Wound Dehiscence and Role of Delayed Primary Closure in Gynaecological Oncology

2018 ◽  
Vol 16 (2) ◽  
Author(s):  
Anirudha Rohit Podder ◽  
G. S. Jyothi
Keyword(s):  
Primary Closure ◽  
Wound Dehiscence ◽  
Gynaecological Oncology ◽  
Delayed Primary Closure

scholarly journals Delayed Primary Closure of Wound Prevents Wound Infection after Surgery in Patients with Obstructive Jaundice

2020 ◽  
Vol 14 (1) ◽  
pp. 37-40
Author(s):  
Md Aslam Hossain ◽  
Md Julfiqur Rahman Khan ◽  
SM Rokonuzzaman ◽  
Md Maniruzzaman Khan ◽  
Md Mobaraque Hossain Khan ◽  
...  
Keyword(s):  
Obstructive Jaundice ◽  
Surgical Site Infection ◽  
Wound Infection ◽  
Primary Closure ◽  
Wound Dehiscence ◽  
Control Group ◽  
Site Infection ◽  
Septic Complications ◽  
Delayed Primary Closure ◽  
Experimental Group

Surgery in jaundiced patients is associated with a higher risk of postoperative complications compared with surgery in non jaundiced patients. These complications primarily consists of septic complications, hemorrhage, superficial surgical site infection (SSSI), wound dehiscence and renal disorders. Of them Surgical Site Infection (SSI) is found more commonly than other. This study was done to evaluate the effect of delayed primary closure on preventing wound infection than that of primary closure of wound after surgery in patients with obstructive jaundice. This randomized clinical trial was carried out at the Hepatobiliary and Pancreatic division of Department of Surgery in Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2012 to June 2013. A total of 88 patients were included in this study who underwent surgical intervention for obstructive jaundice. These patients were divided into two groups randomly; control group (n=44) who underwent primary closure of the wound and experimental group (n=44) who underwent delayed primary closure of the wound. Patients demography, clinical presentation, comorbidities, pre, per and post operative variables and outcome were compared between two groups. Mean age of the patients of experimental and control group was 47.91± 14.63 and 42.25±12.13 years respectively. Duration of jaundice was significantly higher in experimental group 4.91±2.87 months than in control group 3.10±1.62 months. Postoperative wound infection was found significantly higher in control group (43.2%) than that of experimental group (11.4%). Postoperative hospital stay was significantly longer in control group (18.77± 6.24 days) than in experimental group (13.52±3.61 days). Delayed primary closure of wound reduces wound infection significantly than primary closure of wound in patients with obstructive jaundice. Faridpur Med. Coll. J. Jan 2019;14(1): 37-40

scholarly journals A randomised study to evaluate wound outcome following delayed primary vs primary closure of skin in duodenal perforation peritonitis

2021 ◽  
Vol 8 (7) ◽  
pp. 2108
Author(s):  
Sajal Gupta ◽  
Vimal Bhandari ◽  
I. B. Dubey
Keyword(s):  
Primary Closure ◽  
Surgical Site Infections ◽  
Wound Dehiscence ◽  
Duodenal Perforation ◽  
P Value ◽  
Randomised Study ◽  
Delayed Primary Closure ◽  
Significant Difference ◽  
Perforation Peritonitis ◽  
Stitch Abscess

