ASYMPTOMATIC AUTOIMMUNE THYROIDITIS AND CORONARY HEART-DISEASE Cross-sectional and Prospective Studies

The Lancet ◽  
1977 ◽  
Vol 310 (8030) ◽  
pp. 155-158 ◽  
Author(s):  
P BASTENIE
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mohadeseh Ahmadi ◽  
Bruce Lanphear

Abstract Background Coronary heart disease (CHD), the leading cause of death worldwide, has declined in many affluent countries but it continues to rise in industrializing countries. Objective To quantify the relative contribution of the clinical and population strategies to the decline in CHD mortality in affluent countries. Design Meta-analysis of cross-sectional and prospective studies. Data sources PubMed and Web of Science from January 1, 1970 to December 31, 2019. Method We combined and analyzed data from 22 cross-sectional and prospective studies, representing 500 million people, to quantify the relative decline in CHD mortality attributable to the clinical strategy and population strategy. Result The population strategy accounted for 48% (range = 19 to 73%) of the decline in CHD deaths and the clinical strategy accounted for 42% (range = 25 to 56%), with moderate inconsistency of results across studies. Conclusion Since 1970, a larger fraction of the decline in CHD deaths in industrialized countries was attributable to reduction in CHD risk factors than medical care. Population strategies, which are more cost-effective than clinical strategies, are under-utilized.


2018 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Laila Kamila ◽  
Maulidiyah Salim

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang  menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian  ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari  α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.


BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048590
Author(s):  
Kewei Wang ◽  
Yuanqi Wang ◽  
Ruxing Zhao ◽  
Lei Gong ◽  
Lingshu Wang ◽  
...  

ObjectiveThe objective of this study was to evaluate the influence of secondhand smoke (SHS) exposure during childhood on type 2 diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease among Chinese non-smoking women.MethodsIn this cross-sectional study, the SHS exposure data in childhood were obtained using a questionnaire survey. Self-reported childhood SHS exposure was defined as the presence of at least one parent who smoked during childhood.ResultsOf the 6522 eligible participants, 2120 Chinese women who had never smoked were assessed. The prevalence of SHS exposure in the entire population was 28.1% (596). SHS exposure during childhood was not significant for the standard risk factors of type 2 diabetes mellitus (p=0.628) and hypertension (p=0.691). However, SHS was positively associated with hyperlipidaemia (p=0.037) after adjusting for age, obesity, education status, physical activity, alcohol consumption, current SHS exposure status, diabetes mellitus and hypertension. In addition, childhood SHS increased the occurrence of coronary heart disease (p=0.045) among non-smokers after further adjusting for hyperlipidaemia.ConclusionSHS exposure during childhood is associated with prevalent hyperlipidaemia and coronary heart disease in adulthood among non-smoking Chinese women.


2005 ◽  
Vol 93 (05) ◽  
pp. 955-963 ◽  
Author(s):  
George Smith ◽  
Ann Rumley ◽  
Gordon Lowe ◽  
Shah Ebrahim ◽  
Debbie Lawlor

SummaryA cross sectional and prospective analysis of 3,745 British women aged 60–79 years at baseline was undertaken. Among these women there were 570 prevalent cases of coronary heart disease (CHD) and 151 new cases among 12,641 person-years of follow up of women who were free of CHD at baseline. Both fibrinogen and CRP were associated with indicators of socioeconomic position in childhood and adulthood and there was a cumulative effect of socioeconomic position from across the life course. The age-adjusted odds ratio (95% confidence interval) of prevalent CHD for a 1 unit (1 g/L) increase in fibrinogen was 1.29 (1.12, 1.49); with full adjustment for all potential confounding factors this attenuated to 1.09 (0.93, 1.28). The hazards ratio for incident CHD among those free of disease at baseline was 1.28 (1.00, 1.64); with full adjustment for all potential confounding factors this attenuated to 1.09 (0.84, 1.44). Similar effects of adjustment for confounding factors were seen for the associations between CRP and both prevalent and incident CHD. By contrast, the strong positive association between smoking (an established causal risk factor for CHD) and CHD was not attenuated by adjustment for life course socioeconomic position or other risk factors. We conclude that fibrinogen and CRP predict CHD but may not be causally related to it.


