Phenotype and genotype characteristics of 58 patients showing a prolonged effect of succinylcholine: A four-year experience

2021 ◽  
Vol 40 (2) ◽  
pp. 100847
Author(s):  
Clément Millet ◽  
Benoît Plaud ◽  
Hervé Delacour
Keyword(s):  

Efficiency of combination of soil herbicide Command (CE 0.02 ml/m2) and growth stimulators Melafen and Emistim S for tobacco seedling growing in sheltered ground has been studied. Before studies inhibition properties of herbicide on first stage of tobacco growing were found. For decreasing effect of herbicide ’s depression and increasing growing processes researches during greenhouse and field stages have been carried. It has been found that soaking seeds in solution of growth stimulator Melafen (concentration 0.05 %) and Emistim S (concentration 0.00001 %) during 3 hours in combination with further treatments on basic stages of seedling development (cotyledon and ready for transplanting before pulling out) led not only to decreasing toxic effect of herbicide but also increasing qualitative properties of tobacco plants. Growth stimulators led to increasing length of plants from collar to growing point by 46-62 %, to end of tips - by 20-35 %, above ground plant mass - by 42 - 86 %, root mass - by 32 %. It was also noticed 28 - 36 % increasing outcome of standard seedlings from m2 in time of transplanting. Due to prolonged effect of Melafen and Emistim S seedlings transplanted into field were with increased surviving properties. Later, due to increased growing rate it was noticed increasing leaf area by 9-18 % and productivity - by 16-24 %. Economic effect due to utilizing growth stimulators Melafen and Emistim S during seedling stage reaches 360 and 470 rubles/m2 and during field stage - 66 and 98 th.rubles/ha respectively. Offered elaboration can be utilized for protecting systems of different agricultural plants where utilizing soil herbicides is recommended. Also quality of cured tobacco grown with stimulators had been improved.


2000 ◽  
Vol 88 (1) ◽  
pp. 165-172 ◽  
Author(s):  
L. Perry Koziris ◽  
William J. Kraemer ◽  
Scott E. Gordon ◽  
Thomas Incledon ◽  
Howard G. Knuttgen

This investigation was conducted to determine the effect of postexercise ethanol intoxication (21.97 ± 1.09 mmol/l blood) on the response of selected aspects of the neuroendocrine system to a resistance exercise (Ex) session. Nine resistance-trained men (25.0 ± 1.4 yr, 179.4 ± 3.4 cm, 79.7 ± 3.3 kg) were used to compare three 3-day treatments: control, Ex, and ethanol after exercise (ExEt). Blood was collected serially from an antecubital vein before exercise, immediately after exercise, and for pooled analysis at 20–40 (2 samples), 60–120 (4 samples), and 140–300 (9 samples) min after exercise on day 1 and in the morning (2 samples each) on days 2 and 3. Ethanol did not increase circulating epinephrine, norepinephrine, or cortisol concentration (Cort) above Ex elevations. At 60–120 min, only ExEt Cort was greater than control Cort. Concentrations of testosterone, luteinizing hormone, and corticotropin were not affected by either treatment. It is concluded that, although this blood ethanol concentration is insufficient to acutely increase Cort above that caused by Ex alone, it appears that ethanol may have a prolonged effect beyond the Ex response. This blood ethanol concentration does not further stimulate the sympathoadrenal system during the postexercise response.


Author(s):  
M.A. Shabalin ◽  
◽  
A.V. Deryugina ◽  
V.V. Nazarova ◽  
E.A. Gracheva ◽  
...  

Introduction. Nowadays, it has been shown that one of the possible ways to increase the effectiveness of the treatment of malignant tumors is the use of combined treatment methods. Aim. To study the intensity of lipid peroxidation (LPO) and the activity of superoxide dismutase (SOD) in hyperthermia against the background of bee venom in the blood of tumor-bearing rats. Materials and methods. The experimental animals were divided into 5 groups: 1st — intact; 2nd — control (tumor-bearing animals (PS-1 tumor strain) with intraperitoneal (IP) administration of saline solution); 3rd, 4th and 5th groups — tumor-bearing animals with IP administration of 0.5 ml of bee venom against the background of hyperthermia 42, 43 and 44°C respectively. The content of diene and triene conjugates, Schiff bases (SB) and SOD activity in the blood of animals was determined. Results. From the 1st day after the end of the experiment, a statistically significant decrease in triene conjugates was recorded in all experimental groups compared to the control group. SB decreased on the 1st–7th day after the end of the experiment with the action of hyperthermia 42°C and bee venom, on the 7th–28th day — with the action of hyperthermia 43°C and bee venom, and on the 28th day — with the action of bee venom and hyperthermia 44°C, which was accompanied by an increase in SOD activity from the 7th day in all experimental groups compared to the control group. Conclusion. Hyperthermia in combination with the action of bee venom causes a decrease in lipid peroxidation products and an increase in antioxidant activity in the blood of tumor-bearing rats. The most effective action, in our opinion, is the use of bee venom against the background of hyperthermia of 43°C, at which a prolonged effect is recorded both with respect to a decrease in the concentration of SB and an increase in the activity of SOD.


