Periodontal ligament enhancement after orthodontic movement in third molars: Proliferative stimulus or increased periodontal ligament space?

ABSTRACT Introduction: The epithelial rests of Malassez (ERM) represent a group of cells in the periodontal ligament classically consisting of latent or quiescent structures associated with pathological processes. However, recent evidence shows that these structures cannot be considered only as cellular debris. The ERM is a major tissue structure, with functions in maintaining the homeostasis of periodontal tissue, including the maintenance of orthodontic movement. Objective: The present literature review aims at presenting the potential functions of ERM, with emphasis on orthodontic movement and the functional structure of the periodontium. Conclusion: ERM cells have a functional activity in modulation of orthodontic movement, trough their potential for differentiation, maintenance functions and the capacity of repairing periodontium.

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Characterization and Cytotoxicity Analysis of a Ciprofloxacin Loaded Chitosan/Bioglass Scaffold on Cultured Human Periodontal Ligament Stem Cells: a Preliminary Report

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2016.052 ◽

2016 ◽

Vol 4 (3) ◽

pp. 461-467 ◽

Cited By ~ 3

Author(s):

Maha I. Abdelfattah ◽

Sherine A. Nasry ◽

Amani A. Mostafa

Keyword(s):

Stem Cells ◽

Bioactive Glass ◽

Periodontal Ligament ◽

Cell Number ◽

Proliferation Rate ◽

Blue Dye ◽

Third Molars ◽

Periodontal Ligament Stem Cells ◽

Significant Difference ◽

One Way Anova

AIM: The aim of this study was to analyze the cytotoxicity of ciprofloxacin (CIP) loaded on chitosan bioactive glass scaffold on human periodontal ligament stem cells (PLSCs) in vitro.MATERIALS AND METHODS: PLSCs obtained from human third molars, cultures treated with medium containing 15 x 15 mm chitosan/bioactive glass scaffolds without/with different concentration 0, 5, 10, and 20 % of CIP. A total of 15 x 10^3 cells were plated in 6 well plates. The attached cells of each group were harvested from the plates after 1, 4 and 8 days of culture to detect the viability of cells. The cell number was determined using a hemocytometer and the trypan blue dye-exclusion assay. Data was analyzed using normality using Shapiro-Wilk test. Comparisons between groups were made using One-way ANOVA complemented by Tukey's test.RESULTS: When comparing the proliferation rate of cells in the four groups, no statistically significant difference was found (P = 0.633). With regards to cell viability, no statistical difference was found between the 0, 5, and 10 % CIP concentrations, while the 20 % CIP concentration demonstrated the least viability with a high statistically significant difference (P = 0.003).CONCLUSION: Twenty percentages CIP demonstrated the least proliferation rate and viability.

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The chronology of the radiographic visibility of the periodontal ligament and the root pulp in the lower third molars

Science & Justice ◽

10.1016/j.scijus.2017.03.004 ◽

2017 ◽

Vol 57 (4) ◽

pp. 257-261 ◽

Cited By ~ 10

Author(s):

M. Timme ◽

W.H. Timme ◽

A. Olze ◽

C. Ottow ◽

S. Ribbecke ◽

...

Keyword(s):

Periodontal Ligament ◽

Third Molars

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Periodontal ligament enhancement in mesio-angulated impaction of third molars after orthodontic tooth movement: A prospective cohort study

American Journal of Orthodontics and Dentofacial Orthopedics ◽

10.1016/j.ajodo.2019.08.011 ◽

2020 ◽

Vol 158 (4) ◽

pp. 495-504

Author(s):

Pattarin Promchaiwattana ◽

Boonsiva Suzuki ◽

Suttichai Krisanaprakornkit ◽

Eduardo Yugo Suzuki

Keyword(s):

Cohort Study ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Periodontal Ligament ◽

Tooth Movement ◽

Orthodontic Tooth Movement ◽

Third Molars

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Advancements in the knowledge of induced tooth movement: idiopathic osteosclerosis, cortical bone and orthodontic movement

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512012000400004 ◽

2012 ◽

Vol 17 (4) ◽

pp. 12-16 ◽

Cited By ~ 4

Author(s):

Alberto Consolaro ◽

Renata Bianco Consolaro

Keyword(s):

Cortical Bone ◽

Periodontal Ligament ◽

Tooth Movement ◽

No Reduction ◽

Root Resorption ◽

Slight Degree ◽

Risk Of Death ◽

Cortical Areas ◽

Orthodontic Movement ◽

Applied Forces

Moving teeth orthodontically through the dense trabecular bone and cortical areas may require a reduction in the intensity and/or concentration of the applied forces. In part, the orthodontic applied forces are dissipated and reduced by bone deflection, which normally occurs by a slight degree of elasticity of bone tissue in normal conditions. In areas of dense trabecular and in cortical bone this deflection should be insignificant or nonexistent. If there is no reduction in the intensity of the forces in these mentioned regions, the entire force will focus on the structure of the periodontal ligament, increasing the risk of death of cementoblasts, hyalinization and root resorption. Further studies could assess the prevalence of these consequences in populations selected for this purpose, so that would no longer be randomly observed notes.

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The action of corticosteroids on orthodontic tooth movement: a literature review

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512012000600005 ◽

2012 ◽

Vol 17 (6) ◽

pp. 20e1-20e5

Author(s):

Luegya Amorim Henriques Knop ◽

Ricardo Lima Shintcovsk ◽

Luciana Borges Retamoso ◽

Ana Maria Trindade Grégio ◽

Orlando Tanaka

Keyword(s):

Periodontal Ligament ◽

Orthodontic Treatment ◽

Tooth Movement ◽

Orthodontic Tooth Movement ◽

Sterile Inflammation ◽

X Rays ◽

Pharmacological Agents ◽

Orthodontic Movement ◽

Multiple Reactions ◽

Biomechanical Forces

INTRODUCTION: Tooth movement is initially characterized by an acute sterile inflammation, followed by sequential multiple reactions in the periodontal ligament in response to biomechanical forces. Pharmacological agents such as corticosteroids may affect the course of orthodontic movement. Scientific studies show antagonistic actions of these drugs on bone resorption during tooth movement. OBJECTIVE: To review the literature about the effect of corticosteroids on orthodontic tooth movement. CONCLUSION: Patients should be questioned regarding the use of these drugs in the orthodontic practice and for those who use them, the orthodontic treatment should be differentiated, with longer intervals between visits and periodic X-rays due to the delay in bone formation observed in some scientific studies.

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