scholarly journals Distribution of diandric and digynic triploidy depending on gestational age

2021 ◽  
Author(s):  
Diana Massalska ◽  
Katarzyna Ozdarska ◽  
Tomasz Roszkowski ◽  
Julia Bijok ◽  
Anna Kucińska-Chahwan ◽  
...  
Keyword(s):  
Gestational Age ◽  
Pregnancy Loss ◽  
First Trimester ◽  
Parental Origin ◽  
Second Trimester ◽  
Chain Reaction ◽  
Spontaneous Pregnancy ◽  
First Trimester Of Pregnancy ◽  
Polymerase Chain ◽  
Fluorescent Polymerase Chain Reaction

Abstract Purpose To establish the distribution of diandric and digynic triploidy depending on gestational age. Methods 107 triploid samples tested prospectively in a single genetic department during a four-year period were analyzed for parental origin of triploidy by Quantitative Fluorescent Polymerase Chain Reaction (QF-PCR) (n=95) with the use of matching parental samples or by MS-MLPA (n=12), when parental samples were unavailable. Tested pregnancies were divided into three subgroups with regard to the gestational age at spontaneous pregnancy loss: <11 gestational weeks, 11–14 gestational weeks, and >14 gestational weeks. Results Diandric triploidy constituted overall 44.9% (46.5% in samples miscarried <11 gestational weeks, 64.3% in samples miscarried between 11 and 14 gestational weeks, and 27.8% in pregnancies which survived >14 gestational weeks). Conclusions The distribution of diandric and digynic triploidy depends on gestational age. The majority of diandric triploid pregnancies is lost in the first trimester of pregnancy. In the second trimester, diandric cases are at least twice less frequent than digynic ones.

scholarly journals Parathyroidectomy in First Trimester of Pregnancy

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Sonia G Sharma ◽  
Steven N Levine ◽  
Rajini K Yatavelli ◽  
Manish A Shaha ◽  
Cherie Ann O Nathan
Keyword(s):  
Primary Hyperparathyroidism ◽  
Gestational Age ◽  
First Trimester ◽  
Optimal Time ◽  
Evidence Based ◽  
Second Trimester ◽  
Extreme Degree ◽  
First Trimester Of Pregnancy ◽  
Evidence Based Guidelines ◽  
Asymptomatic Disease

Abstract Primary hyperparathyroidism is not commonly diagnosed during pregnancy. For pregnant women with mild, asymptomatic disease, surgery can be avoided unless the degree of hypercalcemia becomes more severe or they develop complications. However, there are no evidence-based guidelines to assist clinicians regarding the management of primary hyperparathyroidism during pregnancy. When surgery is deemed necessary during pregnancy, the second trimester is generally considered to be the optimal time. We report the case of a 31-year-old female G1P0 who presented at 6 weeks gestation with symptoms of nausea, vomiting, polyuria, and corrected calcium of 14.8 mg/dL. Due to the extreme degree of hypercalcemia and refractory to medical treatment, it was decided that surgery could not be delayed until the second trimester. At 7w3d gestational age the patient had resection of a 37 gram, 5 × 4 × 3 cm right inferior parathyroid adenoma.

The Role of Panchakarma in recurrent pregnancy loss- A case study

2018 ◽  
Vol 6 (5th) ◽  
Author(s):  
Amol Kanodje ◽  
Vijay Kumar Nawle
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Bed Rest ◽  
First Trimester ◽  
Second Trimester ◽  
Foetal Distress ◽  
Spontaneous Pregnancy ◽  
Female Baby

Recurrent pregnancy loss is defined as three or more consecutive spontaneous losses of pregnancy. In Ayurvedic samhita “GarbhastraviVandhya” is a term for recurrent habitual abortion in the first trimester and “Garbhapata” in second trimester up to 20 weeks from the last menstrual period. Spontaneous pregnancy loss is a surprisingly common occurrence and affects 1% of couples trying to conceive. The best available data suggest that the risk of miscarriage in subsequent pregnancies is 30% after 2 losses, compared with 33% after 3 losses.1 In this case study, interpretation of cause is done on basics of Ayurvedic diagnostic parameters and management is done according to that.  Deepan, pachan, panchakarma specially Uttar vasti were planned before conception and after conception complete bed rest along with proper antenatal medicines and advices were given. There was uneventful antenatal period except foetal distress at 39.5 weeks of gestation and the patient was delivered by emergency caesarean section. A female baby with 3.1 kg birth weight was born.