2019 ◽  
Vol 3 (12) ◽  
pp. 471-474
Author(s):  
Adinda Chairunnisa ◽  
Prastiya Indra Gunawan ◽  
Isti Suharjanti

Background: Febrile seizures are seizures that often occur in children, usually of a non-hazardous nature and do not have a prolonged effect. Febrile seizures most often occur in children under five years of age and are reported to occur in 2-5% of the pediatric population. Febrile seizures are categorized as simple, complex and plus febrile seizures. In some patients, EEG is needed to ascertain whether a true febrile seizure occurs. Objective: This study aims to determine the EEG pattern in recurrent febrile seizure patients at the Child Inpatient Installation of Dr. Soetomo Surabaya. Method: This study used a retrospective descriptive method with medical record instruments. Results: This study showed that of 46 recurrent febrile seizures, only 21 patients could see the EEG results. Of the 18 patients with complicated febrile seizures there were 27.78% abnormal and 72.22% normal. One simple febrile seizure patient obtained a normal EEG result. Of the two patients with febrile seizures plus 50% abnormal results and 50% normal results. Conclusions: The EEG pattern in patients with recurring complex febrile seizure obtains the most abnormal result. Keywords: recurrent febrile seizure; electroencephalography; prevalence


Author(s):  
T. Medvedeva ◽  
T. Natalchuk ◽  
K. Suprun ◽  
I. Ryaba ◽  
N. Triapitsyna

Most of promising raspberry varieties need to be heal from complex viral infections. Development of the most standardized and universal plant healing methods — one of the actual tasks of biotechnology works for raspberries plant material production. The decrease of virus concentration in explants of some promising hybrid forms and varieties of raspberry affected by complex viral infection were analyzed with semi quantitative LIA method after explants treatment with ribavirin. Rated the therapeutic, toxic and prolonged effect of ribavirin for elimination of four viruses were evaluated. It was revealed universal peculiarities for chemotherapy of raspberries shoots using this virocide.


1995 ◽  
Vol 56-63 ◽  
pp. 35-35
Author(s):  
C. Gasperini ◽  
T. Koudriatseva ◽  
C. Pozzilli ◽  
S. Bastianello ◽  
A. Colleluon ◽  
...  

2018 ◽  
Vol 159 (36) ◽  
pp. 1475-1482 ◽  
Author(s):  
Szonja Vingender ◽  
László Restár ◽  
Krisztián Benedek Csomó ◽  
Péter Schmidt ◽  
Péter Hermann ◽  
...  

Abstract: Introduction: Derangement of the temporomandibular joint complicates everyday life, due to the masticatory malfunction and the continuous pain sensation of the head and facial region. The therapy is multidisciplinary and varying. In case of the inefficiency of conservative therapy, minimally invasive intervention is needed with intraarticular injection. Aim: The aim of our study was to examine whether hyaluronic acid injection is more beneficial compared to corticosteroid in 37 joints. We also examined whether the efficacy of the therapy is influenced by hyaluronic acid molecular weight and the used protocol. Method: Wilkes stage, maximal mouth opening and the Visual Analogue Scale were determined pre-operatively and 6 months later. Corticosteroid application was performed once, hyaluronic acid was injected on a weekly bases 3 times in a row, by use of low (6–10 × 105 dalton) or high molecular weight (24–36 × 105 dalton) preparations. Results: The medical state of the patients treated with corticosteroid temporarily improved, but the symptoms returned. Due to hyaluronic acid treatment, significant improvement was revealed in all parameters (pwilkes<0.0001; pmouth-opening = 0.0002; pVAS<0.0001). There was no significant relapse (T = 2.05). The third administration of hyaluronic acid resulted in a significant improvement of the Visual Analogue Scale compared to the first and second injection (T3.–1. = 20.37; T3.–2. = 9.57). Conclusions: Comparing the two agents we can state that hyaluronic acid was significantly more effective and its application for three times seems to be the most effective treatment decreasing the symptoms. The high molecular weight solution was more effective in increasing mouth opening. In contrast to hyaluronic acid, corticosteroid had no prolonged effect in higher Wilkes stages. Orv Hetil. 2018; 159(36): 1475–1482.


2019 ◽  
Vol 34 (12) ◽  
pp. 2192-2197 ◽  
Author(s):  
Andrew Carr ◽  
Stephen J Kerr ◽  
Robyn Richardson ◽  
Peter Ebeling ◽  
Nicholas Pocock ◽  
...  

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