Parental Vaccine Hesitancy and Association With Childhood Diphtheria, Tetanus Toxoid, and Acellular Pertussis; Measles, Mumps, and Rubella; Rotavirus; and Combined 7-Series Vaccination

AbstractVaccination is one of the most effective public health interventions today. However, there is a growing number of people who perceive vaccines as unsafe and unnecessary. Waning vaccine confidence threatens global immunization programmes, contributing to decreased immunization rates and outbreaks of vaccine-preventable diseases. We used a mixed-method approach surveying men and women of reproductive age and Focus Group Discussions with expectant mothers to understand maternal vaccine hesitancy within a rural setting of Kilifi County, Kenya. Of the 104 people surveyed, 70% of the participants were aware of the vaccine that expectant women receive and 26% stating that they know people in their community who have refused or were hesitant to take maternal vaccination. Reasons given for refusals include religion and rumors that have spread in the community that the tetanus toxoid vaccine was a family planning method. Stockout of the vaccine was identified as one of the healthcare factors affecting vaccine uptake. The majority of the respondents (84%) reported that they mainly trust a healthcare worker for vaccination information. Approximately 53% and 23% reported that they strongly agree or agreed, respectively, that vaccines for expectant women should be made compulsory. The availability of safe and effective maternal vaccines will only be beneficial if mothers choose to use them. Dissemination of accurate information and continuous engagement with the community members can build trust and confidence in vaccines.

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Delayed hypersensitivity to tetanus toxoid in man: in vivo and in vitro studies

Pathology ◽

10.3109/00313028309085161 ◽

1983 ◽

Vol 15 (4) ◽

pp. 369-372 ◽

Cited By ~ 15

Author(s):

Christine Johnson ◽

R.S. Walls ◽

A. Ruwoldt

Keyword(s):

Tetanus Toxoid ◽

In Vitro Studies ◽

Delayed Hypersensitivity

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The adjuvant effects of a tubercle bacillary lipid and lecithin: The immunization of mice by tetanus toxoid

Pathology ◽

10.3109/00313027009081209 ◽

1970 ◽

Vol 2 (3) ◽

pp. 209-216 ◽

Cited By ~ 3

Author(s):

A.W. Pound

Keyword(s):

Tetanus Toxoid ◽

Adjuvant Effects

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Sharp rise in vaccine hesitancy in a large and representative sample of the French population: reasons for vaccine hesitancy.

10.31234/osf.io/r8h6z ◽

2020 ◽

Author(s):

Anne-Sophie Hacquin ◽

Sacha Altay ◽

Emma de Araujo ◽

Coralie Chevallier ◽

Hugo Mercier

Keyword(s):

At Risk ◽

Educational Level ◽

Representative Sample ◽

Vaccine Hesitancy ◽

The Political ◽

French Population ◽

Sharp Rise ◽

Vaccine Refusal ◽

French People ◽

Nationally Representative

A safe and effective COVID-19 vaccine is our only hope to decisively stop the spread of the SARS-CoV-2. But a vaccine will only be fully effective if a significant share of the population agrees to get it. Five consecutive surveys of a large, nationally representative sample (N = 1000 for each wave) surveyed attitudes towards a future COVID-19 vaccine in France from May 2020 to October 2020. We found that COVID-19 vaccine refusal has steadily increased, reaching an all-time high with only 23% of participants willing to probably or certainly take a future COVID-19 vaccine in September 2020. Vaccine hesitant individuals are more likely to be women, young, less educated, to vote at the political extremes, to be dissatisfied with the government’s response to the COVID-19 crisis, and to feel less at risk of COVID-19. The reasons why French people would refuse to take the COVID-19 vaccine are similar to those offered for other vaccines, and these reasons are strikingly stable across gender, age and educational level. Finally, most French people declare they would not take the vaccine as soon as possible but would instead rather wait or not take it at all.

