Effect of dietary vitamin A supplementation on growth performance, nutrient digestibility, serum parameters and liver histology of growing-furring male mink kits (Neovison vison)

To determine the effects of dietary vitamin A on the activity of the mixed function oxidase (MFO) system and on the susceptibility to 3-methylindole (3MI)-induced respiratory disease, goats were fed a high (supplemented with 12 000 IU retinyl palmitate/kg) or a low (no supplementation) vitamin A diet for 14 weeks. Four animals in each dietary group were then challenged with [14C]3MI. The remaining four animals served as controls. Enzyme assays were performed and severity of the 3MI-induced lung damage was scored. Consumption of the low vitamin A diet resulted in a significant reduction in the liver and lung contents of vitamin A; however, serum concentration of vitamin A was unaffected. High vitamin A supplementation did not alter the activity of the MFO system. Clinical signs, lung – body weight ratio and wet – dry weight ratio of the lungs of 3MI-infused goats were not significantly different; however, in the low vitamin A goats, the microscopic lesions such as the extent of alveolar epithelial hyperplasia were judged to be significantly more severe than those observed in the high vitamin A goats.

Download Full-text

Vitamin A deficiency among children younger than 5 y in India: an analysis of national data sets to reflect on the need for vitamin A supplementation

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqaa314 ◽

2020 ◽

Author(s):

G Bhanuprakash Reddy ◽

Raghu Pullakhandam ◽

Santu Ghosh ◽

Naveen K Boiroju ◽

Shalini Tattari ◽

...

Keyword(s):

Vitamin A ◽

Vitamin A Deficiency ◽

Public Health Problem ◽

Sample Survey ◽

Dietary Vitamin ◽

High Dose ◽

Serum Retinol ◽

Indian Children ◽

Vitamin A Supplementation ◽

National Prevalence

ABSTRACT Background Biochemical vitamin A deficiency (VAD) is believed to be a serious public health problem (low serum retinol prevalence >20%) in Indian children, justifying universal high-dose vitamin A supplementation (VAS). Objective To evaluate in Indian children younger than 5 y the risk of biochemical VAD from the Comprehensive National Nutrition Survey, as well as dietary vitamin A inadequacy and excess over the tolerable upper limit of intake (TUL) from national and subnational surveys, factoring in fortification and VAS. Methods Child serum retinol data, corrected for inflammation, were examined to evaluate national- and state-level prevalence of VAD. Simultaneously, dietary intakes from the National Sample Survey Office and the National Nutrition Monitoring Bureau were examined for risk of dietary vitamin A deficiency against its average requirement (AR) derived for Indian children. Theoretical estimates of risk reduction with oil and milk vitamin A fortification were evaluated along with the risk of exceeding the TUL, as well as when combined with intake from VAS. Results The national prevalence of biochemical VAD measured in 9563 children was 15.7% (95% CI: 15.2%, 16.3%), and only 3 states had prevalence significantly >20%. The AR of vitamin A was 198 and 191 µg/d for boys and girls; the risk of dietary inadequacy was ∼70%, which reduced to 25% with oil and milk fortification. Then, the risk of exceeding the TUL was 2% and 1% in 1- to 3-y-old and 4- to 5-y-old children, respectively, but when the VAS dose was added to this intake in a cumulative 6-mo framework, the risk of exceeding the TUL rose to 30% and 8%, respectively. Conclusion The national prevalence of VAD risk is below 20% in Indian children. Because there is risk of excess intake with food fortification and VAS, serious consideration should be given to a targeted approach in place of the universal VAS program in India.

Download Full-text

Dietary vitamin A supplementation improved reproductive performance by regulating ovarian expression of hormone receptors, caspase-3 and Fas in broiler breeders

Poultry Science ◽

10.3382/ps/pev305 ◽

2016 ◽

Vol 95 (1) ◽

pp. 30-40 ◽

Cited By ~ 10

Author(s):

Fang Chen ◽

Zongyong Jiang ◽

Shouqun Jiang ◽

Long Li ◽

Xiajing Lin ◽

...

Keyword(s):

Vitamin A ◽

Reproductive Performance ◽

Caspase 3 ◽

Hormone Receptors ◽

Dietary Vitamin ◽

Broiler Breeders ◽

Vitamin A Supplementation

Download Full-text

Effect of early weaning age on growth performance, nutrient digestibility, and serum parameters of lambs

Animal Production Science ◽

10.1071/an15079 ◽

2017 ◽

Vol 57 (1) ◽

pp. 110 ◽

Cited By ~ 3

Author(s):

J.-M. Chai ◽

T. Ma ◽

H.-C. Wang ◽

M.-L. Qi ◽

Y. Tu ◽

...

Keyword(s):

Organic Matter ◽

Growth Performance ◽

Dry Matter ◽

Nutrient Digestibility ◽

Apparent Digestibility ◽

Early Weaning ◽

Serum Parameters ◽

Creep Feed ◽

Nutrient Utilisation ◽

Weaning Age

To determine the effect of a weaning program on growth performance, nutrient digestibility, and serum parameters in Hu lambs, 48 newly born twin lambs (2.53 ± 0.13 kg; 24 male and 24 female) were randomly divided into four treatments: ewe reared (ER) or weaned at 10, 20, or 30 days post birth (EW10, EW20, and EW30) and fed milk replacer (MR). All liquid feed were eliminated at 60 days of age. Creep feed was offered ad libitum to all lambs from 15 to 90 days of age. The results indicated that lambs fed MR had higher liveweight, average daily gain, and creep feed intake (P < 0.001) than those in the ER group. There were no differences between treatments in the apparent digestibility of dry matter, organic matter, nitrogen or phosphorus (P > 0.05) from 50 to 60 days of age. The apparent digestibility of dry matter, organic matter, nitrogen and phosphorus of EW20 and EW30 groups were significantly higher (P < 0.05) than that of EW10 and ER groups from 80 to 90 days of age. Lambs in the EW10 group had higher concentration of albumin, serum urea nitrogen, and immunoglobulin G levels than those of other groups (P < 0.05). In conclusion, early weaning could improve creep intake, growth performance, and nutrient utilisation of Hu lambs. Early weaning age had a significant effect on the growth of lambs.

Download Full-text