Asymmetric: Mitoses revealed by AgNORs in developing rat blood cells

Life Sciences ◽  
1995 ◽  
Vol 56 (10) ◽  
pp. 729-734
Author(s):  
Zbyněk LikovskÝ ◽  
Karel Smetana
Keyword(s):  
1964 ◽  
Vol 19 (7) ◽  
pp. 587-592 ◽  
Author(s):  
H. Bauer ◽  
R. Wigand ◽  
W. Adam

Prototype adenoviruses and their hemagglutinins of ROSEN'S 1 group II were studied by adsorption to rat and human red blood cells and by straight and cesium chloride density gradient ultracentrifugation. Density gradient experiments showed the presence of a hemagglutinin separable from the infectious virus particles which agglutinates both rat and human cells for virus types 9, 10, 13, 19, 26, and 27. In addition, types 10, 19, and 27 have a second hemagglutinin associated with the infective particles which agglutinates rat blood cells only. Type 9 (and possibly type 8) virus has a virusbound hemagglutinin which agglutinates both kinds of blood cells. The viruses types 15, 17, 22, and 24 with hemagglutinins for rat blood cells only have two hemagglutinins, one of them associated with the virus particles. The results with type 23 were variable. Straight ultracentrifugation experiments showed a surprisingly incomplete sedimentation of the infective particles for most of the virus types studied.Differences in the resistance of various hemagglutinins to trypsin and/or heating are demonstrated.


Mutagenesis ◽  
2016 ◽  
Vol 32 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Eugenia Cordelli ◽  
Jana Keller ◽  
Patrizia Eleuteri ◽  
Paola Villani ◽  
Lan Ma-Hock ◽  
...  

1965 ◽  
Vol 20 (6) ◽  
pp. 560-563 ◽  
Author(s):  
R. Wigand ◽  
M. Stöhr

Some of the adenovirus type of Rosen’s group II exhibit weak agglutinating properties for monkey blood cells. The relation of these haemagglutinins to haemagglutinins for rat blood cells and to the infectious virus was studied by cross-absorption with blood cells and by density gradient centrifugation with caesium chloride. In the virus types studied (type 9, 13, and a wild strain of type 15) one part of the monkey cell haemagglutinin was associated with the virion and, for type 9 and 15, was inseparable from the virus-associated haemagglutinin for rat blood cells. In density gradient centrifugation a second haemagglutinin for monkey blood cells was found, separable from the virus particles and associated with the portion of higher buoyant density of the soluble haemagglutinin for rat blood cells. In type 13 and 23, haemagglutinins for monkey and rat blood cells can be separated by absorption with the heterologous blood cell species.Haemagglutinins for monkey cells are resistant to trypsin or trypsin plus subsequent heating to 55°C, in contrast to haemagglutinins for rat blood cells. Monkey cell haemagglutination is reversibly inhibited by the presence of CsCl.In haemagglutination-inhibition tests it was found that haemagglutination with monkey blood cells is more difficult to be inhibited by immune serum that haemagglutination with rat blood cells.


Author(s):  
Т.В. Чшиев

С использованием микроядерного теста было показано протекторное влияние мелаксена (10 мг/кг) при хронической экспериментальной интоксикации кадмием (0,3 мг/кг) в крови крыс, p<0,001. Исследуемый лекарственный препарат продемонстрировал способность снижать ожидаемое число микроядер и полихроматофильных эритроцитов (ПХЭ), индуцированных кадмием при двухнедельной и месячной экспозиции. При хроническом внутрижелудочном введении мелаксена не зафиксирован рост числа микроядер и ПХЭ по сравнению с контролем, p>0,05. Using the micronucleus test, the protective effect of melaxen (10 mg / kg) was shown in chronic experimental cadmium intoxication (0.3 mg / kg) in rat blood, p <0.001. The studied remedy demonstrated the ability to reduce the expected number of micronuclei and polychromatophilic red blood cells (PCE) induced by cadmium during two-week and one-month exposure. In chronic intragastric injection of melaxen, an increase in the number of micronuclei and PCEs was not registered in comparison with the control, p> 0.05.


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