2021 ◽  
Vol 3 (2) ◽  
pp. 181-191
Author(s):  
Rika Yulendasari ◽  
Usastiawaty Cik Ayu Saadiah Isnainy ◽  
Rima Ary Pradisca

ABSTRACT: RELATIONSHIP BETWEEN PHYSICAL ACTIVITY AND FAMILY HISTORY WITH CORONARY HEART DISEASE AT PUSKESMAS  BANJARSARI METRO Introduction: Based on data in coronary heart events Metro City 2018 total which is 1,309 new cases. For new diseases 190 men and 22 for women cases,  for old cases 369 men and 528 women in 2019 have a very drastic decrease, with total of new and old 229 patients with heart disease , for new diseases which is 32 men and 57 cases and women, for an old cases which is 60 cases for men and 80 cases for women.Purpose:  to known relations between physical activity and family history with coronary heart disease at Puskesmas Banjarsari Metro in 2020.Method: quantitative research type, analytical survey research plan with cross sectional approach, population and sample in research patients with heart failure are22 respondents. Univariate and bivariate data analysis used chi square test.Result : From 23 respondents, 13 respondents (56,5%) with low activity, families at risk which is 14 respondents (55,0%),  12 respondent (52,2%) with coronary heart, results of statistical tests using the chi square test obtained p-value = 0,022(< 0.05) , p-value = 0,006(< 0.05).Conclusion : Results of using the chi square test obtained p-value = 0,022(< 0.05) that means there is a relations between physical actiivity with occurrence coronary heart disease in Puskesmas Banjarsari Kota Metro 2020. Results of using the chi square test obtained p-value = 0,006(< 0.05) that means there is a relations between history of family with occurrence coronary heart disease in Puskesmas Banjarsari Kota Metro 2020. For peoples who risk of coronary heart disease (CHD) to behave healthy living by maintaining a diet by consuming foods that conform to diet coronary heart patients, avoid smoking, not consuming alcohol beverages, maintain weight stability and exercise regulary. Keywords : Knowledge, Self Care, Quality of life.       INTISARI:HUBUNGAN ANTARA AKTIVITAS FISIK DAN RIWAYAT KELUARGA DENGAN KEJADIAN PENYAKIT JANTUNG KORONER DI PUSKESMAS RAWAT INAP BANJARSARI KOTA METRO  Pendahuluan: Berdasarkan data kejadian jantung koroner di Kota Metro tahun 2018 pada berdasarkan jumlah kasus baru dan lama  sebanyak 1.309 dengan pembagian penyakit baru, laki-laki sebanyak 190 orang, perempuan sebanyak 22 orang, dan kasus lama, laki-laki sebanyak 369 orang, perempuan sebanyak 528 orang, pada tahun 2019 mengalami penurunan yang sangat drastis, yaitu total pasien jantung baru dan lama sebanyak 229 orang, dengan pembagian penyakit baru, laki-laki sebanyak 32 orang, perempuan sebanyak 57 orang, dan kasus lama, laki-laki sebanyak 60 orang, perempuan sebanyak 80 orang.Tujuan: Diketahui hubungan antara aktivitas fisik dan riwayat keluarga dengan kejadian penyakit jantung koroner di Puskesmas Banjarsari Kota Metro Tahun 2020.Metode: Jenis penelitian kuantitatif, rancangan penelitian survey analitik dengan pendekatan cross sectional, populasi dan sampel dalam penelitian ini adalah pasien gagal jantung sebanyak 22  responden, Analisa data menggunakan univariat dan bivariat menggunakan uji chi square.Hasil : Dari 23 responden dengan aktivitas kurang sebanyak 13 responden (56,5%), riwayat keluarga beresiko sebanyak 14 responden (55,0%),  jantung koroner sebanyak 12 responden (52,2%), Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0,022 (< 0.05) , p-value = 0,006 (< 0.05).Kesimpulan : Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0,022 (< 0.05) yang artinya terdapat hubungan antara aktivitas fisik dengan kejadian penyakit jantung koroner di Puskesmas Banjarsari Kota Metro Tahun 2020. Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0,006 (< 0.05) yang artinya terdapat hubungan antara riwayat keluarga dengan kejadian penyakit jantung koroner di Puskesmas Banjarsari Kota Metro  Tahun 2020Bagi seseorang yang mempunyai resiko terhadap terjadinya Penyakit Jantung Koroner (PJK) untuk berperilaku hidup sehat dengan jalan menjaga pola makan dengan jalan mengkonsumsi makanan yang sesuai dengan pola diit penderita PJK, menghindari merokok, tidak mengkonsumsi minuman beralkohol, menjaga kestabilan berat badan dan berolah raga secara teratur. Kata Kunci      : Pengetahuan, Self Care, Kualitas Hidup 


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