Antibiotic Susceptibility Patterns for Community Acquired Methicillin- resistant Staphylococcus aureus Infections in a Veterans Administration Medical Center in Northwest Louisiana, 2005-2007

Recently, concern has increased regarding the spread of methicillin-resistant Staphylococcus aureus (MRSA) in the community. We studied 812 subjects from central Italy to establish the rates of nasal carriage of S. aureus, and antibiotic susceptibility patterns, in the community. The prevalence of S. aureus nasal carriage was 30.5%. Only one subject, with predisposing risk factors for acquisition, was identified as carrier of MRSA (prevalence of 0.12%). The presence of MRSA in the community of our area still appears to be a rare event. Among methicillin-susceptible S. aureus (MSSA) isolates, a surprisingly high rate (18%) of resistance to rifampin was observed.

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Methicillin-resistant Staphylococcus aureus in Veterans Administration Medical Centers

Infection Control ◽

10.1017/s0195941700065929 ◽

1987 ◽

Vol 8 (5) ◽

pp. 191-194 ◽

Cited By ~ 46

Author(s):

Laurel C. Preheim ◽

David Rimland ◽

Marvin J. Bittner

Keyword(s):

United States ◽

Staphylococcus Aureus ◽

Nursing Homes ◽

Methicillin Resistant Staphylococcus Aureus ◽

The United States ◽

Veterans Administration ◽

Success Rates ◽

Methicillin Resistant ◽

Administration Medical ◽

Medical Centers

AbstractTo determine the frequency of isolation of methicillin-resistant Staphylococcus aureus (MRSA) at Veterans Administration Medical Centers, 163 hospitals were surveyed; 137 responded. Between 1975 and 1984, the number of Veterans Administration Medical Centers with known MRSA increased from 3 to 111. This increase was geographically widespread and occurred in hospitals of all sizes. In Veterans Administration Medical Centers, isolation policies for MRSA-infected patients were (% of hospitals using): strict (19%), contact (52%), site-related (28%), no isolation (1%). For patients colonized with MRSA policies were: strict (15%), contact (44%), site-related (35%), and no isolation (6%). Only 41% of Veterans Administration Medical Centers reported discharging known MRSA-colonized patients to nursing homes. Most attempts to eradicate MRSA carriage used trimethoprim-sulfamethoxazole plus rifampin with or without bacitracin ointment; success rates were low. MRSA incidence is increasing at Veterans Administration Medical Centers across the United States. Improved regimens to eliminate MRSA carriage are needed.

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Emergence of Nosocomial Methicillin-Resistant Staphylococcus aureus and Therapy of Colonized Personnel during a Hospital-Wide Outbreak

Infection Control ◽

10.1017/s0195941700065802 ◽

1987 ◽

Vol 8 (4) ◽

pp. 145-150 ◽

Cited By ~ 38

Author(s):

Alfred E. Bacon ◽

Karen A. Jorgensen ◽

Kenneth H. Wilson ◽

Carol A. Kauffman

Keyword(s):

Staphylococcus Aureus ◽

Methicillin Resistant Staphylococcus Aureus ◽

Medical Center ◽

Carrier State ◽

Control Measures ◽

Veterans Administration ◽

Outbreak Strain ◽

Methicillin Resistant ◽

Infection Control Measures ◽

Ann Arbor

AbstractAt the Ann Arbor Veterans Administration Medical Center, 30 patients over a 6-month period became nosocomially infected or colonized by methicillin-resistant Staphylococcus aureus. Immediate institution of strict infection control measures, in conjunction with surveillance cultures of personnel and treatment of carriers, did not limit spread of the outbreak strain of MRSA. Multiple nonoutbreak strains, phenotypically exhibiting heteroresistance, were also uncovered. Thirteen hospital personnel were identified as MRSA carriers. Trimethoprim-sulfamethoxazole (TMP-SMX) and rifampin initially eradicated the carrier state, documented by anterior nares cultures in 13 courses of treatment in 11 employees. However, three employees were recolonized, one at one month, one at both one and four months, and one at four months. Treatment of the carrier state reservoir among personnel appeared to have no effect on the emergence and spread of nosocomial MRSA.

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