Assessment of gestational age in the second trimester by real-time ultrasound measurement of the femur length

1981 ◽  
Vol 139 (5) ◽  
pp. 540-545 ◽  
Author(s):  
Gregory D. O'Brien ◽  
John T. Queenan ◽  
Stuart Campbell
Keyword(s):  
Real Time ◽  
Gestational Age ◽  
Ultrasound Measurement ◽  
Second Trimester ◽  
Femur Length

scholarly journals The accuracy of gestational age predicted from femur and humerus length in Saanen goats using ultrasonography

2012 ◽  
Vol 81 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Mohamed Abdelghafar Rihab ◽  
Hussein Ahmed Bushra ◽  
Mohamed Abdelrahim Salah ◽  
Tagelddin Ibrahim Mohamed
Keyword(s):  
Real Time ◽  
Gestational Age ◽  
Supine Position ◽  
Artificial Insemination ◽  
Multiple Regression Equation ◽  
Strong Positive Correlation ◽  
Predictive Capacity ◽  
Femur Length ◽  
Gestational Stage ◽  
Ultrasound Scanner

Serial transabdominal ultrasonographic scanning was performed to measure femur and humerus length of foetuses of Saanen goats to establish their gestational stage. Data were obtained from 38 goats that became pregnant after artificial insemination. Animals were restrained in a supine position on a special table designed for this purpose. Humerus and femur length were measured at weekly intervals starting from week 8 of gestation till the end of gestation. Real-time ultrasound scanner equipped with switchable frequency (5-7.5 MHz) micro convex probe was used in the present study. Humerus and femur length showed strong positive correlation with gestational age (r2 = 0.95). Measurements of humerus and femur of foetuses are useful indicators to predict gestational age at the 2nd and 3rd trimesters in Saanen goats. Measuring of only one bone length is quite enough. Incorporating of both measurements within a multiple regression equation did not improve predictive capacity of the bones. The results of the study were used to construct reference charts and gestational equations in Saanen goats utilizing humerus and femur measurements. In Sudan, this is the first study utilizing measurements of the femur and humerus and the first study comparing the length of the humerus and femur for predicting gestational age in Saanen goats.

scholarly journals ASSESSMENT OF GESTATIONAL AGE

2018 ◽  
Vol 21 (02) ◽  
pp. 412-417
Author(s):  
Faiza Naseem ◽  
Sabir Ali ◽  
Umbreen Basit ◽  
Naheed Fatima
Keyword(s):  
Real Time ◽  
Gestational Age ◽  
Reliable Method ◽  
Age Determination ◽  
Obstetrics And Gynecology ◽  
Third Trimester ◽  
Cross Sectional ◽  
Femur Length ◽  
Transducer Frequency ◽  
Period Of Gestation

Objective: To compare correct assessment of gestational age betweenTranscerebeller diameter versus femur length in third trimester (28-40) using first day of lastmenstrual period for actual period of gestation. Study Design: Cross-sectional descriptive study.Place and Duration of Study: Department of Obstetrics and Gynecology, Bahawal VictoriaHospital, Bahawalpur from Jun 2012 to Dec 2012. Methodology: This study was performed on327 patients in third trimester of pregnancy from 28-40 weeks fulfilling the inclusion criteria.Ultrasound measurements of transcerebellar diameter (TCD) and femur (FL) were made withcommercially available real time ultrasound equipment Toshiba Nemio-10 model 2009,Transducer frequency 50/60 Hz. Collected data was analyzed by SPSS version 10. Results: Outof 327 patients, TCD was found to give correct assessment corresponding to the gestational ageby LMP in 262 (80.1%) patients, while in 232 (70.9%) patients FL was found to give correctassessment corresponding to the gestational age by LMP. Conclusions: Transcerebellardiameter is more reliable method of gestational age determination in third trimester of pregnancythan femur length. TCD can be used as a tool to assist in the assessment of gestational age inthird trimester.

scholarly journals Assessment of gestational age in goats by Real-Time Ultrasound measuring the fetal crown rump length, and bi-parietal diameter

2018 ◽  
Vol 41 (2) ◽  
pp. 106-112
Author(s):  
Yaseen Mahmood Rasheed
Keyword(s):  
Veterinary Medicine ◽  
Real Time ◽  
Gestational Age ◽  
Second Trimester ◽  
Abdominal Ultrasonography ◽  
Crown Rump Length ◽  
Gestational Period ◽  
Relationship Of ◽  
The Relationship

