Immune Response—The Impact of Biological Sex and Gender

2017 ◽  
pp. 309-321
Author(s):  
Sabine Oertelt-Prigione
Keyword(s):  
Immune Response ◽  
Sex And Gender ◽  
Biological Sex ◽  
And Gender ◽  
The Impact

scholarly journals Gender Differences in Diabetic Kidney Disease: Focus on Hormonal, Genetic and Clinical Factors

2021 ◽  
Vol 22 (11) ◽  
pp. 5808
Author(s):  
Annalisa Giandalia ◽  
Alfio Edoardo Giuffrida ◽  
Guido Gembillo ◽  
Domenico Cucinotta ◽  
Giovanni Squadrito ◽  
...  
Keyword(s):  
Gender Differences ◽  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Clinical Manifestations ◽  
Current Evidence ◽  
Sex And Gender ◽  
Clinical Factors ◽  
Diabetic Kidney ◽  
And Gender ◽  
The Impact

Diabetic kidney disease (DKD) is one of the most serious complications of both type 1 (T1DM) and type 2 diabetes mellitus (T2DM). Current guidelines recommend a personalized approach in order to reduce the burden of DM and its complications. Recognizing sex and gender- differences in medicine is considered one of the first steps toward personalized medicine, but the gender issue in DM has been scarcely explored so far. Gender differences have been reported in the incidence and the prevalence of DKD, in its phenotypes and clinical manifestations, as well as in several risk factors, with a different impact in the two genders. Hormonal factors, especially estrogen loss, play a significant role in explaining these differences. Additionally, the impact of sex chromosomes as well as the influence of gene–sex interactions with several susceptibility genes for DKD have been investigated. In spite of the increasing evidence that sex and gender should be included in the evaluation of DKD, several open issues remain uncovered, including the potentially different effects of newly recommended drugs, such as SGLT2i and GLP1Ras. This narrative review explored current evidence on sex/gender differences in DKD, taking into account hormonal, genetic and clinical factors.

The impact of stereotyped perceptions of entrepreneurship and gender-role orientation on Slovak women’s entrepreneurial intentions

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Magdalena Adamus ◽  
Vladimíra Čavojová ◽  
Jakub Šrol
Keyword(s):  
Gender Role ◽  
Entrepreneurial Intentions ◽  
Role Orientation ◽  
Gender Role Orientation ◽  
Content Type ◽  
Biological Sex ◽  
Working Age ◽  
Successful Entrepreneurs ◽  
And Gender ◽  
The Impact

Purpose This study aims to investigate how congruence between the image of a successful entrepreneur and one’s own gender-role orientation affects entrepreneurial intentions (EI). Design/methodology/approach A total of 552 working-age adults (49.5% women) answered questions on gender-role orientation, perception of a successful entrepreneur, EI, antecedents of EI (perceived behavioural control (PBC), subjective norm (SN), attitude towards entrepreneurship), entrepreneurial self-efficacy and risk aversion. Findings Women reported a lower EI than men, and both male and female participants perceived successful entrepreneurs as masculine. In the final model, biological sex did not predict EIs. Rather, it was associated with the extent to which participants felt they resembled successful entrepreneurs, which, in turn, predicted greater levels of PBC, SNs and attitudes towards entrepreneurship, as well as greater EI. Originality/value The study is one of the first to study joint impacts of biological sex, gender and congruence on EIs.

scholarly journals Breaking the Binary

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Lucy Mercer-Mapstone ◽  
Sarah Bajan ◽  
Kasia Banas ◽  
Arthur Morphett ◽  
Kristine McGrath
Keyword(s):  
Minority Group ◽  
First Year ◽  
Sex And Gender ◽  
Biological Sex ◽  
Positive Attitudes ◽  
Student Cohorts ◽  
The Difference ◽  
Students Attitudes ◽  
And Gender ◽  
Partnership Approach

