Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse

1988 ◽  
Vol 41 (1) ◽  
pp. 99-103 ◽  
Author(s):  
K.L. Dooley ◽  
J.F.C. Stavenuiter ◽  
J.G. Westra ◽  
F.F. Kadlubar
Keyword(s):  
Pyrolysis Product ◽  
Human Carcinogen ◽  
B6c3f1 Mouse

scholarly journals Degradation of trinitrotoluene by transgenic nitroreductase in Arabidopsis plants

2018 ◽  
Vol 64 (No. 8) ◽  
pp. 379-385 ◽  
Author(s):  
Zhu Bo ◽  
Han Hongjuan ◽  
Fu Xiaoyan ◽  
Li Zhenjun ◽  
Gao Jianjie ◽  
...  
Keyword(s):  
Transgenic Plants ◽  
Transgenic Arabidopsis ◽  
Environmental Pollutant ◽  
Specific Rate ◽  
Wild Type Plant ◽  
Wild Type ◽  
Fresh Weight ◽  
Human Carcinogen ◽  
Specific Rate Constant ◽  
Nitroreductase Activity

The explosive 2,4,6-trinitrotoluene (TNT) is a highly toxic and persistent environmental pollutant. TNT is toxic to many organisms, it is known to be a potential human carcinogen, and is persistent in the environment. This study presents a system of phytoremediation by Arabidopsis plants developed on the basis of overexpression of NAD(P)H-flavin nitroreductase (NFSB) from the Sulfurimonas denitrificans DSM1251. The resulting transgenic Arabidopsis plants demonstrated significantly enhanced TNT tolerance and a strikingly higher capacity to remove TNT from their media. The highest specific rate constant of TNT disappearance rate was 1.219 and 2.297 mL/g fresh weight/h for wild type and transgenic plants, respectively. Meanwhile, the nitroreductase activity in transgenic plant was higher than wild type plant. All this indicates that transgenic plants show significantly enhanced tolerances to TNT; transgenic plants also exhibit strikingly higher capabilities of removing TNT from their media and high efficiencies of transformation.

Oral N-acetylcysteine protects against perfluoroisobutene toxicity in rats

1997 ◽  
Vol 16 (4) ◽  
pp. 212-216 ◽  
Author(s):  
Alison F Lailey
Keyword(s):  
Oral Administration ◽  
Pulmonary Oedema ◽  
Plasma Levels ◽  
Pyrolysis Product ◽  
Lavage Fluid ◽  
Lethal Effects ◽  
Duration Of Protection ◽  
Gas Exposure

1 Perfluoroisobutene, a pyrolysis product of polytetra fluoroethene may cause pulmonary oedema and death when inhaled. Oral N-acetylcysteine has shown protection against inhalation of perfluoroisobutene and in this study we have tried to elucidate the mechanism by which protection is mediated. 2 Protection against the lethal effects of inhaled per fluoroisobutene has been shown when N-acetylcys teine has been orally administered 4, 6 or 8 h before gas exposure. 3 Plasma levels of cysteine, glutathione and N-acetylcys teine were increased for up to 7 h following oral administration of Nac. 4 N-acetylcysteine was not detected in the bronchio alveolar lavage fluid following oral administration. 5 Duration of protection in vivo has been related to the duration of increased thiol levels in the plasma.

Suitability of rice straw for biochar production through slow pyrolysis: Product characterization and thermodynamic analysis

2021 ◽  
pp. 100818
Author(s):  
Anil Kumar Sakhiya ◽  
Abhijeet Anand ◽  
Imlisongla Aier ◽  
Virendra Kumar Vijay ◽  
Priyanka Kaushal
Keyword(s):  
Rice Straw ◽  
Thermodynamic Analysis ◽  
Pyrolysis Product ◽  
Slow Pyrolysis ◽  
Product Characterization

IS TRICHLOROETHYLENE A HUMAN CARCINOGEN

Epidemiology ◽  
1998 ◽  
Vol 9 (Supplement) ◽  
pp. S100
Author(s):  
D Wartenberg ◽  
D Reyner ◽  
C S Scott
Keyword(s):  
Human Carcinogen
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