The Effect of an Acute Farmers Walk Exercise Bout on Muscle Damage and Recovery in Recreationally Trained Adults

2021 ◽  
Author(s):  
Jeb F. Struder ◽  
Daniel E. Newmire ◽  
Mikaela D. Boham ◽  
Heather E. Webb
Keyword(s):  
Muscle Damage ◽  
Exercise Bout

scholarly journals Hormone therapy attenuates exercise-induced skeletal muscle damage in postmenopausal women

2009 ◽  
Vol 107 (3) ◽  
pp. 853-858 ◽  
Author(s):  
Christina M. Dieli-Conwright ◽  
Tanya M. Spektor ◽  
Judd C. Rice ◽  
E. Todd Schroeder
Keyword(s):  
Skeletal Muscle ◽  
Hormone Therapy ◽  
Mrna Expression ◽  
Postmenopausal Women ◽  
Muscle Damage ◽  
Exercise Bout ◽  
Control Group ◽  
Skeletal Muscle Damage ◽  
Tnf Α ◽  
Exercise Induced

Hormone therapy (HT) is a potential treatment to relieve symptoms of menopause and prevent the onset of disease such as osteoporosis in postmenopausal women. We evaluated changes in markers of exercise-induced skeletal muscle damage and inflammation [serum creatine kinase (CK), serum lactate dehydrogenase (LDH), and skeletal muscle mRNA expression of IL-6, IL-8, IL-15, and TNF-α] in postmenopausal women after a high-intensity resistance exercise bout. Fourteen postmenopausal women were divided into two groups: women not using HT (control; n = 6, 59 ± 4 yr, 63 ± 17 kg) and women using traditional HT (HT; n = 8, 59 ± 4 yr, 89 ± 24 kg). Both groups performed 10 sets of 10 maximal eccentric repetitions of single-leg extension on the Cybex dynamometer at 60°/s with 20-s rest periods between sets. Muscle biopsies of the vastus lateralis were obtained from the exercised leg at baseline and 4 h after the exercise bout. Gene expression was determined by RT-PCR for IL-6, IL-8, IL-15, and TNF-α. Blood draws were performed at baseline and 3 days after exercise to measure CK and LDH. Independent t-tests were performed to test group differences (control vs. HT). A probability level of P ≤ 0.05 was used to determine statistical significance. We observed significantly greater changes in mRNA expression of IL-6, IL-8, IL-15, and TNF-α ( P ≤ 0.01) in the control group compared with the HT group after the exercise bout. CK and LDH levels were significantly greater after exercise ( P ≤ 0.01) in the control group. Postmenopausal women not using HT experienced greater muscle damage after maximal eccentric exercise, indicating a possible protective effect of HT against exercise-induced skeletal muscle damage.

scholarly journals Protective role of α-actinin-3 in the response to an acute eccentric exercise bout

2010 ◽  
Vol 109 (2) ◽  
pp. 564-573 ◽  
Author(s):  
Barbara Vincent ◽  
An Windelinckx ◽  
Henri Nielens ◽  
Monique Ramaekers ◽  
Marc Van Leemputte ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Stop Codon ◽  
Premature Stop Codon ◽  
Exercise Bout ◽  
Cell Number ◽  
Protective Role ◽  
Structural Function ◽  
Marker Genes

The ACTN3 gene encodes for the α-actinin-3 protein, which has an important structural function in the Z line of the sarcomere in fast muscle fibers. A premature stop codon (R577X) polymorphism in the ACTN3 gene causes a complete loss of the protein in XX homozygotes. This study investigates a possible role for the α-actinin-3 protein in protecting the fast fiber from eccentric damage and studies repair mechanisms after a single eccentric exercise bout. Nineteen healthy young men (10 XX, 9 RR) performed 4 series of 20 maximal eccentric knee extensions with both legs. Blood (creatine kinase; CK) and muscle biopsy samples were taken to study differential expression of several anabolic (MyoD1, myogenin, MRF4, Myf5, IGF-1), catabolic (myostatin, MAFbx, and MURF-1), and contraction-induced muscle damage marker genes [cysteine- and glycine-rich protein 3 (CSRP3), CARP, HSP70, and IL-6] as well as a calcineurin signaling pathway marker (RCAN1). Baseline mRNA content of CSRP3 and MyoD1 was 49 ± 12 and 67 ± 25% higher in the XX compared with the RR group ( P = 0.01–0.045). However, satellite cell number was not different between XX and RR individuals. After eccentric exercise, XX individuals tended to have higher serum CK activity ( P = 0.10) and had higher pain scores than RR individuals. However, CSRP3 ( P = 0.058) and MyoD1 ( P = 0.08) mRNA expression tended to be higher after training in RR individuals compared with XX α-actinin-3-deficient subjects. This study suggests a protective role of α-actinin-3 protein in muscle damage after eccentric training and an improved stress-sensor signaling, although effects are small.