The need to make higher education curricula gender-inclusive is increasingly pressing as student cohorts diversify. We adopted a student-staff partnership approach to design, integrate, and evaluate a module that taught first-year science students the difference between biological sex, gender identity, gender expression, and sexual orientation in the context of genetics concepts at an Australian university. This module aimed to break the binary in misconceptions of both sex and gender, emphasising that both exist on separate spectra. Data triangulation was used to evaluate students’ attitudes towards the module and their learning of module concepts. Students’ attitudes were positive overall, and evaluation of students’ learning indicated that the majority of students understood and retained key concepts, while also identifying common misconceptions. Perhaps the most important finding was that students who identified as belonging to a minority group had significantly more positive attitudes towards the module than non-minority students. This finding supports previous research that has found inclusive curricula have greater benefit for students from minority backgrounds, indicating the importance of making such curriculum enhancements. Our results speak to both the co-creation process and students’ learning outcomes, providing valuable insights for practitioners both within science and beyond.

scholarly journals The Impact of Sex and Gender on Adaptation to Space: Executive Summary

2014 ◽  
Vol 23 (11) ◽  
pp. 941-947 ◽  
Author(s):  
Saralyn Mark ◽  
Graham B.I. Scott ◽  
Dorit B. Donoviel ◽  
Lauren B. Leveton ◽  
Erin Mahoney ◽  
...  
Keyword(s):  
Sex And Gender ◽  
Executive Summary ◽  
And Gender ◽  
The Impact

scholarly journals The Impact of Sex and Gender on the Multidisciplinary Management of Care for Persons With Parkinson's Disease

2020 ◽  
Vol 11 ◽  
Author(s):  
Irene Göttgens ◽  
Angelika D. van Halteren ◽  
Nienke M. de Vries ◽  
Marjan J. Meinders ◽  
Yoav Ben-Shlomo ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Multidisciplinary Management ◽  
Sex And Gender ◽  
And Gender ◽  
Management Of Care ◽  
The Impact

scholarly journals Three Decades of Progress in Sleep Disorders and Sleep Health for Women

2020 ◽  
Vol 4 ◽  
pp. 247028972094187
Author(s):  
Jennifer L. Marsella ◽  
Katherine M. Sharkey
Keyword(s):  
Sleep Disorders ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Future Research ◽  
Sex And Gender ◽  
Sleep Health ◽  
Sleep Behavior ◽  
Obstructive Sleep ◽  
And Gender ◽  
The Impact

Over the past 3 decades, significant strides have been made in the field of sleep medicine for women. The impact of sex and gender on sleep health and sleep disorders received little attention in the early 1990s, but driven by policies ensuring inclusion of women in medical research, more recent studies have identified sex differences in sleep and investigated gender differences in sleep disorders. Nevertheless, disparities remain: diagnosis of sleep disorders, such as obstructive sleep apnea, narcolepsy, and rapid eye movement (REM) sleep behavior disorder are often delayed and underdiagnosed in women. Future research should continue to examine how biological sex and identity across the gender spectrum influence sleep health and sleep disorders, allowing for more personalized health care for all patients.

scholarly journals Sex and Gender Interactions on the Use and Impact of Recreational Cannabis

2020 ◽  
Vol 17 (2) ◽  
pp. 509 ◽  
Author(s):  
Lorraine Greaves ◽  
Natalie Hemsing
Keyword(s):  
Cannabis Use ◽  
Public Health Issue ◽  
Sex And Gender ◽  
Related Factors ◽  
Precise Integration ◽  
Routes Of Administration ◽  
Wide Range ◽  
Scoping Reviews ◽  
And Gender ◽  
The Impact

Cannabis is the second most frequently used substance in the world and regulated or legalized for recreational use in Canada and fourteen US states and territories. As with all substances, a wide range of sex and gender related factors have an influence on how substances are consumed, their physical, mental and social impacts, and how men and women respond to treatment, health promotion, and policies. Given the widespread use of cannabis, and in the context of its increasing regulation, it is important to better understand the sex and gender related factors associated with recreational cannabis use in order to make more precise clinical, programming, and policy decisions. However, sex and gender related factors include a wide variety of processes, features and influences that are rarely fully considered in research. This article explores myriad features of both sex and gender as concepts, illustrates their impact on cannabis use, and focuses on the interactions of sex and gender that affect three main areas of public interest: the development of cannabis use dependence, the impact on various routes of administration (ROA), and the impact on impaired driving. We draw on two separate scoping reviews to examine available evidence in regard to these issues. These three examples are described and illustrate the need for more comprehensive and precise integration of sex and gender in substance use research, as well as serious consideration of the results of doing so, when addressing a major public health issue such as recreational cannabis use.

Sign in / Sign up

Export Citation Format

Share Document