Fluorinated TiO2-doped, glycine-functionalized MWCNTs for high-performance antibacterial agents

2019 ◽  
Vol 29 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Umadevi Mahalingam ◽  
Poornima P. Veerabaghu ◽  
Sangari Mayavan ◽  
Parimaladevi Ramasamy
Processes ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 1148 ◽  
Author(s):  
Krzesimir Ciura ◽  
Joanna Fedorowicz ◽  
Hanna Kapica ◽  
Alicja Adamkowska ◽  
Wiesław Sawicki ◽  
...  

Nowadays, fluoroquinolones (FQs) constitute one of the most important classes of antibiotics. FQs are used to treat infections caused by Gram-positive and Gram-negative species. A set of fluoroquinolone–Safirinium dye hybrids has been synthesized in our laboratory as potential new dual-action antibacterial agents. In the present study we have evaluated how such a modification influences the affinity of FQs to phospholipids. The immobilized artificial membrane (IAM) high-performance liquid chromatography (IAM-HPLC) was used as a tool for the determination of phospholipids partitioning. The obtained results indicate that the fluoroquinolone–Safirinium dye hybrids, especially the SafiriniumP conjugates, display significantly lower affinity to phospholipids than the parent FQs. Despite the fact that the hybrid structures comprise a quaternary nitrogen atom and hence are permanently charged, the attractive electrostatic interactions between the solutes and negatively charged phospholipids do not occur or occur at a lesser extent than in the case of the unmodified FQs. Since affinity of FQs to phospholipids involves molecular mechanism, which is not entirely determined by lipophilicity, assessment of phospholipid partitioning should be considered at the early stage of the development of new FQ antibiotics.


2020 ◽  
Vol 44 (4) ◽  
pp. 1508-1516 ◽  
Author(s):  
Sima Aryanejad ◽  
Ghodsieh Bagherzade ◽  
Maryam Moudi

The synthesis and characterization of novel Mn-MOF nanostructures (UoB-4) with high performance as catalysts and antibacterial agents.


2017 ◽  
Vol 9 (3) ◽  
pp. 482-489 ◽  
Author(s):  
Hua Dang ◽  
Donghong Liu ◽  
Xiangchang Hou ◽  
Yuluan Wu ◽  
Bin Wang ◽  
...  

UHPLC-MS/MS methods to determine fourteen antibacterial agents in infant disposable hygiene products were developed.


2021 ◽  
Vol 3 ◽  
Author(s):  
Hani Nasser Abdelhamid ◽  
Aji P. Mathew

Cellulose-based materials have been advanced technologies that used in water remediation. They exhibit several advantages being the most abundant biopolymer in nature, high biocompatibility, and contain several functional groups. Cellulose can be prepared in several derivatives including nanomaterials such as cellulose nanocrystals (CNCs), cellulose nanofibrils (CNFs), and TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical)-mediated oxidized cellulose nanofibrils (TOCNF). The presence of functional groups such as carboxylic and hydroxyls groups can be modified or grafted with organic moieties offering extra functional groups customizing for specific applications. These functional groups ensure the capability of cellulose biopolymers to be modified with nanoparticles such as metal-organic frameworks (MOFs), graphene oxide (GO), silver (Ag) nanoparticles, and zinc oxide (ZnO) nanoparticles. Thus, they can be applied for water remediation via removing water pollutants including heavy metal ions, organic dyes, drugs, and microbial species. Cellulose-based materials can be also used for removing microorganisms being active as membranes or antibacterial agents. They can proceed into various forms such as membranes, sheets, papers, foams, aerogels, and filters. This review summarized the applications of cellulose-based materials for water remediation via methods such as adsorption, catalysis, and antifouling. The high performance of cellulose-based materials as well as their simple processing methods ensure the high potential for water remediation.


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