Rapid separation of isomeric perfluoroalkyl substances by high-resolution differential ion mobility mass spectrometry

2019 ◽  
Vol 1058 ◽  
pp. 127-135 ◽  
Author(s):  
Ezaz Ahmed ◽  
K.M. Mohibul Kabir ◽  
Huixin Wang ◽  
Dan Xiao ◽  
John Fletcher ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Ion Mobility ◽  
Perfluoroalkyl Substances ◽  
Ion Mobility Mass Spectrometry ◽  
Rapid Separation

High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids

The Analyst ◽  
2015 ◽  
Vol 140 (20) ◽  
pp. 6904-6911 ◽  
Author(s):  
M. Groessl ◽  
S. Graf ◽  
R. Knochenmuss
Keyword(s):  
Mass Spectrometry ◽  
Double Bond ◽  
High Resolution ◽  
Ion Mobility ◽  
Biological Samples ◽  
Drift Tube ◽  
Acyl Chain ◽  
Ion Mobility Mass Spectrometry

Separation and identification of isomeric species is a major challenge in lipidomics. Herein, we demonstrate that lipid isomers that differ only in position of the acyl chain, position of the double bond or double bond geometry can be distinguished using drift-tube ion mobility-mass spectrometry, even in complex biological samples.

Characterization of simple isomeric oligosaccharides and the rapid separation of glycan mixtures by ion mobility mass spectrometry

2010 ◽  
Vol 298 (1-3) ◽  
pp. 119-127 ◽  
Author(s):  
Jonathan P. Williams ◽  
Megan Grabenauer ◽  
Richard J. Holland ◽  
Catherine J. Carpenter ◽  
Mark R. Wormald ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Rapid Separation
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