chronic neurodegenerative diseases, showing improvement in motor performance and functional independence in individuals with PD.


2016 ◽  
Vol 74 (4) ◽  
pp. 287-292
Author(s):  
Lidiane Oliveira Lima ◽  
Francisco Cardoso ◽  
Luci Fuscaldi Teixeira-Salmela ◽  
Fátima Rodrigues-de-Paula

ABSTRACT Studies which have investigated muscular performance during the initial stages of Parkinson´s disease (PD) without L-dopa treatments were not found. Objective to assess whether muscular performance, work and power, of the trunk and lower limbs in L-dopa naïve patients in the early stages of PD was lower than those of healthy subjects and to compare muscular performance between the lower limbs. Method Ten subjects with PD, Hoehn and Yahr (HY) I-II, L-dopa naïve and 10 subjects in the control group were assessed with the isokinetic dynamometer. Results ANOVAs revealed that work and power measures of the trunk, hip, knee, and ankle muscular groups were lower in PD compared with the control group (p < 0.05). There were no significant differences in muscular performance between the lower limbs. Conclusion The results suggested the use of specific exercises, as rehabilitation strategies, to improve the ability to produce work and power with this population.


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