The Pattern of Recurrence in Carcinoma Endometrium

Background: Most endometrioid endometrial cancer are well differentiated (Grade I). Grade of the tumor is an important predictor of nodal metastasis and the discordance in histological grade of endometrial cancers between diagnostic biopsy and definitive surgery specimen was analyzed in our Institute.Methods: Around 221 patients diagnosed with carcinoma endometrium between 2006 and 2014 were taken into study. Histologic differentiation of the tumour between diagnostic biopsy and definitive surgery were analysed. All demographic data, tumor factors, follow up and recurrence were recorded.Results: Of the 221 patients taken into consideration for analysis, median age of presentation was 57 years with range between 38-77 years. The overall median body mass index was 27.70kg/m2. 66 % of patients had comorbid illness, with 33% having both diabetes and hypertension. Open staging was performed in 150 patients and laparoscopic staging in 71 patients. Mean duration of surgery was 3.06 hrs in laparoscopic staging and 2.74hrs in open staging. The median tumour size was 4cm.The median number of nodes dissected were 13. Discordance in the grade of tumour between diagnostic biopsy and surgical biopsy were 58.8% of grade 1 tumour, 16.2% of grade 2 tumours and 18.9% of grade 3 tumours.Conclusions: Discrepancies in correlation of the grade of tumour in diagnostic biopsy and tissue obtained at surgery supports the need for surgical staging in all patients.

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Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma

Annals of Surgery ◽

10.1097/sla.0000000000001149 ◽

2016 ◽

Vol 263 (3) ◽

pp. 593-600 ◽

Cited By ~ 101

Author(s):

Marcus C. B. Tan ◽

Murray F. Brennan ◽

Deborah Kuk ◽

Narasimhan P. Agaram ◽

Cristina R. Antonescu ◽

...

Keyword(s):

Risk Stratification ◽

Retroperitoneal Sarcoma ◽

Primary Retroperitoneal ◽

Pattern Of Recurrence

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Gastrointestinal Stromal Tumor: New Nodule-within-a-Mass Pattern of Recurrence after Partial Response to Imatinib Mesylate

Radiology ◽

10.1148/radiol.2353040332 ◽

2005 ◽

Vol 235 (3) ◽

pp. 892-898 ◽

Cited By ~ 102

Author(s):

Sridhar Shankar ◽

Eric vanSonnenberg ◽

Jayesh Desai ◽

Pamela J. DiPiro ◽

Annick Van Den Abbeele ◽

...

Keyword(s):

Partial Response ◽

Gastrointestinal Stromal Tumor ◽

Imatinib Mesylate ◽

Stromal Tumor ◽

Mass Pattern ◽

Pattern Of Recurrence

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Recurrent Intracerebral Hemorrhage Due to Hypertension

Neurosurgery ◽

10.1227/00006123-199004000-00005 ◽

1990 ◽

Vol 26 (4) ◽

pp. 586-590 ◽

Cited By ~ 31

Author(s):

Kyeong Seok Lee ◽

Hack Gun Bae ◽

H Gyu Yun

Keyword(s):

Intracerebral Hemorrhage ◽

Antihypertensive Therapy ◽

Cerebral Arteries ◽

Common Pattern ◽

Recurrent Hemorrhage ◽

Hypertensive Patients ◽

Intracerebral Hemorrhages ◽

The Mean ◽

Hypertensive Intracerebral Hemorrhage ◽

Pattern Of Recurrence

Abstract We report a series of 14 patients who had recurrent intracerebral hemorrhage due to hypertension. These patients comprise 2.7% of all those admitted to the Soonchunhyang University Chonan Hospital for hypertensive intracerebral hemorrhage from 1985 to 1988. Women outnumbered men by 13 to 1. The mean age of the patients was 54.5 years at the time of the first hemorrhage and 55.4 years at the time of the second hemorrhage. The mean interval between attacks was 13.1 months. All patients were hypertensive on admission, and in 10 patients hypertension had been diagnosed previously. None of the patients had received regular antihypertensive therapy, even after the first hemorrhage. Hemiplegia was the most common deficit seen after both the first and second attacks. The site of the first hemorrhage was ganglionic in 9 patients, cerebellar in 3 patients, and lobar in 2 patients. The site of the second hemorrhage was ganglionic in 9 patients and lobar in 5. The site of recurrent hemorrhage was different from the initial site in all patients except one. The most common pattern of recurrence was “ganglionic-ganglionic.” The “lobar-lobar” pattern was noted in only 1 patient. The hypertensive changes of the cerebral arteries are considered to be the major cause of these recurrent hemorrhages. We believe that recurrent intracerebral hemorrhages in hypertensive patients are not rare as previously thought. Possible reasons for the increased frequency of recurrent intracerebral hemorrhage are discussed.

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