Short-Term β-Hydroxy-β-Methylbutyrate Supplementation Does Not Reduce Symptoms of Eccentric Muscle Damage

2001 ◽  
Vol 11 (4) ◽  
pp. 442-450 ◽  
Author(s):  
Douglas Paddon-Jones ◽  
Andrew Keech ◽  
David Jenkins
Keyword(s):  
Body Weight ◽  
Muscle Damage ◽  
Eccentric Exercise ◽  
Muscle Soreness ◽  
Exercise Bout ◽  
Similar Amount ◽  
Short Term ◽  
Placebo Condition ◽  
Post Exercise ◽  
Eccentric Muscle Damage

Purpose:We examined the effects of short-term β-hydroxy-β-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise.Methods:Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg body weight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 days prior to a bout of 24 maximal isokinetic eccentric contractions of the elbow flexors and continued throughout post-testing. Muscle soreness, upper arm girth, and torque measures were assessed pre-exercise, 15 min post-exercise, and 1,2,3, 4,7, and 10 days post-exercise.Results:No pre-test differences between HMB and CON groups were identified, and both performed a similar amount of eccentric work during the main eccentric exercise bout (p > .05). HMB supplementation had no effect on swelling, muscle soreness, or torque following the damaging eccentric exercise bout (p > .05).Conclusion:Compared to a placebo condition, short-term supplementation with 40mg/kg body weight/day of HMB had no beneficial effect on a range of symptoms associated with eccentric muscle damage. If HMB can produce an ergogenic response, a longer pre-exercise supplementation period may be necessary.

scholarly journals ProbioticBacillus coagulansGBI-30, 6086 reduces exercise-induced muscle damage and increases recovery

PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2276 ◽  
Author(s):  
Ralf Jäger ◽  
Kevin A. Shields ◽  
Ryan P. Lowery ◽  
Eduardo O. De Souza ◽  
Jeremy M. Partl ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Athletic Performance ◽  
Vertical Jump ◽  
Bacillus Coagulans ◽  
Exercise Bout ◽  
Strenuous Exercise ◽  
Post Exercise ◽  
Nitrogen Levels ◽  
And Performance ◽  
Exercise Induced

Objective.Probiotics have been reported to support healthy digestive and immune function, aid in protein absorption, and decrease inflammation. Further, a trend to increase vertical jump power has been observed following co-administration of protein and probiotics in resistance-trained subjects. However, to date the potential beneficial effect of probiotics on recovery from high intensity resistance exercise have yet to be explored. Therefore, this study examined the effect of co-administration of protein and probiotics on muscle damage, recovery and performance following a damaging exercise bout.Design.Twenty nine (n= 29) recreationally-trained males (mean ± SD; 21.5 ± 2.8 years; 89.7 ± 28.2 kg; 177.4 ± 8.0 cm) were assigned to consume either 20 g of casein (PRO) or 20 g of casein plus probiotic (1 billion CFUBacillus coagulansGBI-30, 6086, PROBC) in a crossover, diet-controlled design. After two weeks of supplementation, perceptional measures, athletic performance, and muscle damage were analyzed following a damaging exercise bout.Results.The damaging exercise bout significantly increased muscle soreness, and reduced perceived recovery; however, PROBC significantly increased recovery at 24 and 72 h, and decreased soreness at 72 h post exercise in comparison to PRO. Perceptual measures were confirmed by increases in CK (PRO: +266.8%,p= 0.0002; PROBC: +137.7%,p= 0.01), with PROBC showing a trend towards reduced muscle damage (p= 0.08). The muscle-damaging exercise resulted in significantly increased muscle swelling and Blood Urea Nitrogen levels in both conditions with no difference between groups. The strenuous exercise significantly reduced athletic performance in PRO (Wingate Peak Power; PRO: (−39.8 watts, −5.3%,p= 0.03)), whereas PROBC maintained performance (+10.1 watts, +1.7%).Conclusions.The results provide evidence that probiotic supplementation in combination with protein tended to reduce indices of muscle damage, improves recovery, and maintains physical performance subsequent to damaging exercise.

scholarly journals Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players

2019 ◽  
Vol 147 (11-12) ◽  
pp. 729-735
Author(s):  
Ivana Baralic ◽  
Tamara Stojmenovic ◽  
Marija Andjelkovic ◽  
Brizita Djordjevic ◽  
Nenad Dikic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Muscle Damage ◽  
Exercise Bout ◽  
Sport Performance ◽  
Free Oxygen Radicals ◽  
Observational Period ◽  
Specific Exercise ◽  
Basketball Players ◽  
Free Oxygen ◽  
Supplementation Period

Introduction/Objective. We determined the impact of antioxidant supplementation by GE132R on sports performance, oxidative stress markers, and muscle enzymes activities in professional female basketball players. Methods. Repetitive strength, explosive power, anaerobic endurance, and agility performance were measured before/after the 45-day supplementation period. The FORT (Free Oxygen Radicals Test) and FORD analysis (Free Oxygen Radical Defense) were assessed before/after basketball specific exercise bout, at the beginning/end of observational period. The grade of muscle damage was evaluated by aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH). Results. After supplementation period, significant difference was not recorded regarding the basic motor skills tests. Basketball specific exercise bout induced significant increase in FORT (p < 0.05) only at the beginning of supplementation period. Both FORT and FORD significantly decreased over the observational period (p < 0.001, p < 0.01, respectively). CK and LDH were remarkably lower at the end of observational period (p < 0.05), compared to the baseline. Conclusion. Exogenous supplementation with protective nutraceuticals such as those found in GE132R, could reduce acute/chronic oxidative stress and muscle damage, but had no effect on sport performance in basketball players.

