Life events and the 1-year prevalence of major depressive episode, generalized anxiety disorder, and panic disorder in a community sample

1994 ◽  
Vol 35 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Stephen C. Newman ◽  
Roger C. Bland
Keyword(s):  
Anxiety Disorder ◽  
Panic Disorder ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Community Sample ◽  
Generalized Anxiety ◽  
Major Depressive

scholarly journals Investigating differential symptom profiles in major depressive episode with and without generalized anxiety disorder: true co-morbidity or symptom similarity?

2009 ◽  
Vol 40 (7) ◽  
pp. 1113-1123 ◽  
Author(s):  
M. Sunderland ◽  
L. Mewton ◽  
T. Slade ◽  
A. J. Baillie
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
Diagnostic System ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Symptom Profile ◽  
Epidemiological Surveys ◽  
Co Morbidity

BackgroundLarge community-based epidemiological surveys have consistently identified high co-morbidity between major depressive episode (MDE) and generalized anxiety disorder (GAD). Some have suggested that this co-morbidity may be artificial and the product of the current diagnostic system. Because of the added direct and indirect costs associated with co-morbidity, it is important to investigate whether methods of diagnostic classification are artificially increasing the level of observed co-morbidity.MethodThe item response theory (IRT) log-likelihood ratio procedure was used to test for differential item functioning (DIF) of MDE symptoms between respondents with and without a diagnosis of GAD in the 2001–2002 National Epidemiological Survey on Alcohol and Related Conditions (NESARC).ResultsThe presence of GAD significantly increased the chances of reporting any symptom of MDE, with odds ratios ranging from 2.54 to 5.36. However, there was no indication of significant DIF of MDE symptoms in respondents with and without GAD.ConclusionsThe lack of any significant DIF indicates that cases with GAD do not present with a distinct MDE symptom profile, one that is consistent with the endorsement of symptoms that are conceptually similar in nature between the two disorders, compared to cases without GAD. This does not support the hypothesis that co-morbidity between MDE and GAD is artificially inflated because of the similar symptom criteria required by the current diagnostic system. Instead, MDE and GAD may be thought of as two distinct diagnostic entities that frequently co-occur because of a shared underlying trait.

scholarly journals Major Depressive Episode and Generalized Anxiety Disorder Among Sexual Minority Adults in the United States

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 860-860
Author(s):  
Cara Exten ◽  
Anna Salomaa
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Sexual Minority ◽  
Depressive Episode ◽  
Major Depressive Episode ◽  
The United States ◽  
Health Concern ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Increased Risk

Abstract Sexual minority (SM) health disparities constitute a serious public health concern, and disparities in mental health are among the most striking. Among a nationally-representative sample (NESARC-III) of US adults (aged 18-66), we used time-varying effects models (TVEM) to estimate the age-varying prevalences of past year major depressive episode (pyMDE) and generalized anxiety disorder (pyGAD) by SM status and biological sex. pyMDE and pyGAD were most common among SM women, followed by SM men, heterosexual women, and heterosexual men. pyMDE was highest among SM women and SM men in early adulthood with a second peak in the mid-50s (women)and around age 40 (men). pyGAD was highest among SM women aged 54-60 and among SM men aged 30-33. Our findings reveal that older adulthood may be a time of increased risk for pyMDE and pyGAD among SM women. Future work should explore factors that contribute to this increased risk.

scholarly journals Posttyphoon prevalence of posttraumatic stress disorder, major depressive disorder, panic disorder, and generalized anxiety disorder in a Vietnamese sample

2009 ◽  
Vol 22 (3) ◽  
pp. 180-188 ◽  
Author(s):  
Ananda B. Amstadter ◽  
Ron Acierno ◽  
Lisa K. Richardson ◽  
Dean G. Kilpatrick ◽  
Daniel F. Gros ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Major Depressive Disorder ◽  
Anxiety Disorder ◽  
Panic Disorder ◽  
Depressive Disorder ◽  
Posttraumatic Stress ◽  
Generalized Anxiety Disorder ◽  
Stress Disorder ◽  
Generalized Anxiety ◽  
Major Depressive

The impact of generalized anxiety disorder and stressful life events on risk for major depressive episodes

2006 ◽  
Vol 36 (6) ◽  
pp. 789-795 ◽  
Author(s):  
JOHN M. HETTEMA ◽  
JONATHAN W. KUHN ◽  
CAROL A. PRESCOTT ◽  
KENNETH S. KENDLER
Keyword(s):  
Anxiety Disorder ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes ◽  
The Impact

Background. Both generalized anxiety disorder (GAD) and stressful life events (SLEs) are established risk factors for major depressive disorder, but no studies exist that examine the interrelationship of their impact on depressive onsets. In this study, we sought to analyze the joint effects of prior history of GAD and recent SLEs on risk for major depressive episodes, comparing these in men and women.Method. In a population-based sample of 8068 adult twins, Cox proportional hazard models were used to predict onsets of major depression from reported prior GAD and last-year SLEs rated on long-term contextual threat.Results. For all levels of threat, prior GAD increases risk for depression, with a monotonic relationship between threat level and risk. While females without prior GAD consistently show higher depressive risk than males, this is no longer the case in subjects with prior GAD who have experienced SLEs. Rather, males appear to be more vulnerable to the depressogenic effects of both prior GAD and SLEs.Conclusion. The effects of prior GAD and SLEs jointly increase the risk of depression in both sexes, but disproportionately so in males.

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