Background: This study aimed to evaluate wound outcome following delayed primary versus primary closure of skin in duodenal perforation peritonitis.Methods: The present study was a randomised interventional study that included 90 patients on accrual of duodenal perforation peritonitis which were divided into primary closure (PC) and delayed primary closure (DPC) groups comprising 45 patients each. The outcome measures were complications, surgical site infections, hospital stay and final wound status during the follow up of 30 days. Data collected was compared taking P-value <0.05 as significant.Results: The patients were in the age group of 12–60 years, with men in majority in both groups. Mean SSI score in PC and DPC was comparable (2.67 SD 1.58 vs. 2 SD1.61, P=0.058). SSI was more in PC group than DPC group (11.11% vs. 2.22%, P<0.05). Wound/pus culture was positive in 62.22% in PC and 46.67% in DPC. Major complications like wound dehiscence was noticed mainly in PC group while minor Complications like Stitch abscess, granuloma, sinus was more in DPC group. Mean of duration of stay (days) was comparable between PC and DPC group (14.07 SD 7.64 vs. 13.96 SD 6.94, P=0.805). Final wound outcome after 30 days was healthy scar in majority of patients in PC and DPC group (57.78% vs. 66.67%) with no significant difference between them (p=0.434).Conclusions: In conclusion, DPC showed comparable results with PC with similar SSI and wound healing without significant complications.

scholarly journals Delayed primary bladder’s closure in children with exstrophy, microcystis

2020 ◽  
Vol 13 (4) ◽  
pp. 146-154
Author(s):  
Yu.E. Rudin ◽  
◽  
Yu.Yu. Sokolov ◽  
A.Yu. Rudin ◽  
D.V. Marukhnenko ◽  
...  
Keyword(s):  
Primary Closure ◽  
Botulinum Toxin Type A ◽  
Bladder Exstrophy ◽  
Wound Dehiscence ◽  
Type A ◽  
Botulinum Toxin Type ◽  
Advantages And Disadvantages ◽  
Delayed Primary Closure ◽  
Bladder Neck Reconstruction ◽  
Mechanical Stretching

Introduction. The small size of the bladder plate is a poor prognostic sign for successful treatment of exstrophy. Primary closure in newborns and infants with microcystisis often accompanied by complications and relapses; there for, the approach to the treatment of this group of patients requires a more detailed analysis. The aim of the study. Identify advantages and disadvantages of delayed primary closure surgery in patients with bladder exstrophy and microcystis. Materials and methods. During the period from 1994 to 2020, 265 children with bladder exstrophy were subjected to surgery, 123 patients were newborns. There were 37 children with microcystis (bladders plate <3 cm). In 30 children, primary closure was performed at the newborn age. Seven patients with microcystis were subjected to everyday manual and mechanical stretching of the bladder and injections of botulinotoxin type A into the bladder plate (2-3 times) for 1-2 years. In 5 children the size of the bladder plate was increased from 3 cm to 6 cm, they were underwenteded delayed primary closure at the age of 1-2 years, supplemented by ureteroneoimplantation, bladder neck reconstruction, with bilateral osteotomy. Results. Complications of primary closure in patients operated on during the neonatal period (30) such as relapse of the exstrophywere observed in 10 patients (33.3%) and partial wound dehiscence in 3 children (10%). In patients with microcystis that underwent delayed primary closure after stretching the bladder, there was no relapse of exstrophy, and growth of the bladder was observed. Conclusions. In our opinion, delayed primary closure of the bladder in children with microcystis after mechanical stretching of the bladder plate in combination with injections of botulinum toxin type A into the detrusor can improve the results of correction of exstrophy.

1998 William J. Stickel Silver Award. Mechanically assisted, delayed primary closure of diabetic foot wounds

1998 ◽  
Vol 88 (10) ◽  
pp. 483-488 ◽  
Author(s):  
DG Armstrong ◽  
LA Lavery
Keyword(s):  
Diabetic Foot ◽  
Primary Closure ◽  
Wound Care ◽  
Wound Dehiscence ◽  
Healing Time ◽  
Control Group ◽  
Secondary Intention ◽  
Delayed Primary Closure ◽  
Skin Stretching ◽  
And Control

