Sample size requirements for prospective studies, with examples for coronary heart disease

1989 ◽  
Vol 42 (7) ◽  
pp. 639-648 ◽  
Author(s):  
A PHILLIPS
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Sample Size ◽  
Prospective Studies

Is Diabetes Mellitus a Coronary Heart Disease Equivalent? Results of a Meta-Analysis of Prospective Studies

2007 ◽  
Vol 60 (11) ◽  
pp. 1167-1176
Author(s):  
José Miguel González-Clemente ◽  
Silvia Palma ◽  
Jaume Arroyo ◽  
Carme Vilardell ◽  
Assumpta Caixàs ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Prospective Studies ◽  
Meta Analysis

scholarly journals The impact of clinical and population strategies on coronary heart disease mortality: an assessment of Rose’s big idea

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mohadeseh Ahmadi ◽  
Bruce Lanphear
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Coronary Heart Disease Mortality ◽  
Cross Sectional ◽  
Population Strategy ◽  
Chd Risk Factors ◽  
The Impact ◽  
Clinical Strategy

Abstract Background Coronary heart disease (CHD), the leading cause of death worldwide, has declined in many affluent countries but it continues to rise in industrializing countries. Objective To quantify the relative contribution of the clinical and population strategies to the decline in CHD mortality in affluent countries. Design Meta-analysis of cross-sectional and prospective studies. Data sources PubMed and Web of Science from January 1, 1970 to December 31, 2019. Method We combined and analyzed data from 22 cross-sectional and prospective studies, representing 500 million people, to quantify the relative decline in CHD mortality attributable to the clinical strategy and population strategy. Result The population strategy accounted for 48% (range = 19 to 73%) of the decline in CHD deaths and the clinical strategy accounted for 42% (range = 25 to 56%), with moderate inconsistency of results across studies. Conclusion Since 1970, a larger fraction of the decline in CHD deaths in industrialized countries was attributable to reduction in CHD risk factors than medical care. Population strategies, which are more cost-effective than clinical strategies, are under-utilized.

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