scholarly journals Pattern of Electroencephalography in Recurrent Febrile Seizure Patient

2019 ◽  
Vol 3 (12) ◽  
pp. 471-474
Author(s):  
Adinda Chairunnisa ◽  
Prastiya Indra Gunawan ◽  
Isti Suharjanti
Keyword(s):  
Medical Record ◽  
Febrile Seizure ◽  
Pediatric Population ◽  
Febrile Seizures ◽  
Simple Complex ◽  
Abnormal Result ◽  
Prolonged Effect ◽  
Febrile Seizures Plus ◽  
Descriptive Method ◽  
Eeg Pattern

Background: Febrile seizures are seizures that often occur in children, usually of a non-hazardous nature and do not have a prolonged effect. Febrile seizures most often occur in children under five years of age and are reported to occur in 2-5% of the pediatric population. Febrile seizures are categorized as simple, complex and plus febrile seizures. In some patients, EEG is needed to ascertain whether a true febrile seizure occurs. Objective: This study aims to determine the EEG pattern in recurrent febrile seizure patients at the Child Inpatient Installation of Dr. Soetomo Surabaya. Method: This study used a retrospective descriptive method with medical record instruments. Results: This study showed that of 46 recurrent febrile seizures, only 21 patients could see the EEG results. Of the 18 patients with complicated febrile seizures there were 27.78% abnormal and 72.22% normal. One simple febrile seizure patient obtained a normal EEG result. Of the two patients with febrile seizures plus 50% abnormal results and 50% normal results. Conclusions: The EEG pattern in patients with recurring complex febrile seizure obtains the most abnormal result. Keywords: recurrent febrile seizure; electroencephalography; prevalence

Identification of a Novel Nonsense Variant in the SCN1A Gene that Causes Febrile Seizure Disorder

2017 ◽  
Vol 16 (04) ◽  
pp. 236-238
Author(s):  
Nabila MarchoudI ◽  
Abdelfettah Rouissi ◽  
Jamal Fekkak ◽  
Farah Jouali
Keyword(s):  
Febrile Seizure ◽  
Febrile Seizures ◽  
Seizure Disorder ◽  
Gene Encoding ◽  
Seizure Disorders ◽  
Severe Myoclonic Epilepsy ◽  
Epilepsy Gene ◽  
Generalized Epilepsy ◽  
Febrile Seizures Plus ◽  
Scn1a Gene

AbstractThe SCN1A gene, encoding for the voltage-gated sodium channel Nav1.1, is the most clinically relevant epilepsy gene, with most mutations having been documented in a spectrum of epilepsy syndromes, ranging from the relatively benign generalized epilepsy with febrile seizures plus (GEFS+) to severe myoclonic epilepsy in infancy (SMEI), and other rare febrile seizure disorders. To date, more than 1,250 mutations in SCN1A have been linked to epilepsy. In this case, we describe a novel nonsense pathogenic variant (NM_001202435.1; c.327C > G) in SCN1A in a 10-month Moroccan infant with febrile seizure disorder.

scholarly journals Association between Foramen Size and Febrile Seizure Status in the Pediatric Population: A Two-Center Retrospective Analysis

2020 ◽  
Vol 11 (03) ◽  
pp. 430-435
Author(s):  
Peyton Presto ◽  
Preston D’Souza ◽  
Avery Kopacz ◽  
Keith A. Hanson ◽  
Laszlo Nagy
Keyword(s):  
Risk Factor ◽  
Febrile Seizure ◽  
Normal Population ◽  
Pediatric Population ◽  
Strong Association ◽  
Febrile Seizures ◽  
Trauma Patients ◽  
Brain Cooling ◽  
Emissary Vein ◽  
Parietal Foramen

