Role Of Diet And Physical Activity In Patients With Coronary Artery Disease In South Asian Population: A Case Control Study

2008 ◽  
Vol 18 (9) ◽  
pp. 720-721
Author(s):  
SM Shah ◽  
S. Nishtar ◽  
A. Merchant
Keyword(s):  
Physical Activity ◽  
South Asian ◽  
Case Control Study ◽  
Asian Population ◽  
Case Control ◽  
South Asian Population ◽  
Diet And Physical Activity ◽  
Artery Disease ◽  
Control Study

Role of SNPs of CPTIA and CROT genes in the carnitine-shuttle in coronary artery disease: a case-control study

2019 ◽  
Vol 44 (6) ◽  
pp. 822-830
Author(s):  
Aslihan Demircan ◽  
Ender Coskunpinar ◽  
Deniz Kanca ◽  
Gulcin Ozkara ◽  
Fatih Yanar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acids ◽  
Case Control Study ◽  
Threshold Value ◽  
Case Control ◽  
Long Chain Fatty Acids ◽  
Artery Disease ◽  
Control Study ◽  
Long Chain

Abstract Objective Fatty acid β-oxidation defects can lead to difficulties at covering energy requirement of heart. The carnitine-shuttle is responsible for the transfering of long-chain fatty acids from the internal mitochondrial membrane. The role of genetic variants of the enzymes in the carnitine shuttle in coronary artery disease (CAD) has not been studied. Therefore, we performed a case-control study investigating the possible relation between the CPTIA-rs3019613 and CROT-rs2214930 gene variations located carnitine shuttle and CAD risk. Materials and methods Study groups were comprised of 96 CAD patients and 85 controls. CPTIA-rs3019613 G > A and CROT-rs2214930 T > C polymorphisms were determined by real-time-PCR. Results The CROT-rs2214930-CC genotype was found to be associated with decreased HDL-cholesterol (HDL-C) in controls (p = 0.029). In patients with CPTIA-rs3019613-A allele, body mass index (BMI) (p = 0.016) and BMI threshold-value (p = 0.030) were found be higher compared to those with GG-genotype, while HDL-C threshold-value (HDL-C ≤ 0.90 mmol/L) was found to be lower (p = 0.015). Regression analysis confirmed CPTIA-rs3019613-A allele has a significant relationship with decreased HDL-C (p = 0.009) in patients. Conclusion Our study indicated that the polymorphisms of the CROT and CPTIA genes related to β-oxidation of long-chain fatty acids had an important effect on serum HDL-C levels and may be a potential risk for CAD.

scholarly journals O8A.5 Total energy expenditure and risk of lymphoma subtypes: results from the european epilymph case-control study

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A71.2-A71
Author(s):  
Pierluigi Cocco
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Total Energy ◽  
Case Control Study ◽  
B Cell Lymphoma ◽  
Case Control ◽  
Total Energy Expenditure ◽  
Recreational Physical Activity ◽  
Control Study

IntroductionPhysical activity is known to convey protection against several cancers, but results on risk of lymphoma and its subtypes have been inconsistent. A possible reason might be confounding by workplace exposures associated with occupational energy expenditure, which was not considered in studies of recreational physical activity. It is also unclear whether energy expenditure acts directly, or through preventing obesity.ObjectivesTo investigate the role of energy expenditure, including occupational and recreational physical activity, on risk of lymphoma subtypes.Materials and methodsBased on questionnaire information on lifetime recreational physical activity and lifetime occupational history available for all participants to the multicenter EpiLymph case-control study, we estimated energy expenditure at work by occupational ISCO68 code, and we applied it to the work histories of study subjects. We also categorized hours of lifetime recreational physical activity into quartiles. We calculated risk of lymphoma subtypes with unconditional polytomous regression analysis, associated with increasing categories of lifetime energy expenditure at work (EEW), increasing categories of recreational physical activity (RPA), and their interaction term (total energy expenditure, TEE), adjusting by age, gender, education, body mass index (BMI), and history of farm work and solvents use.ResultsRisk of lymphoma overall, diffuse large B cell lymphoma and multiple myeloma was not associated with EEW, RPA and TEE. Risk of follicular lymphoma and chronic lymphocytic leukemia associated were elevated with medium and high EEW (OR 3.1, 95% CI 1.5–6.1; (OR 2.5 95% CI 1.2–5.1, respectively), but there was not a significant upward trend.ConclusionsFurther epidemiologic and mechanistic research is warranted to assess the role of physical activity in the etiology of lymphoma subtypes. New standardized energy expenditure assessment methods, as the ones herein developed, might contribute to a better understanding of the nature of the observed inconsistent findings.

1318 The role of physical activity on the development of acute coronary syndromes in diabetic patients. A case-control study

2008 ◽  
Vol 7 (1_suppl) ◽  
pp. 12-12
Author(s):  
Georgia Triantafillou ◽  
Theodora Mihalopoulou ◽  
Maria Salourou ◽  
Elisavet Antoniadi ◽  
Varvara Psaroudaki ◽  
...  
Keyword(s):  
Physical Activity ◽  
Acute Coronary Syndromes ◽  
Case Control Study ◽  
Case Control ◽  
Diabetic Patients ◽  
Coronary Syndromes ◽  
Control Study

Diet and Physical aActivity Intervention Effectiveness in Acute Mental Patients, During Hospitalization: A Matched Case-control Study

2017 ◽  
Vol 41 (S1) ◽  
pp. S137-S138
Author(s):  
J. Isaac ◽  
S. Guerreiro ◽  
C. Pinheiro ◽  
A. Pardal ◽  
N. Correia ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mental Illness ◽  
Case Control Study ◽  
Case Control ◽  
Activity Program ◽  
Diet And Physical Activity ◽  
Daily Dose ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

IntroductionDiet and physical activity interventions are effective in psychiatric outpatients that suffer from obesity, namely those treated with antipsychotic drugs. However, there is less evidence related to these interventions in hospitalised acute patients.AimTo evaluate the effect of a diet and physical activity program on weight and BMI variation in acute psychiatric patients during hospitalisation.MethodsMatched case-control study from January to September 2016. Inclusion criteria: patients with at least 15 days of hospitalisation in an acute psychiatry ward, evaluated by a nutritionist in the admission and medical discharge. The intervention consisted in a diet and physical activity program, with total restriction to visitors to bring food to the patients. Statistical analysis was done with T-student and multiple linear regression taking into account the effect of age, sex, daily dose of antipsychotics, and days of hospitalisation.ResultsSixty-six patients were studied (34 cases and 32 controls). Groups were statistically similar concerning the average of age, daily dose of antipsychotics, days of hospitalisation and sex. The differences of weight gain during hospitalisation were 0.088 kg (cases) versus 1484 kg (controls), P < 0.05. And the differences of the increased BMI during the hospitalisation were 0.041 kg/m2 (cases) versus 0.509 kg/m2 (controls), P < 0.05.ConclusionsObesity presents challenging health problems for individuals with severe mental illness that require inpatient treatment. This study provides evidence that individuals with acute mental illness can benefit from weight control interventions during their hospitalisation, in special a total restriction to visitors to bring food to the patients.

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