scholarly journals ANTIMULLERIANHORMONE: CORRELATION WITH FIRST TRIMESTER MISCARRIAGE

2021 ◽  
Vol 9 (01) ◽  
pp. 886-891
Author(s):  
Mostafa Abdulla Elsayed ◽  
Keyword(s):  
Pregnancy Loss ◽  
Cardiac Activity ◽  
First Trimester ◽  
Assisted Conception ◽  
Statistical Software ◽  
Blood Samples ◽  
Spontaneous Pregnancy ◽  
Valuable Marker ◽  
First Trimester Of Pregnancy ◽  
Early Abortion

Objective: The present study assessed antiMullerian hormone (AMH) levels as a useful markerand a predictor of abortion in the first trimester among women younger than 35 years. Methods: Prospective study of women aged 18–34 years with a spontaneous pregnancy at less than 12 gestational weeks in Benha , Egypt, between January 2019 and November 2020 samples of blood taken at the beginning of pregnancy on booking and again at 6 weeks. Cases of anembryonic abortion and assisted conception were excluded. Blood samples were collected and assayed for serum AMH levels (on booking and at 6 weeks gestation. Data were compared between women with an embryo with no cardiac activity by ultrasound (n=50) and those with a normalpulsating embryo (n=50) by using smith statistical software. Results: Risk of pregnancy loss in the first trimester was found to be higher for low AMH (<1 ng/mL relative risk [RR], 3.66 95% confidence interval. Conclusions: LowAMH concentrations found to significantly increase the risk of abortion in the first trimester of pregnancy. Serum AMH might be a valuable marker to predict the risk of early abortion when it is below 1ng/ml.

scholarly journals The vaginal microbiota in the first trimester of pregnancy in women having history of pregnancy loss

2016 ◽  
Vol 65 (4) ◽  
pp. 44-49 ◽  
Author(s):  
Anna A. Siniakova ◽  
Elena V. Shipitsyna ◽  
Elena V. Rybina ◽  
Olga V. Budilovskaya ◽  
Tamara A. Pluzhnikova ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy Loss ◽  
Mycoplasma Hominis ◽  
First Trimester ◽  
Lactobacillus Species ◽  
Vaginal Microflora ◽  
Cultural Methods ◽  
History Of ◽  
First Trimester Of Pregnancy ◽  
Polymerase Chain

Introduction. Abnormal vaginal microflora in the first trimester of pregnancy is a risk factor for miscarriage. Opportunistic microorganisms predominate among microorganisms causing microflora disturbance. Aim. The aim of the study was to evaluate the vaginal microflora in the first trimesterфIntroduction. Abnormal vaginal microflora in the first trimester of pregnancy is a risk factor for miscarriage. Opportunistic microorganisms predominate among microorganisms causing microflora disturbance. Aim. The aim of the study was to evaluate the vaginal microflora in the first trimester of pregnancy in women having history of pregnancy loss. Matherials and Methods. Real-time polymerase chain reaction, microscopic and cultural methods were used to examine 60 pregnant women having history of pregnancy loss and 10 pregnant women with uncomplicated obstetric history. Results. Disorders of the vaginal microflora were observed only in women having history of pregnancy loss. The lactoflora in both groups was shown to consist most frequently of 3 Lactobacillus species: Lactobacillus crispatus, L. jensenii, and L. iners. However, the species L. iners were detected only in the group of women with history of pregnancy loss. Non-Lactobacillus microbiota was significantly more often observed in pregnant women having history of pregnancy loss. Facultative and obligate anaerobes were detected in both groups. The concentration of Ureaplasma spp. and Mycoplasma hominis in women in both groups had no significant differences. Conclusions. The results of this study indicate that abnormal microbiota is more often observed in women having history of pregnancy loss.of pregnancy in women having history of pregnancy loss. Matherials and Methods. Real-time polymerase chain reaction, microscopic and cultural methods were used to examine 60 pregnant women having history of pregnancy loss and 10 pregnant women with uncomplicated obstetric history. Results. Disorders of the vaginal microflora were observed only in women having history of pregnancy loss. The lactoflora in both groups was shown to consist most frequently of 3 Lactobacillus species: Lactobacillus crispatus, L. jensenii, and L. iners. However, the species L. iners were detected only in the group of women with history of pregnancy loss. Non-Lactobacillus microbiota was significantly more often observed in pregnant women having history of pregnancy loss. Facultative and obligate anaerobes were detected in both groups. The concentration of Ureaplasma spp. and Mycoplasma hominis in women in both groups had no significant differences. Conclusions. The results of this study indicate that abnormal microbiota is more often observed in women having history of pregnancy loss.

