Serum level of zinc in asthmatic patients: A case–control study

2014 ◽  
Vol 42 (1) ◽  
pp. 19-21 ◽  
Author(s):  
G. Khanbabaee ◽  
A. Omidian ◽  
F. Imanzadeh ◽  
F. Adibeshgh ◽  
M. Ashayeripanah ◽  
...  
Author(s):  
D V K Irugu ◽  
A Singh ◽  
H Yadav ◽  
H Verma ◽  
R Kumar ◽  
...  

Abstract Objectives This study aimed to evaluate serum otolin-1 levels in patients with benign paroxysmal positional vertigo and to compare these levels with healthy individuals. Method This was a case-control study. After obtaining institutional ethical committee clearance, the serum level of otolin-1 was calculated in adult individuals (18–75 years old) who were divided into group 1 (patients presenting with benign paroxysmal positional vertigo) and group 2 (healthy patients without benign paroxysmal positional vertigo as the control group). Data analysis was carried out to compare the serum levels in the cases and controls. A p-value less than 0.05 was considered significant. Results A total of 70 age-matched individuals (cases, n = 40; controls, n = 30) were included in the study. The mean serum level of otolin-1 was 636.8 pg/ml (range, 259–981 pg/ml) in the group of patients with benign paroxysmal positional vertigo and 236.2 pg/ml (range, 189–370 pg/ml) in the control group. The difference was statistically significant (p = 0.0000). Conclusion The serum levels of otolin-1 in patients with benign paroxysmal positional vertigo are significantly higher compared with individuals without benign paroxysmal positional vertigo.


BioSight ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 6-10
Author(s):  
Hira Liaquat ◽  
Tabinda Najeeb ◽  
Rahima Aftab ◽  
Tayyaba Kazmi ◽  
Padma Rathore ◽  
...  

Background: Comparison of pulmonary function tests (PFTs) were achieved between asthmatic case and Controls. Materials & Methods: Case-control study conducted at Baqai Medical University (50 cases and 50 control). PFTs in both the participants were estimated by spirometry; FEC, FEV1 and their ratios were estimated. Results: According to the findings all spirometric values were lower in asthmatic patients as compared to healthy subjects. Moreover the asthamatic subjects had lower lung values when compared with healthy subjects. Conclusion: The current study evaluated spirometric values in asthmatic patients in Gadap area. This study's findings can be applied to the treatment of asthma in people of all ages.


2008 ◽  
Vol 29 (10) ◽  
pp. 921-926 ◽  
Author(s):  
Hilary M. Babcock ◽  
Liana R. Merz ◽  
Erik R. Dubberke ◽  
Victoria J. Fraser

Background.The symptoms of influenza infection in outpatients are well described. The Centers for Disease Control and Prevention (CDC) definition of an influenza-like illness (ILI) includes fever and cough or sore throat. Few data exist on the clinical presentation of influenza in hospitalized patients, which may be distinct from the clinical presentation of influenza in ambulatory patients because of underlying medical conditions and medications.Design.Retrospective case-control study.Setting.A 1,250-bed urban teaching hospital.Patients.A total of 369 patients were admitted to the general medicine wards during 3 consecutive influenza seasons (2001-2004): 123 case patients with laboratory-confirmed influenza that was diagnosed during routine medical care and 246 control patients with active surveillance culture results negative for influenza.Methods.Data on demographic characteristics, comorbidities, and signs and symptoms were obtained from a review of the medical records of the case and control patients. Analysis included stratified analysis and logistic regression.Results.Cough, coryza, sore throat, and fever were more common in patients with influenza infection. The CDC's definition of an ILI had a sensitivity of 43% and specificity of 86% in the study population, with a crude odds ratio (OR) of 4.7 (95% confidence interval [CI], 2.8-7.8). The sensitivity of the CDC's definition of an ILI decreased to 21% among asthmatic patients, who had similar rates of fever and/or ILI with or without influenza. By logistic regression, ILI was strongly associated with influenza infection in patients without asthma (adjusted OR, 7.5 [95% CI, 4.1-13.7]) but not in patients with asthma (adjusted OR, 1.1 [95% CI, 0.13-10]). The positive predictive value of an ILI in asthmatic patients was 50%.Conclusions.The CDC's definition of an ILI lacks sensitivity among hospitalized patients, and the presence of an ILI is not associated with influenza infection in asthmatic patients.


Author(s):  
Radwa El‐Sayed Mahmoud Marie ◽  
Aya Qamar Eldawla Mahmoud Abuzeid ◽  
Fadia M. Attia ◽  
Maha Mohamed Anani ◽  
Amal H. A. Gomaa ◽  
...  

2020 ◽  
Vol 21 (4) ◽  
Author(s):  
Afsaneh Sadeghian ◽  
Fateme Moghaddam ◽  
Khatereh Babakhani ◽  
Saba Shakarami ◽  
Pouneh Zolfaghari ◽  
...  

2020 ◽  
Author(s):  
Leta Adugna Geleta ◽  
Lelisa Sena Dadi ◽  
Alemayehu Atomsa Sona

Abstract BackgroundUncontrolled asthma is a notorious public health problem throughout the world despite the presence of effective treatments. Characterizing phenotypes of patients with uncontrolled asthma and searching for risk factors of uncontrolled asthma have been suggested as priority research agenda in the prevention of chronic respiratory diseases. This study aimed to identify the determinants of uncontrolled asthma.MethodsInstitution-based case-control study was conducted on asthmatic patients who were on follow-up at chest clinic of Jimma University Medical (JMC) from March to May, 2020. A total of 59 cases and 118 controls were included in the study. Logistic regression was employed to identify determinants of uncontrolled asthma. Adjusted odds ratios (AORs) with their corresponding confidence intervals (CI) were used to assess the strengths of association between uncontrolled asthma and its determinants at p values ≤ 0.05.ResultsAge of the patients [AOR: 2.78; 95% CI: 1.14, 6.81], age of the cases’ residential houses [AOR: 3.65; 95% CI: 1.30, 10.28], presence of pets within the houses [AOR: 2.78; 95% CI: 1.29, 5.96], having rhinitis [AOR: 3.34; 95% CI: 1.17, 9.52], past asthma exacerbation [AOR: 2.38, 95% CI: 1.05, 5.40], non-adherence to treatment [AOR: 2.81; 95% CI: 1.30, 6.08] and smoking [AOR: 7.09; 95% CI: 1.84, 27.33] were found to be determinants of uncontrolled asthma.ConclusionsUncontrolled asthma is resulted from multiple sociodemographic, environmental, clinical, and behavioral factors. Therefore, interventions targeting to improve asthma control should consider those factors comprehensively.


Sign in / Sign up

Export Citation Format

Share Document