Study of the intermediate states of a fissionable nucleus by the blocking technique

Author(s):  
O.V. Grusha ◽  
Yu.V. Melikov ◽  
S.Yu. Platonov ◽  
A.F. Tulinov ◽  
O.A. Yuminov
2010 ◽  
Vol 15 (3) ◽  
pp. 193-201 ◽  
Author(s):  
Elisabeth Norman

A series of vignette examples taken from psychological research on motivation, emotion, decision making, and attitudes illustrates how the influence of unconscious processes is often measured in a range of different behaviors. However, the selected studies share an apparent lack of explicit operational definition of what is meant by consciousness, and there seems to be substantial disagreement about the properties of conscious versus unconscious processing: Consciousness is sometimes equated with attention, sometimes with verbal report ability, and sometimes operationalized in terms of behavioral dissociations between different performance measures. Moreover, the examples all seem to share a dichotomous view of conscious and unconscious processes as being qualitatively different. It is suggested that cognitive research on consciousness can help resolve the apparent disagreement about how to define and measure unconscious processing, as is illustrated by a selection of operational definitions and empirical findings from modern cognitive psychology. These empirical findings also point to the existence of intermediate states of conscious awareness, not easily classifiable as either purely conscious or purely unconscious. Recent hypotheses from cognitive psychology, supplemented with models from social, developmental, and clinical psychology, are then presented all of which are compatible with the view of consciousness as a graded rather than an all-or-none phenomenon. Such a view of consciousness would open up for explorations of intermediate states of awareness in addition to more purely conscious or purely unconscious states and thereby increase our understanding of the seemingly “unconscious” aspects of mental life.


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Yoshinobu Kariya ◽  
Midori Oyama ◽  
Takato Suzuki ◽  
Yukiko Kariya

AbstractEpithelial–mesenchymal transition (EMT) plays a pivotal role for tumor progression. Recent studies have revealed the existence of distinct intermediate states in EMT (partial EMT); however, the mechanisms underlying partial EMT are not fully understood. Here, we demonstrate that αvβ3 integrin induces partial EMT, which is characterized by acquiring mesenchymal phenotypes while retaining epithelial markers. We found αvβ3 integrin to be associated with poor survival in patients with lung adenocarcinoma. Moreover, αvβ3 integrin-induced partial EMT promoted migration, invasion, tumorigenesis, stemness, and metastasis of lung cancer cells in a TGF-β-independent fashion. Additionally, TGF-β1 promoted EMT progression synergistically with αvβ3 integrin, while a TGF-β signaling inhibitor showed no effect on αvβ3 integrin-induced partial EMT. Meanwhile, the microRNA-200 family abolished the αvβ3 integrin-induced partial EMT by suppressing αvβ3 integrin cell surface expression. These findings indicate that αvβ3 integrin is a key inducer of partial EMT, and highlight a new mechanism for cancer progression.


2021 ◽  
Vol 502 (2) ◽  
pp. 1856-1863
Author(s):  
G C Mancuso ◽  
D Altamirano ◽  
M Méndez ◽  
M Lyu ◽  
J A Combi

ABSTRACT We detect millihertz quasi-periodic oscillations (mHz QPOs) using the Rossi X-ray Time Explorer (RXTE) from the atoll neutron-star (NS) low-mass X-ray binaries 4U 1608–52 and Aql X–1. From the analysis of all RXTE observations of 4U 1608–52 and Aql X–1, we find mHz QPOs with a significance level >3σ in 49 and 47 observations, respectively. The QPO frequency is constrained between ∼4.2 and 13.4 mHz. These types of mHz QPOs have been interpreted as being the result of marginally stable nuclear burning of He on the NS surface. We also report the discovery of a downward frequency drift in three observations of 4U 1608–52, making it the third source that shows this behaviour. We only find strong evidence of frequency drift in one occasion in Aql X–1, probably because the observations were too short to measure a significant drift. Finally, the mHz QPOs are mainly detected when both sources are in the soft or intermediate states; the cases that show frequency drift only occur when the sources are in intermediate states. Our results are consistent with the phenomenology observed for the NS systems 4U 1636–53 and EXO 0748–676, suggesting that all four sources can reach the conditions for marginally stable burning of He on the NS surface. These conditions depend on the source state in the same manner in all four systems.


2020 ◽  
Vol 101 (21) ◽  
Author(s):  
Xinguo Hong ◽  
Matt Newville ◽  
Yang Ding ◽  
Tetsuo Irifune ◽  
Genda Gu ◽  
...  

Biopolymers ◽  
1994 ◽  
Vol 34 (2) ◽  
pp. 261-272 ◽  
Author(s):  
Donald T. Haynie ◽  
Ernesto Freire
Keyword(s):  

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Laura Orellana ◽  
Ozge Yoluk ◽  
Oliver Carrillo ◽  
Modesto Orozco ◽  
Erik Lindahl

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