Apparent unilateral visual neglect in MPTP-hemiparkinsonian monkeys is due to delayed initiation of motion

1991 ◽  
Vol 541 (1) ◽  
pp. 98-102 ◽  
Author(s):  
K.S. Bankiewicz ◽  
E.H. Oldfield ◽  
R.J. Plunkett ◽  
W.H. Schuette ◽  
D.G. Cogan ◽  
...  
2017 ◽  
Vol 10 (1) ◽  
pp. 1410975 ◽  
Author(s):  
David Mukunya ◽  
James K Tumwine ◽  
Victoria Nankabirwa ◽  
Grace Ndeezi ◽  
Isaac Odongo ◽  
...  

2021 ◽  
pp. 095148482110287
Author(s):  
Valdery Moura Junior ◽  
M Brandon Westover ◽  
Feng Li ◽  
Eyal Kimchi ◽  
Maura Kennedy ◽  
...  

Using observational data and variation in hospital admissions across days of the week, we examined the association between ED boarding time and development of delirium within 72 hours of admission among patients aged 65+ years admitted to an inpatient neurology ward. We exploited a natural experiment created by potentially exogenous variation in boarding time across days of the week because of competition for the neurology floor beds. Using proportional hazard models adjusting for socio-demographic and clinical characteristics in a propensity score, we examined the time to delirium onset among 858 patients: 2/3 were admitted for stroke, with the remaining admitted for another acute neurologic event. Among all patients, 81.2% had at least one delirium risk factor in addition to age. All eligible patients received delirium prevention protocols upon admission to the floor and received at least one delirium screening event. While the clinical and social-demographic characteristics of admitted patients were comparable across days of the week, patients with ED arrival on Sunday or Tuesday were more likely to have had delayed floor admission (waiting time greater than 13 hours) and delirium (adjusted HR = 1.54, 95%CI:1.37–1.75). Delayed initiation of delirium prevention protocol appeared to be associated with greater risk of delirium within the initial 72 hours of a hospital admission.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
F. Resch ◽  
P. Parzer ◽  
R. Oelkers-Ax ◽  
R. Brunner

In adult psychiatry early recognition and treatment of schizophrenia has become a major goal because of manifold evidence of a relation between delayed initiation of treatment and an unfavourable developmental course. The duration of untreated psychosis (DUP) seems to be significantly prolonged in adolescents compared to adults due to both a protracted sub-threshold development of psychotic features and the failure of families and health professionals to take seriously the initial signs of psychosis that mimic quasi normal adolescent emotional perturbations. Although in adults studies have shown a subset of prodromal signs and attenuated psychotic features to have predictive evidence for the development of schizophrenia, these symptoms however seem of limited specificity in adolescence. Basic symptoms represent subjective experiences of the prodromal phase and will be presented in a sample of schizophrenic adolescents in comparison to non-psychotic patients and normal controls. Results reveal that basic symptoms do not show any specificity for schizophrenia, but schizophrenics present with higher amounts of basic symptoms in the prodromal phase compared to non-psychotic controls. For early recognition a combination of psychopathological and biological markers seems fruitful. First data on perceptual closure and event related potentials of the optic system will be presented that seem to differentiate between early and late onset schizophrenia.


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