PS-30-1 Discrimination among schizophrenic, depressive and normal control groups using exploratory eye movement, P300 and reaction time

Author(s):  
Sakae Takahashi ◽  
Eiichi Tanabe ◽  
Mei-Ian Xia ◽  
Teiichiro Sakai ◽  
Eisuke Matsushima ◽  
...  
Data in Brief ◽  
2020 ◽  
Vol 29 ◽  
pp. 105108
Author(s):  
Felix-Sebastian Koch ◽  
Anett Sundqvist ◽  
Ulrika Birberg Thornberg ◽  
Michael T. Ullman ◽  
Rachel Barr ◽  
...  

2018 ◽  
Vol 315 (1) ◽  
pp. E99-E109 ◽  
Author(s):  
Sunmin Park ◽  
Da Sol Kim ◽  
Eun Seon Kang ◽  
Da Bin Kim ◽  
Suna Kang

We evaluated the effects of intracerebroventricular administration (ICV) of brain estrogen and progesterone on menopausal symptoms and their effects on the secretion of follicle-stimulating hormone(FSH) and luteinizing hormone (LH) in estrogen-deficient rats. Three weeks after ovariectomy (OVX) or sham operation, OVX rats were given ICV infusions of either 17β-estradiol (4 μg/day; ICV-E), progesterone(0.8 μg/day; ICV-P), or vehicle (control) for 4 wk. OVX rats in the positive-control group were orally provided 150 μg 17β-estradiol·kg body wt−1·day−1. Sham rats had ICV vehicle infusion (normal-control). Serum 17β-estradiol levels of ICV-E and ICV-P groups were higher than the control group but much lower than the normal- and positive-control groups. Tail skin temperature was higher in the control group than the other groups. Serum FSH and LH levels were much higher in the control group than positive- and normal-control groups, but ICV-E and ICV-P lowered the levels similar to the normal-control treatment. ICV-E and ICV-P prevented the decreased energy expenditure in OVX rats. Homeostasis model assessment estimate of insulin resistance was lowered in the descending order of the control, positive-control, ICV-P, ICV-E, and normal-control treatments. The decreased bone mineral density was prevented by the positive-control, ICV-E, and ICV-P treatments. The control group exhibited decreased short-term memory and spatial memory compared with the other groups. Surprisingly, the control group exhibited a decreased richness of the gut microbiome compared with normal-control group, and ICV-E protected against the decrease the most. In conclusion, small amounts of brain estrogen and, to some extent, progesterone improved menopausal symptoms by decreasing serum FSH levels and maintaining the diversity of the gut microbiome in estrogen-deficient rats.


Author(s):  
Nasrin Jaberghaderi ◽  
Mansour Rezaei ◽  
Mitra Kolivand ◽  
Azita Shokoohi

Objective: This study was conducted to examine and compare the effectiveness of cognitive behavioral therapy (CBT) and eye movement desensitization and reprocessing (EMDR) in child victims of domestic violence (child physical abuse and/or witnessing parents’ conflicts). Method: A total of 139 girls and boys, aged 8-12 years, were randomly assigned into CBT (n = 40), EMDR (n = 40), or control groups (n=59). All children received up to 12 individual treatment sessions over 4–12 weeks. Blind assessment was done before and 2 weeks after the treatment and on a variety of teacher-parent-rated and self-report measures of posttraumatic symptomatology, depression, anxiety, and behavior problems. Results: CBT and EMDR were effective in ameliorating psychological sequelae of victims of domestic violence on the measured variables (p =.001). Comparison of the treatment and control groups suggested moderate to high practical significance in treatment groups vs controls. Conclusion: Both CBT and EMDR can help children to greatly recover from the outcomes of domestic violence in comparison with control group. Moreover, structured trauma treatments are strongly recommended and can be used for children


2021 ◽  
Vol 12 ◽  
Author(s):  
Wen He ◽  
Yazheng Ji ◽  
Xiating Wei ◽  
Fan Wang ◽  
Feng Xu ◽  
...  

Objective: To investigate the efficacy of eye movement technique for the treatment of executive dysfunction of patients with stroke.Methods: This was a prospective, single-blinded, randomized, controlled, single-center clinical trial conducted from June 2018 to December 2019 in patients with stroke. The patients were randomized 1:1 to the routine (conventional management) and eye-move group (routine management plus eye movement technique: 5-min goal management training, 5-min computer-aided working memory, and 10 min of inhibitory control training and set conversion training). The intervention lasted 6 weeks, followed by a 4-week follow-up. The primary endpoint was the Behavioral Assessment of the Dysexecutive Syndrome (BADS) score. The secondary endpoints mainly included the Montreal Cognitive Assessment (MoCA), Wisconsin Card Sorting Test (WCST), and modified Barthel Index (MBI) scores.Results: Sixty-four patients were enrolled (32/group). After the 6-week intervention, the BADS and WCST scores of the eye-move group were significantly improved than those of the routine group (all P < 0.05), but the effects were attenuated in certain subscores after follow-up (all P > 0.05). The MoCA and MBI scores of the eye-move group were significantly higher, and the reaction time was significantly lower than those of the routine group at 4 weeks after the intervention (all P < 0.05). After follow-up, the MBI scores of the eye-move group were still higher than that of the routine group (P < 0.001), but there were no differences for MoCA scores and reaction time (both P > 0.05).Conclusion: The eye movement technique could improve the executive function of patients with stroke. These results have to be confirmed.This was a prospective, single-blinded, randomized, controlled, single-center clinical trial (ChiCTR2000036393).Clinical Trial Registration: [www.chictr.org.cn], identifier [ChiCTR2000036393].


2019 ◽  
Vol 8 (4) ◽  
pp. 13 ◽  
Author(s):  
Deepmala Mazumdar ◽  
Najiya S. Kadavath Meethal ◽  
Manish Panday ◽  
Rashima Asokan ◽  
Gijs Thepass ◽  
...  

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