Abstract Objective Febrile seizures have been shown to occur in 2 to 5% of children between the ages of 6 months and 5 years, making them the most common seizures of childhood. Multiple risk factors for febrile seizures have been identified; however, no investigation has been conducted to explore foramen size and associated venous drainage as a potential risk factor for experiencing febrile seizures. Of particular interest are the parietal foramen and the condylar canal, which conduct the parietal emissary vein and the occipital emissary vein, respectively. Emissary veins lack valves, allowing them to play a crucial role in selective brain cooling via a bidirectional flow of blood from the head’s evaporating surface. Narrowed cranial apertures conducting these veins may lead to reduced cerebral venous outflow and delayed brain cooling, creating favorable conditions for a febrile event. This study seeks to explore the association between cranial aperture area and febrile seizure status. Methods A retrospective cross-sectional medical record review study from January 2011 to December 2017 was conducted at a 500-bed academic hospital and a 977-bed private hospital in Lubbock, Texas, United States. A total of 101 complex febrile seizure patients were compared with a similarly aged group of 75 trauma patients representing the normal population. Parietal foramen area and condylar canal area were electronically measured and defined as having “normal” or “below normal” area. Statistical Analysis Independent t-tests were used to compare foramen and canal areas by febrile seizure status. Logistic regression analyses were conducted to determine the association of small cranial aperture area with febrile seizure status. Results Below normal parietal foramen area had a strong association with febrile seizures in our patient population. Male sex, white race, and complete vaccination status were also found to have significant associations with febrile seizure status. Conclusion Our findings indicated that narrowed parietal foramen may be considered as a risk factor for febrile seizure development.

scholarly journals Genetic epilepsy with febrile seizures plus – an overview

2021 ◽  
Vol 20 (1) ◽  
pp. 21-27
Author(s):  
Madalina Radu ◽  
◽  
Eugenia Roza ◽  
Daniel Mihai Teleanu ◽  
Raluca Ioana Teleanu ◽  
...  
Keyword(s):  
Febrile Seizure ◽  
De Novo ◽  
Febrile Seizures ◽  
Alpha Subunit ◽  
Gamma Aminobutyric Acid ◽  
Voltage Gated ◽  
Genetic Epilepsy ◽  
Generalized Seizures ◽  
Gated Channel ◽  
Febrile Seizures Plus

Genetic epilepsy with febrile seizures plus (GEFS+) is characterized by a group of genetic epilepsies associated predominately with an autosomal dominant pattern, but also with de novo and autosomal-recessive inheritance, these last two found in a small number of cases. It was believed that GEFS+ is associated only with generalized seizures, but now the term “genetic epilepsy” is preferred because it has been demonstrated that GEFS+ is associated with both generalized and focal seizures. The “GEFS+ family” was defined as a family with more than two individuals with GEFS+ phenotypes, including at least one with febrile seizure or febrile seizure plus. The GEFS+ spectrum includes febrile seizures (FS), febrile seizures plus (FS+), myoclonic seizures, myoclonic-atonic seizures, absences seizures, focal or generalized seizures. The genetic mutations responsible for inhibitor-excitatory imbalance in neurons network were found in sodium voltage-gated channel alpha subunit 1 (SCN1A), sodium voltage-gated channel beta subunit 1 (SCN1B), sodium voltage-gated channel alpha subunit 2 (SCN2A), sodium voltage-gated channel alpha subunit 9 (SCN9A), gamma-aminobutyric acid type A receptor subunit gamma 2 (GABRG2), which are the main gene in GEFS+ genotype.

Analisis Unsur Manajemen dalam Pengolahan Rekam Medis di Rumah Sakit TNI AU Lanud Roesmin Nurjadin

2018 ◽  
Vol 1 (1) ◽  
pp. 20-25
Author(s):  
Henny Maria Ulfa
Keyword(s):  
Medical Record ◽  
Medical Records ◽  
Processing Method ◽  
Qualitative Approach ◽  
Check List ◽  
Training Material ◽  
Patient Medical Record ◽  
Qualitative Descriptive ◽  
Material Element ◽  
Descriptive Method