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Faculty Opinions recommendation of Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725387509.793509388 ◽

2015 ◽

Author(s):

Joyce Solheim

Keyword(s):

Dendritic Cell ◽

Tetanus Toxoid ◽

Dendritic Cell Vaccines

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COVID-19 Vaccine Hesitancy in the French Population of Working Age: A Randomized Experiment of Vaccine Characteristics

SSRN Electronic Journal ◽

10.2139/ssrn.3745198 ◽

2020 ◽

Author(s):

Michaël Schwarzinger ◽

Verity Watson ◽

Pierre Arwidson ◽

François Alla ◽

Stéphane Luchini

Keyword(s):

Vaccine Hesitancy ◽

Randomized Experiment ◽

French Population ◽

Working Age

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Qualitative Analysis of Underlying Factors Affecting Vaccine Hesitancy in Iran- A Study Protocol (Preprint)

10.2196/preprints.22746 ◽

2020 ◽

Author(s):

Salime Goharinezhad

Keyword(s):

Vaccine Coverage ◽

Deep Understanding ◽

World Health ◽

Vaccine Hesitancy ◽

Slight Reduction ◽

Cultural Variation ◽

Global Public Health ◽

Factors Affecting ◽

Wide Range ◽

Context Specific

BACKGROUND World Health Organization declared the vaccine hesitancy as a global public health threat in 2019. Since even a slight reduction in vaccine coverage rates can lead to a decrease in herd immunity, it is imperative to explore the underlying factors affecting vaccine hesitancy. in specific contexts, considering socioeconomic and cultural variation, to ensure interventions targeting hesitancy are well formulated and intervened. OBJECTIVE The main objective of this study is to identify underlying factors affecting vaccine hesitancy in Iran. METHODS A framework qualitative study will be conducted in the west of Tehran province in 2020. Participants in the study will be recruited hesitance-parents who extracted from the SIB system (an electronic health record in Iran) to maximize diversity. Interviews will be analyzed based on ''Determinants of Vaccine Hesitancy Matrix'' which developed by the WHO-SAGE Working Group. RESULTS deep understanding from the context-specific reasons for vaccine hesitancy cause to formulate better strategies to address them. The ultimate goal of this study is to inform future policies to increase the uptake of the vaccine in Iran. CONCLUSIONS This result of study will show variety opinions about vaccination among different types of socioeconomic and demographic households. The wide range of reasons related to vaccine hesitancy imply to more comprehensive, context-specific interventions. Today, the most important intervention issues focus on improving information about effectiveness and safety of vaccines, while other interventions for promoting vaccination is need to addressed.

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SARS-CoV-2: Vaccine Hesitancy among Underrepresented Racial and Ethnic Groups with HIV in Miami, Florida

Open Forum Infectious Diseases ◽

10.1093/ofid/ofab154 ◽

2021 ◽

Author(s):

Deborah L Jones ◽

Ana S Salazar ◽

Violeta J Rodriguez ◽

Raymond R Balise ◽

Claudia Uribe Starita ◽

...

Keyword(s):

Race And Ethnicity ◽

Cross Sectional Study ◽

Vaccine Uptake ◽

Vaccine Hesitancy ◽

Baseline Survey ◽

Advisory Group ◽

Medical Mistrust ◽

Cross Sectional ◽

Exact Test ◽

Novel Coronavirus

Abstract Background SARS-CoV-2 and HIV disproportionally affect underrepresented ethnoracial groups in the US. Medical mistrust and vaccine hesitancy will likely impact acceptability of SARS-CoV-2 vaccines. This study examined SARS-CoV-2 vaccine hesitancy among underrepresented ethnoracial groups with HIV and identified factors that may reduce vaccine uptake. Methods We conducted a cross-sectional study of adults ≥18 years with HIV residing in Miami, FL. Participants were invited to participate in the ACTION (A Comprehensive Translational Initiative on Novel Coronavirus) cohort study. A baseline survey was administered from April-August 2020 and followed by a COVID-19 vaccine hesitancy survey from August-November 2020. The COVID-19 vaccine hesitancy survey was adapted from the Strategic Advisory Group Experts survey. Comparisons by race and ethnicity were performed using the Freedman-Haltmann extension of Fisher’s exact test Results A total of 94 participants were enrolled, mean age 54.4 years, 52% female, 60% Black non-Latinx, and 40% non-Black Latinx. Black non-Latinx participants were less likely to agree that vaccinations are important for health when compared to non-Black Latinx (67.8% vs 92.1%, p=0.009), less likely to agree that vaccines are effective in preventing disease (67.8% vs 84.2%, p=0.029), less likely to believe that vaccine information is reliable and trustworthy (35.7% vs 71.1%, p=0.002), and less likely to believe vaccines were unnecessary because COVID-19 would disappear soon (11% vs 21%, p=0.049). Conclusion Medical mistrust, vaccine hesitancy and negative sentiments about SARS-CoV-2 vaccines are prevalent among underrepresented ethnoracial groups with HIV, particularly Black non-Latinx. Targeted strategies to increase vaccine uptake in this population are warranted.

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