Effect of the Metabolic Syndrome on Outcomes in Patients Aged 50 Years With Acute Myocardial Infarction

2018 ◽  
Vol 122 (2) ◽  
pp. 192-198 ◽  
Author(s):  
Inna Kim ◽  
Min Chul Kim ◽  
Doo Sun Sim ◽  
Young Joon Hong ◽  
Ju Han Kim ◽  
...  
2018 ◽  
Vol 29 (2) ◽  
pp. 6-10
Author(s):  
Khan MMR ◽  
Sana NK ◽  
PM Basak ◽  
BC Sarker ◽  
M Akhtarul Islam ◽  
...  

Background: Metabolic syndrome confers the risk of developing acute myocardial infarction which is the most common form of coronary heart disease and the single most important cause of premature death worldwide. The frequency and association of different components of metabolic syndrome on AMI are not well understood and has not been well evaluated.Objective: The aim of this study was to assess the components of the metabolic syndrome and its association with AMI patients. This study will help in awareness building in reducing AMI by early detection of components of metabolic syndrome.Patients and methods: This was a prospective observational study consisted of 325 AMI patients who were aged >20 years. Patients with first time AMI arriving in CCU of Rajshahi medical college during the period of 2012-2014, were included. Data were collected through interview, clinical examination, and laboratory tests within 24 hrs of AMI. Five components of metabolic syndrome were defined according to criteria set by modified NCEP ATP III (according to ethnic variation).Results: In AMI patients (n=325), no metabolic components were in 24 (7.4%) patients, one in 53 (16.3%), 2 components in 91(28.0%), 3 components were in 61(18.8%), 4 in 67(20.6%) and all 5 components were in 29 (8.9%) patients. In this study, there was no component in 7.4% of AMI patients, at least 1 component was 92.6%, at least 2 components were 76.3%, at least 3 components were 48.3%, at least 4 components were 29.5% and at least 5 components were 8.9%. The Metabolic syndrome was 48.3% (n=157). Among metabolic syndrome (≥3 components) in AMI (n=157, 48.3%) 4 components (20.6%) were more, next was 3 components (18.8%) and than 5 components (8.9%). Overall frequencies of components in acute myocardial infarction (n=325) were in order of abdominal obesity (54.8%) > high blood pressure (54.5%) > high FPG (54.2%) > Triglyceride (46.2%) and low HDL-C (46.2%) in acute myocardial infarction. Highest percentage was observed in abdominal obesity (54.8%) followed by high blood pressure (54.5%) and FPG (54.2%).TAJ 2016; 29(2): 6-10


2010 ◽  
Vol 144 (3) ◽  
pp. 450-451 ◽  
Author(s):  
Sandhir B. Prasad ◽  
Farzan Fahrtash ◽  
Yuvaraj Malaiapan ◽  
Ian T. Meredith ◽  
James Cameron

2018 ◽  
Vol 26 ◽  
pp. 74-78
Author(s):  
MMR Khan ◽  
Niranjan Kumar Sana ◽  
M Rais Uddin ◽  
M Rahman ◽  
M Zahirul Haque ◽  
...  

Introduction and objectives: A large proportion of patients with coronary disease have metabolic syndrome. The purpose of this research was to assess the association between the metabolic syndrome (MetS) and acute myocardial infarction in female patients.Methods: This was a case control study. Patients with a first time cardiac event of acute myocardial infarction (AMI) arriving in coronary care unit of Rajshahi Medical College Hospital, Rajshahi, Bangladesh during the period June 2013 to July 2014 were included. Metabolic syndrome and its five components were defined according to criteria set by Adult Treatment Plan III (NCEP ATP III) criteria. Blood sugars, triglycerides, HDL-C were measured within 24hrs of cardiac insult. Hypertension was defined as blood pressure ≥ 130/≥85 mmHg. Abdominal obesity measured by waist circumference which is defined for Asia-Pacific region as ≥ 80 cm for women.Results: Total 103 female patients were evaluated. Mean age was 54.28 ±11.78 and acute myocardial infarction was more in age group 50-59 (34%). More than 60% patients suffering from acute myocardial infarction was age group 40-60 years. The metabolic syndrome was present in 74 (71.8%) female patients with acute myocardial infarction and was more frequent in women than in men (71.8% vs 37.9%, P<.001). The most prevalent component was low HDL-C (n 76; 73.8%), followed by fasting plasma glucose level (n 73; 70.9%).Conclusions: The metabolic syndrome has a high prevalence in female patients with acute myocardial infarction. The most frequent components are low HDL-C levels and fasting plasma glucose level.TAJ 2013; 26: 74-78


