Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy

2017 ◽  
Vol 48 ◽  
pp. 238-246 ◽  
Author(s):  
Wei Li ◽  
Dongfei Liu ◽  
Hongbo Zhang ◽  
Alexandra Correia ◽  
Ermei Mäkilä ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Colon Cancer ◽  
Cancer Therapy ◽  
Halloysite Nanotubes ◽  
Ph Responsive ◽  
Responsive Polymer ◽  
Delivery Platform ◽  
Microfluidic Assembly ◽  
Dual Drug

Microfluidic Assembly of Monodisperse Multistage pH-Responsive Polymer/Porous Silicon Composites for Precisely Controlled Multi-Drug Delivery

Small ◽  
2014 ◽  
Vol 10 (10) ◽  
pp. 2029-2038 ◽  
Author(s):  
Dongfei Liu ◽  
Hongbo Zhang ◽  
Bárbara Herranz-Blanco ◽  
Ermei Mäkilä ◽  
Vesa-Pekka Lehto ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Ph Responsive ◽  
Responsive Polymer ◽  
Microfluidic Assembly

Polymeric prodrugs conjugated with reduction-sensitive dextran–camptothecin and pH-responsive dextran–doxorubicin: an effective combinatorial drug delivery platform for cancer therapy

2016 ◽  
Vol 7 (25) ◽  
pp. 4198-4212 ◽  
Author(s):  
Dongling Cao ◽  
Jinlin He ◽  
Jiaying Xu ◽  
Mingzu Zhang ◽  
Lin Zhao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Activity ◽  
Ph Responsive ◽  
Delivery Platform ◽  
Stimuli Sensitive

Two types of stimuli-sensitive polymeric prodrugs for combinatorial cancer therapy have been prepared and found to exhibit favorable anticancer activity in vitro and in vivo.

scholarly journals Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy

2018 ◽  
Vol 9 ◽  
Author(s):  
Sangram Raut ◽  
Linda Mooberry ◽  
Nirupama Sabnis ◽  
Ashwini Garud ◽  
Akpedje Serena Dossou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Biological Barriers ◽  
Delivery Platform

Degradable polycaprolactone nanoparticles stabilized via supramolecular host–guest interactions with pH-responsive polymer-pillar[5]arene conjugates

2020 ◽  
Vol 11 (12) ◽  
pp. 1985-1997
Author(s):  
Peng Wei ◽  
Fabian H. Sobotta ◽  
Carolin Kellner ◽  
Damiano Bandelli ◽  
Stephanie Hoeppener ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Amphiphilic Polymers ◽  
Ph Responsive ◽  
Responsive Polymer ◽  
New Generation

Smart nano-carriers such as micelles, vesicles or nanoparticles constructed from amphiphilic polymers promise a new generation of drug delivery systems featuring localized and controlled release.

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

Construction of pH-responsive drug delivery platform with calcium carbonate microspheres induced by chitosan gels

2018 ◽  
Vol 44 (7) ◽  
pp. 7902-7907 ◽  
Author(s):  
Jingwei Wang ◽  
Yong Kong ◽  
Feng Liu ◽  
Dan Shou ◽  
Yongxin Tao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Carbonate ◽  
Ph Responsive ◽  
Delivery Platform

A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

2020 ◽  
Vol 8 (12) ◽  
pp. 3418-3429 ◽  
Author(s):  
Yongju He ◽  
Linjie Shao ◽  
Ibrahim Usman ◽  
Yao Hu ◽  
Anqiang Pan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Ph Responsive ◽  
Epr Effect ◽  
Large Size ◽  
Rapid Clearance ◽  
Tumor Accumulation ◽  
Dual Drug

A pH-responsive dissociable mesoporous silica-based cluster with efficient dual-drug co-delivery for combinational cancer therapy, tumor accumulation via its large size-favored EPR effect and rapid clearance by its acid-triggered dissociation.

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