     The aim of the present study was to specify the relationship of gestational period with measurement of Crown-Rump length and Bi-parietal diameter via trans-abdominal ultrasonography in goats. This study was conducted in the Faculty of Veterinary Medicine in Diyala University. The study was carried out on twelve multiparous does, their ages were between 2-5 years. Does were synchronized for estrus with PGF2α (Estrumate) at 11 days apart and naturally served to obtain pregnancy (estrus day=day 0), and subsequently Ultrasonic scanned. Weekly ultrasonographic examinations were performed using 3.5-5MHz sector transducer, from week (5-10) and (6-14) of pregnancy for measuring the Crown-Rump length and Bi-parietal diameter, respectively. The results clearly demonstrated that the relationship between gestational age and Crown-Rump length or Bi-parietal diameter were highly significant (P<0.01). The Crown-Rump length was strongly positively correlated with gestational age (R2=0.99) followed by the Bi-parietal diameter (R2=0.95). In conclusion, the gestational age of goats can be accurately estimated by trans-abdominal ultrasonography measuring of fetal Crown-Rump length and Bi-parietal diameter during first and second trimester of pregnancy.

scholarly journals Second trimester placental thickness: its’ correlation with gestational age, femur length and biparietal diameter

2018 ◽  
Vol 7 (9) ◽  
pp. 3568
Author(s):  
Sandesh Ganjoo ◽  
Shalini Devgan ◽  
Ghanshyam Dev
Keyword(s):  
Gestational Age ◽  
First Trimester ◽  
Uterine Wall ◽  
Second Trimester ◽  
Cross Sectional ◽  
Femur Length ◽  
Biparietal Diameter ◽  
Positive Linear Correlation ◽  
Minimum Age ◽  
Placental Thickness

Background: Placental thickness (PT) is the easiest placental dimension to measure, yet little is known about the normal PT. The aim of this study was to determine the normal, sonographically measured PT in millimetre (mm) in the second trimester and to determine if this measurement can be adjusted for gestational age for that time and evaluate its relationship with femur length and biparietal diameter of the fetus.Methods: The study was a cross sectional observational study, recruiting 100 consecutive, singleton pregnancies, reporting for ultrasonography (USG) between 14 weeks and 24 weeks of gestation, having undergone at least one ultrasonogram in the first trimester, with known last menstrual period (LMP). The placental thickness was measured perpendicular to the uterine wall, through the placenta at the site of cord insertion.Results: The average age of study population was 24.96 with a standard deviation (SD) of 2.70 years with the minimum age being 18 years and maximum age being 32 years. Regression analysis yielded the following mathematical relationships between PT, Gestational age (GA), Biparietal diameter (BPD) and Femur length (FL) in the second trimester. Y(PT)= 0.9366x (Gestation age)+1.655, R2 = 0.7332; Y(PT)= 0.2872x(BPD)+6.9578, R2= 0.7314; Y(PT)=0.2995x(FL)+ 10.03, R2 = 0.6186Conclusions: PT in present study showed a positive linear correlation with gestational age, FL and BPD in second trimester. Also, it can be concluded that PT may be used as a predictor of GA in women with unknown LMP.

Is there a Need for Own Median Calculation in the Second Trimester Biochemical Markers Screening?

2017 ◽  
Vol 68 (5) ◽  
pp. 1070-1072
Author(s):  
Dan Navolan ◽  
Mirela Nicolov ◽  
Simona Vladareanu ◽  
Ioana Ciohat ◽  
Marius Craina ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Biochemical Markers ◽  
Biochemical Marker ◽  
Second Trimester ◽  
Established Method ◽  
Crown Rump Length ◽  
The Difference ◽  
Fetal Aneuploidies ◽  
Singleton Pregnancies

Screening of fetal aneuploidies in early pregnancy is a well-established method in the materno-fetal medicine. The aim of our study was to analyze if the medians recommended by the manufacturers are adequate to perform an accurate screening or if there is a need for own laboratory medians calculation in second trimester biochemical marker screening.Sera were collected between 14 wp and 22 wp from 3374 singleton pregnancies. We analyzed three second trimester biochemical markers (AFP, hCG and free Estriol) concentration in all pregnant women and in a subgroup of pregnant women in which gestational age was determined based on crown-rump length. Our results showed that for all biochemical markers the difference between the manufacturer and the own calculated median was lower than 10% excepting the hCG value in the group of pregnant women in which the gestational age was determined on basis of crown-rump-length. Our results show it is recommended to replace the values of the median for hCG measurement with the own laboratory calculated medians. This does not seem to be necessary in the case of AFP and free Estriol measurement.

