Desaturation of linoleic acid in the small bowel is increased by short-term fasting and by dietary content of linoleic acid

Author(s):  
M.L. Garg ◽  
M. Keelan ◽  
A.B.R. Thomson ◽  
M.T. Clandinin
BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Song Liu ◽  
Qiongyuan Hu ◽  
Lihua Shao ◽  
Xiaofeng Lu ◽  
Xiaofei Shen ◽  
...  

Abstract Background Small bowel obstruction (SBO) is common and usually requires surgical intervention. Intestinal plication is a traditional but critical strategy for SBO in certain scenarios. This study is to compare the short-term and long-term outcome between internal and external plications in the management of SBO. Methods All patients receiving intestinal plication in our hospital were retrospectively collected. Short-term outcome including postoperative complications, reoperation, postoperative ICU stay, starting day of liquid diet and postoperative hospitalization, as well as long-term outcome including recurrence of obstruction, readmission, reoperation and death were compared between groups. Gut function at annual follow-up visits was evaluated as well. Results Nine internal and 11 external candidates were recruited into each group. The major causes of plication were adhesive obstruction, abdominal cocoon, volvulus and intussusception. Lower incidence of postoperative complication (p = 0.043) and shorter postoperative hospitalization (p = 0.049) was observed in internal group. One patient receiving external plication died from anastomosis leakage. During the 5-year follow-up period, the readmission rate was low in both groups (22.2 % vs. 9.1 %), and none of patients required reoperation or deceased. None of patients exhibited gut dysfunction, and all patients restored normal gut function after 4 years. Patients in external group demonstrated accelerated recovery of gut function after surgery. Conclusions This study compares short-term and long-term outcome of patients receiving internal or external intestinal plication. We suggest a conservative attitude toward external plication strategy. Surgical indication for intestinal plication is critical and awaits future investigations.


2017 ◽  
Vol 118 (06) ◽  
pp. 361-365
Author(s):  
P. Makovicky ◽  
E. Tumova ◽  
Z. Volek ◽  
P. Makovicky ◽  
J. M. Arnone ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
A. Pourmand ◽  
U. Dimbil ◽  
A. Drake ◽  
H. Shokoohi

Radiological imaging plays an essential role in the evaluation of a patient with suspected small bowel obstruction (SBO). In a few studies, point-of-care ultrasound (POCUS) has been utilized as a primary imaging modality in patients with suspected SBO. POCUS has been shown to be an accurate tool in the diagnosis of SBO with multiple research studies noting a consistent high sensitivity with a range of 94–100% and specificity of 81–100%. Specific sonographic findings that increase the likelihood of SBO include dilatation of small bowel loops > 25 mm, altered intestinal peristalsis, increased thickness of the bowel wall, and intraperitoneal fluid accumulation. Studies also reported that emergency physicians could apply this technique with limited and short-term ultrasound training. In this article, we aim to review the sensitivity and specificity of ultrasound examinations performed by emergency physicians in patients with suspected SBO.


2003 ◽  
Vol 42 (3) ◽  
pp. 171-179 ◽  
Author(s):  
Marco E. Turini ◽  
Julio J. Boza ◽  
Nathalie Gueissaz ◽  
Denis Moënnoz ◽  
Frank Montigon ◽  
...  

2007 ◽  
Vol 9 (8) ◽  
pp. 686-694 ◽  
Author(s):  
G. E. Reese ◽  
S. Purkayastha ◽  
H. S. Tilney ◽  
A. von Roon ◽  
T. Yamamoto ◽  
...  

2003 ◽  
Vol 81 (7) ◽  
pp. 1862-1871 ◽  
Author(s):  
K. E. Griswold ◽  
G. A. Apgar ◽  
R. A. Robinson ◽  
B. N. Jacobson ◽  
D. Johnson ◽  
...  

2002 ◽  
Vol 5 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Dorothee Fremann ◽  
Jakob Linseisen ◽  
Günther Wolfram

AbstractObjective:The habitual intake of the conjugated linoleic acid (CLA) isomer C18:2 c9t11 (rumenic acid, RA) was assessed and compared with plasma biomarkers.Design:The newly developed food-frequency questionnaire (FFQ) comprised 46 food items and was validated by means of a 7-day estimated record (7-d ER). Additionally, the dietary intake results of the FFQ, 7-d ER, the last day (1-d ER) and the last two days (2-d ER) before blood sampling of the 7-d ER were compared to the content of C18:2 c9t11 in plasma phospholipids (PL) and triglycerides (TG) as possible biomarkers.Setting:Metabolic unit of a university institute.Subjects:Fifty-seven students completed both dietary instruments. From all participants fasting blood samples were taken.Results:Mean daily intake of rumenic acid was 246 mg day−1 and 323 mg day−1 as measured by the FFQ and the 7-d-ER, respectively. The degree of correspondence between both assessment methods was acceptable; this is indicated by a total kappa value of κ = 0.31 (P < 0.01) and a Pearson correlation coefficient of r = 0.46 (P < 0.01). Rumenic acid content in plasma triglycerides was twice as high as found in phospholipids. The correlation between the intake results gained with the 7-d ER and the plasma PL contents of C18:2 c9t11 was statistically significant; this was also true for the C18:2 c9t11 values in plasma TG compared with the intake results of one or two days before blood sampling.Conclusions:Regarding RA intake, the FFQ data revealed an acceptable degree of correspondence with the 7-d ER data but failed to show significant correlations to the potential biomarkers. However, with respect to the results of the 7-d ER, the RA content in plasma PL and TG are possible biomarkers of short-term and medium-term intake, respectively.


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