2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Sandhir B. Prasad ◽  
Farzan Fahrtash ◽  
Yuvaraj Malaiapan ◽  
Ian T. Meredith ◽  
James Cameron

Background. We sought to determine and compare the prevalence of the Metabolic Syndrome (MS) in patients with acute myocardial infarction (AMI) utilizing the new International Diabetes Federation (IDF) definition with the older National Cholesterol Education Program (NCEP) definition. We also examined the clinical utility of MS in this context.Methods. A total of 107 consecutive patients with AMI were prospectively evaluated for MS. Fasting lipids obtained at admission and fasting glucose at discharge were used. A postdischarge folder audit verified rates of discharge coding and implementation of specific management strategies for MS.Results. Baseline patient characteristics included: mean age59±13years; males 80%; diabetes 19%; mean BMI29.7±8.4 kg/m2. MS prevalence was 54% by the IDF definition and 49% by the NCEP definition, with good agreement between definitions:κ=0.664,P<.001. Factors predictive of MS after multivariate analysis included: hypertension, fasting glucose, waist circumference, and serum HDL (allP<.05). Despite the high prevalence, MS was recognized at discharge in only 1 patient, and referral for exercise and/or weight-loss programs was undertaken in 5 patients.Conclusion. There is a high prevalence of MS utilizing contemporary definitions in patients with AMI: 54% by the IDF definition and 49% by NCEP criteria. Despite the high prevalence, MS was under-recognized and under-treated in this population.


2004 ◽  
Vol 10 (5) ◽  
pp. S159
Author(s):  
Takeno Masayoshi ◽  
Yasuda Satoshi ◽  
Otsuka Yoritaka ◽  
Kataoka Yu ◽  
Morii Isao ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
pp. 267
Author(s):  
Archana M. Uppin ◽  
Raju H. Badiger ◽  
Gayatri Sharma ◽  
Rishab Soni ◽  
Sowmya Parne ◽  
...  

Background: The Metabolic Syndrome (METS) is a specific clustering of cardiovascular risk factors in the same person (abdominal obesity, atherogenic dyslipidemia, elevated Blood Pressure (BP), Insulin Resistance (IR), and a proinflammatory state. A recent review of insulin resistance syndrome revealed a rapid escalation of this syndrome among Indians and the prevalence of predominant component of METS varies from region to region. Hence the present study was undertaken to assess the incidence of Metabolic Syndrome and prognosis of metabolic syndrome among acute myocardial infarction patients.Methods: A longitudinal study was carried among Acute myocardial infarction patients, who were admitted to ICCU of Shri. B. M. Patil Hospital and Research Centre, Bijapur during November 2009 to March 2011. Sample size was calculated using the formula: n=4pq/L2. Sample size required was 92. Descriptive statistics and Inferential statistics were used to analyse the results.Results: The incidence rate of METS among AMI in our study was 48.7%.  The complications were more common in METS group compared to those without METS groups. Recovery was better among those without METS group. There was a statistically significant association between complications and status of METS. The past history of DM was more common in METS. Hyperglycemia among the components of METS has strongest association with the outcome of death in patients of AMI.Conclusions: The metabolic syndrome is a highly prevalent condition among the patients with acute myocardial infarction and has detrimental impact on outcome Metabolic syndrome is also associated with a higher risk of severe heart failure and death.


2008 ◽  
Vol 17 ◽  
pp. S136 ◽  
Author(s):  
Sandhir Prasad ◽  
Farzan Fahrtash ◽  
Wai-ee Thai ◽  
Yuvaraj Malaiapan ◽  
James Cameron ◽  
...  

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