Serum antibodies against oral streptococcus mutans in young children in relation to dental caries and maternal close-contacts

1985 ◽  
Vol 30 (4) ◽  
pp. 331-335 ◽  
Author(s):  
A.S. Aaltonen ◽  
J. Tenovuo ◽  
O.-P. Lehtonen ◽  
R. Saksala ◽  
O. Meurman
2015 ◽  
Vol 77 (31) ◽  
Author(s):  
Ng Yik Hean ◽  
Siti Nur Atiqah Md Othman ◽  
Norazah Basar ◽  
Khairunadwa Jemon

Dental caries is a major concern in oral healthcare. Continuous research have been performed extensively in finding new compounds that are capable to solve the problems. Phaleria macrocarpa has been identified effective against hypertension, diabetic, cancer, and diuretic acid. In this study, antiadhesion and antibiofilm activities of Streptococcus mutans were investigated using crude extracts of fruit, leaf and stem of P. macrocarpa. Minimal inhibitory concentration (MIC) assay was conducted to identify the lowest concentration of the extracts required to suppress the activity of S. mutans.  This assay confirmed that all tested extracts were able to inhibit the bacterial activities with concentration of less than 8 mg/mL and thus can be classified as a natural antimicrobial agents.  The extracts were found capable of reducing 50 to 80% of both adhesion and biofilm activity of  S. mutans at 1.56 mg/mL. Results from this study provide a preliminary data for the effectiveness of P. macrocarpa crude extracts as antiadhesion and antibiofilm agent against S. mutans and may have potential for antiseptic agent to treat oral dental caries.                     


Author(s):  
M. J. Kramer ◽  
Alan L. Coykendall

During the almost 50 years since Streptococcus mutans was first suggested as a factor in the etiology of dental caries, a multitude of studies have confirmed the cariogenic potential of this organism. Streptococci have been isolated from human and animal caries on numerous occasions and, with few exceptions, they are not typable by the Lancefield technique but are relatively homogeneous in their biochemical reactions. An analysis of the guanine-cytosine (G-C) composition of the DNA from strains K-1-R, NCTC 10449, and FA-1 by one of us (ALC) revealed significant differences and DNA-DNA reassociation experiments indicated that genetic heterogeneity existed among the three strains. The present electron microscopic study had as its objective the elucidation of any distinguishing morphological characteristics which might further characterize the respective strains.


2021 ◽  
Author(s):  
Meghana Ajay Deshpande ◽  
Sudhindra Baliga ◽  
Nilima Thosar ◽  
Nilesh Rathi ◽  
Shriramji Jyothishi ◽  
...  

PEDIATRICS ◽  
1977 ◽  
Vol 60 (5) ◽  
pp. 748-749
Author(s):  
Barbara D. Richardson ◽  
Peter E. Cleaton-Jones

The report of Shelton et al. on nursing bottle caries (Pediatrics 59:777, May 1977), which was described as a "devastating condition that may render young children dental cripples," was of great interest to us. We have recently made a study of dental caries and sucrose intake in a series of South African black and white preschool children. The condition so lucidly described by the above workers is identical to the labial caries noted in the canine and incisor teeth in our groups.1 In children under 3 years, the prevalence of labial caries in a black rural group of 109 children was 12.8%; this proportion was not significantly greater than found in 122 white urban children, namely, 9.8%.


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