Second trimester contingent screening for small for gestational age neonates

2021 ◽  
Author(s):  
U. Nowacka ◽  
I. Papastefanou ◽  
A. Bouariu ◽  
A. Syngelaki ◽  
R. Akolekar ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Second Trimester

scholarly journals Evaluation of prenatal changes in fetal cardiac morphology and function in maternal diabetes mellitus using a novel fetal speckle-tracking analysis: a prospective cohort study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Dong Wang ◽  
Caixia Liu ◽  
Xinyu Liu ◽  
Ying Zhang ◽  
Yu Wang
Keyword(s):  
Diabetes Mellitus ◽  
Cohort Study ◽  
Pregnant Women ◽  
Gestational Age ◽  
Speckle Tracking ◽  
Control Group ◽  
Second Trimester ◽  
Cardiac Morphology ◽  
Sphericity Index ◽  
And Function

Abstract Background Due to metabolic changes in the second trimester and the increasing number of pregnant women with obesity and advanced maternal age, the incidence of gestational diabetes mellitus (GDM) remains high. This study aimed to evaluate the effects of GDM on fetal cardiac morphology and function, and to determine whether these changes increase with increasing estimated fetal weight (EFW). Methods Fifty-eight women with GDM (GDM group) and 58 women with a healthy pregnancy (control group) were included in this prospective observational cohort study. Each group included subgroups of 31 pregnant women with a gestational age between 24+0 weeks and 27+6 weeks as well as 27 pregnant women with a gestational age between 28+0 weeks and 40+0 weeks. For all fetuses, a cine of 2–3 s in the four-chamber view was obtained, and online speckle-tracking analysis was performed using the GE Automatic Fetal Heart Assessment Tool (fetal HQ; General Electric Healthcare Ultrasound, Zipf, Austria) to measure the global sphericity index (GSI), global longitudinal strain (GLS), fractional area change (FAC), 24-segment sphericity index (SI), and 24-segment end-diastolic diameter of the left ventricle (LV) and right ventricle (RV). Data were analyzed using the independent t-test and Wilcoxon rank-sum test, as applicable. Results The GDM group (mean HbA1c value was 5.3 ± 0.57 mmol/L) showed a lower GSI value than the control group (1.21 vs. 1.27, P = 0.000), which indicated a rounder shape of the heart. In addition, fetuses in the GDM group demonstrated significant impairment in cardiac function compared to those in the control group (LV-GLS: -18.26% vs. -22.70%, RV-GLS: -18.52% vs. -22.74%, LV-FAC: 35.30% vs. 42.36%, RV-FAC: 30.89% vs. 36.80%; P = 0.000 for all). Subgroup analyses according to gestational age (24+0–27+6 weeks and 28+0–40+0 weeks) showed that the statistical differences were retained between the GDM and control groups in each subgroup. Conclusions Fetuses of women with GDM present with signs of biventricular systolic dysfunction according to deformation analysis using fetal HQ. Additionally, the heart had a rounder shape in the GDM group than in the control group. This study showed that fetal HQ can be used to assess fetal cardiac morphology and function easily and quickly, and the effects of GDM on fetal cardiac morphology and function appeared from the second trimester. Thus, whether earlier and stricter clinical intervention was necessary remained to be further studied. Furthermore, future studies will need to supplement the effects of blood glucose levels on GLS, FAC, GSI, and 24-segment SI. Additionally, the long-term follow-up after birth should also be improved to observe the influence of changes in the indicators on the prognosis.

scholarly journals Distribution of diandric and digynic triploidy depending on gestational age

2021 ◽  
Author(s):  
Diana Massalska ◽  
Katarzyna Ozdarska ◽  
Tomasz Roszkowski ◽  
Julia Bijok ◽  
Anna Kucińska-Chahwan ◽  
...  
Keyword(s):  
Gestational Age ◽  
Pregnancy Loss ◽  
First Trimester ◽  
Parental Origin ◽  
Second Trimester ◽  
Chain Reaction ◽  
Spontaneous Pregnancy ◽  
First Trimester Of Pregnancy ◽  
Polymerase Chain ◽  
Fluorescent Polymerase Chain Reaction

Abstract Purpose To establish the distribution of diandric and digynic triploidy depending on gestational age. Methods 107 triploid samples tested prospectively in a single genetic department during a four-year period were analyzed for parental origin of triploidy by Quantitative Fluorescent Polymerase Chain Reaction (QF-PCR) (n=95) with the use of matching parental samples or by MS-MLPA (n=12), when parental samples were unavailable. Tested pregnancies were divided into three subgroups with regard to the gestational age at spontaneous pregnancy loss: <11 gestational weeks, 11–14 gestational weeks, and >14 gestational weeks. Results Diandric triploidy constituted overall 44.9% (46.5% in samples miscarried <11 gestational weeks, 64.3% in samples miscarried between 11 and 14 gestational weeks, and 27.8% in pregnancies which survived >14 gestational weeks). Conclusions The distribution of diandric and digynic triploidy depends on gestational age. The majority of diandric triploid pregnancies is lost in the first trimester of pregnancy. In the second trimester, diandric cases are at least twice less frequent than digynic ones.

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