U.S. computing leaders, including the National Science Foundation, have
partnered with universities, government agencies, and the private sector
to accelerate research into responses to COVID-19 – providing an
unprecedented collection of resources that include some of the fastest
computers in the world. This current work expands on last month’s
Leadership Computing article by continuing to showcase the range of
contributions that the national cyberinfrastructure is making to global
efforts to stop the pandemic. This article touches on research efforts
to learn how SARS-CoV-2 spreads among different populations, the biology
and structure of the virus and its mechanisms of infection, and to
develop effective vaccines for prevention and antiviral therapies for
treatment. Even though we are still early in the process of developing
an effective therapeutic response, the rapid mobilization of the
national research cyberinfrastructure is a timely reminder of the
strategic importance of robust, ongoing investments in large-scale
scientific computing.