CCL2 and CCR2 polymorphisms are associated with markers of exercise-induced skeletal muscle damage

2010 ◽  
Vol 108 (6) ◽  
pp. 1651-1658 ◽  
Author(s):  
Monica J. Hubal ◽  
Joseph M. Devaney ◽  
Eric P. Hoffman ◽  
Edward J. Zambraski ◽  
Heather Gordish-Dressman ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Eccentric Exercise ◽  
Exercise Bout ◽  
Large Degree ◽  
Strength Loss ◽  
Strenuous Exercise ◽  
Nucleotide Polymorphisms ◽  
Strength Recovery ◽  
Damage Response ◽  
Exercise Induced

Novel eccentric (lengthening contraction) exercise typically results in muscle damage, which manifests as prolonged muscle dysfunction, delayed onset muscle soreness, and leakage of muscle proteins into circulation. There is a large degree of variability in the damage response of individuals to eccentric exercise, with higher responders at risk for potentially fatal rhabdomyolysis. We hypothesized that single nucleotide polymorphisms (SNPs) in chemokine ligand 2 ( CCL2) and its receptor chemokine receptor 2 ( CCR2) associate with the high degrees of variability in the muscle damage response. We based this hypothesis on CCL2's roles in macrophage and satellite cell signaling in injured muscle. DNA was obtained from 157 untrained men and women following maximal eccentric exercise. Strength loss, soreness, serum creatine kinase (CK), and myoglobin levels before and during recovery from a single exercise bout were tested for association with 16 SNPs in CCL2 and CCR2. The rare alleles for rs768539 and rs3918358 (CCR2) were significantly ( P < 0.05) associated with lower preexercise strength in men, whereas CCL2 SNPs (rs13900, rs1024611, and rs1860189) and CCR2 (rs1799865) were associated with altered preexercise CK levels in women. During recovery, the rs3917878 genotype ( CCL2) was associated with attenuated strength recovery in men and an elevated CK response in women. CCR2 variants were associated with slower strength recovery in women (rs3918358) and elevated soreness (rs1799865) across all subjects. In summary, we found that SNPs in CCL2 and CCR2 are associated with exercise-induced muscle damage and that the presence of certain variants may result in an exaggerated damage response to strenuous exercise.

The effect of ionophore A23178 on the α-actinin crosslinks in the z-band of frog skeletal muscle: An EM study

1986 ◽  
Vol 44 ◽  
pp. 154-155
Author(s):  
F.T. Llados ◽  
V. Krlho ◽  
G.D. Pappas
Keyword(s):  
Muscle Damage ◽  
Transmitter Release ◽  
Skeletal Muscles ◽  
Calcium Uptake ◽  
Muscle Membrane ◽  
Frog Skeletal Muscle ◽  
Ach Release ◽  
Sustained Action ◽  
Calcium Deposits ◽  
Intense Stimulation

It Is known that Ca++ enters the muscle fiber at the junctional area during the action of the neurotransmitter, acetylcholine (ACh). Pappas and Rose demonstrated that following Intense stimulation, calcium deposits are found In the postsynaptic muscle membrane, Indicating the existence of calcium uptake In the postsynaptic area following ACh release. In addition to this calcium uptake, when mammal Ian skeletal muscles are exposed to a sustained action of the neurotransmitter, muscle damage develops. These same effects, l.e., Increased transmitter release, calcium uptake and finally muscle damage, can be obtained by Incubating the muscle with lonophore A23178.

Preventative Strategies for Exercise-Induced Muscle Damage

2004 ◽  
Vol 16 (2) ◽  
pp. 133-150 ◽  
Author(s):  
Pornratshanee Weerapong ◽  
Patria A. Hume ◽  
Gregory S. Kolt
Keyword(s):  
Muscle Damage ◽  
Exercise Induced

FOAM ROLLING AND INDICES OF AUTONOMIC RECOVERY FOLLOWING EXERCISE-INDUCED MUSCLE DAMAGE

2020 ◽  
Vol 15 (3) ◽  
pp. 429-440
Author(s):  
Anthony D’Amico ◽  
Jason Gillis ◽  
Kelley McCarthy ◽  
Jessica Leftin ◽  
Melissa Molloy ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Foam Rolling ◽  
Exercise Induced
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