The authors evaluated the time to healing and prevalence of complications in patients undergoing mechanically assisted, delayed primary closure of diabetic foot wounds compared with a similar population who received standard wound care. A total of 55 patients were enrolled for study, with 25 in the experimental group and 30 in the control group. Patients in the experimental (stretch) group underwent mechanically assisted primary closure of their wounds using a skin-stretching device. There was no difference between the stretch and control groups with regard to any descriptive characteristics, including wound chronicity. Although the wounds were over three times as large on average in the stretch group (P &lt; .001), the stretch group reached full epithelialization approximately 40% sooner than the control group (26.4 +/- 16.0 versus 42.5 +/- 19.9 days; P &lt; .002). Eighty-eight percent of patients in the stretch group experienced wound dehiscence, at a mean time of 1.8 +/- 0.6 weeks following mechanically assisted closure. However, patients who experienced dehiscence in the stretch group healed significantly faster than patients in the control group (27.4 +/- 16.7 versus 42.5 +/- 19.9 days; P &lt; .007). The results of this study suggest that mechanically assisted closure of diabetic foot wounds may result in reduced healing time compared with healing by secondary intention.

Clinical outcome of V-Y flap with latissimus dorsi and gluteal advancement for treatment of large thoracolumbar myelomeningocele defects: a comparative study

2019 ◽  
Vol 24 (1) ◽  
pp. 75-84
Author(s):  
Mohammad Sadegh Masoudi ◽  
Mohammad Ali Hoghoughi ◽  
Fariborz Ghaffarpasand ◽  
Shekoofeh Yaghmaei ◽  
Maryam Azadegan ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Comparative Study ◽  
Surgical Site Infection ◽  
Latissimus Dorsi ◽  
Primary Closure ◽  
Wound Dehiscence ◽  
Site Infection ◽  
Gluteal Muscle ◽  
Operative Duration ◽  
Csf Leakage

OBJECTIVESurgical repair and closure of myelomeningocele (MMC) defects are important and vital, as the mortality rate is as high as 65%–70% in untreated patients. Closure of large MMC defects is challenging for pediatric neurosurgeons and plastic surgeons. The aim of the current study is to report the operative characteristics and outcome of a series of Iranian patients with large MMC defects utilizing the V-Y flap and with latissimus dorsi or gluteal muscle advancement.METHODSThis comparative study was conducted during a 4-year period from September 2013 to October 2017 in the pediatric neurosurgery department of Shiraz Namazi Hospital, Southern Iran. The authors included 24 patients with large MMC defects who underwent surgery utilizing the bilateral V-Y flap and latissimus dorsi and gluteal muscle advancement. They also retrospectively included 19 patients with similar age, sex, and defect size who underwent surgery using the primary or delayed closure techniques at their center. At least 2 years of follow-up was conducted. The frequency of leakage, necrosis, dehiscence, systemic infection (sepsis, pneumonia), need for ventriculoperitoneal shunt insertion, and mortality was compared between the 2 groups.RESULTSThe bilateral V-Y flap with muscle advancement was associated with a significantly longer operative duration (p < 0.001) than the primary closure group. Those undergoing bilateral V-Y flaps with muscle advancement had significantly lower rates of surgical site infection (p = 0.038), wound dehiscence (p = 0.013), and postoperative CSF leakage (p = 0.030) than those undergoing primary repair. The bilateral V-Y flap with muscle advancement was also associated with a lower mortality rate (p = 0.038; OR 5.09 [95% CI 1.12–23.1]) than primary closure. In patients undergoing bilateral V-Y flap and muscle advancement, a longer operative duration was significantly associated with mortality (p = 0.008). In addition, surgical site infection (p = 0.032), wound dehiscence (p = 0.011), and postoperative leakage (p = 0.011) were predictors of mortality. Neonatal sepsis (p = 0.002) and postoperative NEC (p = 0.011) were among other predictors of mortality in this group.CONCLUSIONSThe bilateral V-Y flap with latissimus dorsi or gluteal advancement is a safe and effective surgical approach for covering large MMC defects and is associated with lower rates of surgical site infection, dehiscence, CSF leakage, and mortality. Further studies are required to elucidate the long-term outcomes.

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