95-OR: Plasma miRNAs Levels at First Trimester of Pregnancy Predict Insulin Sensitivity Estimated at the Second Trimester of Pregnancy

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 95-OR
Author(s):  
CÉCILIA LÉGARÉ ◽  
VÉRONIQUE DESGAGNÉ ◽  
FRÉDÉRIQUE WHITE ◽  
MICHELLE S. SCOTT ◽  
PATRICE PERRON ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
First Trimester ◽  
Second Trimester ◽  
First Trimester Of Pregnancy ◽  
Plasma Mirnas

Detection of trisomy 21 by quantitative fluorescent-polymerase chain reaction in uncultured amniocytes

2003 ◽  
Vol 23 (4) ◽  
pp. 287-291 ◽  
Author(s):  
J�r�me Solassol ◽  
Ha�ssam Rahil ◽  
Vincent Sapin ◽  
Didier Lemery ◽  
Bernard Dastugue ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Trisomy 21 ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Fluorescent Polymerase Chain Reaction

scholarly journals An Infertility SRY-Negative 46, XX Male Detected by Quantitative Fluorescent Polymerase Chain Reaction

2017 ◽  
Vol 07 (08) ◽  
Author(s):  
Cao Thi Tai Nguyen ◽  
Nguyen Trung Kien ◽  
Vu Thi Nhuan ◽  
Nguyen Dac Khoa ◽  
Nguyen Chung Vieng ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Fluorescent Polymerase Chain Reaction ◽  
Xx Male

Inheritance of random amplified polymorphic DNA markers in an interspecific cross in the genus Stylosanthes

Genome ◽  
1993 ◽  
Vol 36 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Kemal Kazan ◽  
John M. Manners ◽  
Don F. Cameron
Keyword(s):  
Polymerase Chain Reaction ◽  
Dna Sequences ◽  
Rapd Markers ◽  
Dna Analysis ◽  
Random Amplified Polymorphic Dna ◽  
Interspecific Cross ◽  
Parental Origin ◽  
Chain Reaction ◽  
Stylosanthes Hamata ◽  
Polymerase Chain

The inheritance of random amplified polymorphic DNA (RAPD) markers generated via the polymerase chain reaction amplification of genomic DNA sequences in an F2 family of an interspecific cross between Stylosanthes hamata and S. scabra was investigated. An initial comparison between the parental species, S. hamata cv. Verano and S. scabra cv. Fitzroy, demonstrated that 34% of detected RAPD bands were polymorphic. Of 90 primers tested, 35 showed relatively simple and reliably scorable polymorphisms and were used for segregation analysis. Sixty F2 individuals were scored for the segregation of 73 RAPD markers and 55 of these markers fit a 3:1 ratio. Segregation of eight other RAPD markers deviated significantly from a 3:1 ratio. There was no bias in the inheritance of RAPD markers regarding parental origin of the segregating RAPD markers. Linkage analysis revealed 10 linkage groups containing a total of 44 RAPD loci. Another 10 RAPD markers (7 of maternal origin) that were polymorphic between the parents did not segregate in the F2 population. One of the maternally inherited RAPD bands hybridized to chloroplast DNA. Analysis of RAPD loci by DNA hybridization indicated that mainly repeated sequences were amplified. These data indicate that RAPDs are useful genetic markers in Stylosanthes spp. and they may be suitable for genetic mapping.Key words: genetic mapping, molecular markers, polymerase chain reaction, Stylosanthes hamata, Stylosanthes scabra.

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