Hospitals must conduct a medical record activities according to Permenkes NO.269 / MENKES / PER / III / 2008 about Medical Record, to achieve the purpose of medical record processing required 5 management elements are: man, money, material, machine, and method. The medical record processing that has been implemented at the Hospital TNI AU LANUD Roesmin Nurjadin that is coding, coding only done for BPJS patients whose conducted by the officer with education background of D3 nursing, it be impacted to the storage part is wrong save and cannot found patient medical record file because are not returned. The purpose of this research is to know the element of management in the processing of medical records at the Hospital TNI AU LANUD Roesmin Nurjadin. This research is done by Qualitative descriptive method, Qualitative approach, instrument of data collection of interview guidance, observation guidance, check list register, and stationery, number of informant 6 people with inductive way data analysis. The result of this research found that Mans elements only amounts to 2 people so that officers work concurrently and have never attended training, material element and machines elements of medical record processing not yet use SIMRS and tracer, while processing method elements follow existing habits and follow the policy of hospital that is POP organization. Keywords: Management elements, medical record processing

Mutation screening of three Chinese families with genetic epilepsy with febrile seizures plus

2011 ◽  
Vol 500 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Hua Lin ◽  
Jingyun Li ◽  
Mengyang Wang ◽  
Zheng Wang ◽  
Yuping Wang ◽  
...  
Keyword(s):  
Mutation Screening ◽  
Febrile Seizures ◽  
Chinese Families ◽  
Genetic Epilepsy ◽  
Febrile Seizures Plus

Just Say No!

PEDIATRICS ◽  
1990 ◽  
Vol 86 (4) ◽  
pp. 624-624
Author(s):  
JOHN M. FREEMAN
Keyword(s):  
Febrile Seizure ◽  
Febrile Seizures ◽  
National Institutes Of Health ◽  
Consensus Development ◽  
Consensus Development Conference ◽  
Focal Seizures ◽  
The Family ◽  
History Of ◽  
Neurologic Development

A seizure, even a febrile seizure, is terrifying to the family. Seeking reassurance that their child will not die and does not have epilepsy, parents turn to their physician. What is he or she to do? Often the physician prescribes medication "to prevent further seizures" and then reassures the family that the child will be fine if the medicine is given daily as directed. Both the recommendation and the reassurance are wrong. A Consensus Development Conference on Febrile Seizures held by the National Institutes of Health in 19801 concluded that they would only "consider" anticonvulsant prophylaxis when the child (1) had abnormal neurologic development, (2) had long or focal seizures, (3) had more than two seizures in 24 hours, (4) had a history of nonfebrile seizures in parent or sibling, or (5) was younger than 1 years of age.

The Association between Serum Sodium Levels and Febrile Seizures Recurrence: Is the Degree of Hyponatremia a Risk Factor?

2021 ◽  
Author(s):  
Esma Keleş Alp ◽  
Ahmet Midhat Elmacı
Keyword(s):  
Serum Sodium ◽  
Medical Records ◽  
Febrile Seizure ◽  
Serum Sodium Level ◽  
Febrile Seizures ◽  
Lower Sensitivity ◽  
Operating Characteristics ◽  
Serum Electrolyte ◽  
Optimal Cutoff ◽  
Characteristics Analysis

AbstractFebrile seizures are common disorders in childhood. We evaluated the serum electrolyte levels and the associated factors in children with single and recurrent febrile seizures in 24 hours period of hospitalization. The medical records of children who were clinically diagnosed with febrile seizures and hospitalized were retrospectively revealed and analyzed. Data were collected for children aged 1 to 6 years including demographic parameters and serum electrolyte levels. A total of 244 children were enrolled in the study in which 209 were diagnosed with single febrile seizures and 35 of them with recurrent febrile seizures. Serum sodium levels were significantly lower in children with recurrent febrile seizure (138.5 ± 2.38 and 134.2 ± 3.55, p < 0.001). Correlation analysis revealed that mild hyponatremia is associated with recurrence of febrile seizure within 24 hours. However, receiver-operating characteristics analysis for hyponatremia showed lower sensitivity (50.3%) and specificity (43.1%) values for optimal cutoff value of 133.5 mmol/L of serum sodium level. Our study suggested that serum sodium levels were significantly lower in children with recurrent febrile seizures. However, because of its lower sensitivity and specificity values, mild hyponatremia cannot be used as an indicator for febrile seizure recurrence.

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