No impact of surgery on cognitive function: a longitudinal study of middle-aged Danish twins

2018 ◽  
Vol 28 (2) ◽  
pp. 95-101.e1 ◽  
Author(s):  
Unni Dokkedal ◽  
Mette Wod ◽  
Mikael Thinggaard ◽  
Tom Giedsing Hansen ◽  
Lars Simon Rasmussen ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Middle Aged

Validity of Self-Rated Memory Among Middle-Aged and Older Chinese Adults: Results From the China Health and Retirement Longitudinal Study (CHARLS)

Assessment ◽  
2017 ◽  
Vol 26 (8) ◽  
pp. 1582-1593 ◽  
Author(s):  
Zhiyong Huang ◽  
Jürgen Maurer
Keyword(s):  
Primary Care ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Test Performance ◽  
National Sample ◽  
Sociodemographic Factors ◽  
Memory Test ◽  
Care Practice ◽  
Middle Aged ◽  
Low Sensitivity

Memory self-ratings are often used in primary care practice and social surveys due to its relative ease of administration. Yet their usefulness to accurately measure individuals’ memory-related cognitive function is largely unknown. This article assesses the construct validity of self-rated memory for measuring memory-related cognitive function among middle-aged and older adults (45+ years) in China using a national sample ( N = 13,690) from the China Health and Retirement Longitudinal Study. We first compare self-rated memory with a number of well-established memory tests and then investigate the role of sociodemographic factors in determining self-reports conditional on memory test performance. We find that self-rated memory is only weakly correlated with memory test performance and yields low sensitivity and specificity in detecting individuals with relatively poor memory test performance. We also find evidence for substantial differential item functioning across sociodemographic groups. Our results, therefore, caution against the use of simple self-rated memory measures for memory assessments in primary care or survey research.

A change in social activity affect cognitive function in middle-aged and older Koreans: analysis of a Korean longitudinal study on aging (2006-2012)

2016 ◽  
Vol 31 (8) ◽  
pp. 912-919 ◽  
Author(s):  
Young Choi ◽  
Sohee Park ◽  
Kyoung Hee Cho ◽  
Sung-Youn Chun ◽  
Eun-Cheol Park
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Social Activity ◽  
Middle Aged

scholarly journals Association between anemia and cognitive decline among Chinese middle-aged and elderly: evidence from the China health and retirement longitudinal study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Tingting Qin ◽  
Mingming Yan ◽  
Zhen Fu ◽  
Yating Song ◽  
Wanrong Lu ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Episodic Memory ◽  
Cognitive Decline ◽  
Cognitive Functions ◽  
Hemoglobin Concentration ◽  
Cognitive Test ◽  
Middle Aged ◽  
Cross Sectional ◽  
Global Cognitive Function

Abstract Background Our objective was to characterize the relationship of anemia and hemoglobin concentrations with cross-sectional cognitive functions and changes in cognitive functions over 2 years in a large sample of Chinese middle aged and elderly. Methods Ten thousand nine hundred eighteen adults aged 45 years or older participating in the China Health and Retirement Longitudinal Study (CHARLS) were used for cross-sectional analyses and 9324 were used for longitudinal analysis. Cognitive functions were assessed by memory recall (episodic memory), mental status (TICS), and global cognitive function at baseline survey (Visit 1) and first follow-up survey (Visit 2). The lower the cognitive test score, the worse the cognitive function. Anemia was defined as hemoglobin concentrations lower than 13 g/dl for men and lower than 12 g/dl for women. Adjusted multivariate regression analyses were used to explore the relationships of different cognitive domains with anemia and hemoglobin concentration. Results Overall, the prevalence of anemia was 12.86% and the mean hemoglobin concentration was 14.37 ± 2.20 g/dl. After adjusting for socio-demographic and health-related covariates, the cross-sectional association between anemia and global cognitive function [β (95%CI) = − 0.49(− 0.69~ − 0.29)], episodic memory [β (95%CI) = − 0.14(− 0.23~ − 0.05)], and TICS [β (95%CI) = − 0.23(− 0.38~ − 0.08)] were significant and did not differ by gender. The hemoglobin concentration was also associated with global cognitive function among the whole sample (P < 0.05 for all). The longitudinal analyses showed global cognitive function and episodic memory were associated with anemia independent of covariates (P < 0.05 for all). Sensitivity analyses further provided significant results showing the association between anemia and cognition decline (P < 0.05). Conclusion There was a cross-sectional and longitudinal association between anemia and accelerated decline in cognitive functions in Chinese middle-aged and elderly. This suggests that anemia and low hemoglobin concentrations are independent risk factors of cognitive decline.

scholarly journals Cognitive decline associated with anticholinergics, benzodiazepines, and Z-drugs: findings from The Irish Longitudinal Study on Ageing (TILDA)

2020 ◽  
Author(s):  
Frank Moriarty ◽  
George M Savva ◽  
Carlota M Grossi ◽  
Kathleen Bennett ◽  
Chris Fox ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Medication Use ◽  
Community Dwelling ◽  
Word Recall ◽  
Middle Aged ◽  
Anticholinergic Medications ◽  
Pharmacy Claims ◽  
Burden Scale

Aim To estimate the association between patterns of anticholinergic, benzodiazepine, and Z-drug medication use and change in cognitive function in middle-aged and older adults. Method This prospective cohort study used data from the first three waves of The Irish Longitudinal Study on Ageing (TILDA), including community-dwelling adults aged ≥50 years followed for up to four years (n=7,027). Cognitive function was assessed using the Mini Mental State Examination, animal naming test, and word recall tests. Regular medication use was self-reported at baseline and follow-up interviews at two and four years. Pharmacy dispensing claims for a subset (n=2,905) allowed assessment of medication use between interviews and cumulative dosage. Medication use at consecutive waves of TILDA was analysed in relation to change in cognitive function between waves. Results Strongly anticholinergic medications (Anticholinergic Cognitive Burden scale 3), benzodiazepines, and Z-drugs were reported by 7.3%, 5.8% and 5.1% of participants respectively at any time during the study. Adjusting for potential confounders, new anticholinergic use between interviews was associated with change in recall score (-1.09, 95% confidence interval -1.64, -0.53) over 2 years compared to non-use, but not with MMSE (0.07; 95%CI -0.21, 0.34) or animal naming (-0.70; -1.43, 0.03). The pharmacy claims analysis was consistent with this finding. Other hypothesised associations were not supported. Discussion Except for new use of anticholinergic medications, no other findings supported a risk of cognitive decline over 2-year periods in this middle-aged and older cohort. Patients and prescribers should weigh this potential risk against potential benefits of commencing anticholinergic medications.

scholarly journals RECIPROCAL RELATIONSHIP BETWEEN COGNITION AND EDENTULISM AMONG MIDDLE-AGED AND OLDER ADULTS IN CHINA

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S350-S350
Author(s):  
Nan Lu ◽  
Bei Wu ◽  
Yaolin Pei
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Oral Health ◽  
Cognitive Function ◽  
Empirical Evidence ◽  
Tooth Loss ◽  
Reciprocal Relationship ◽  
Middle Aged ◽  
Cognitive Health

Abstract While empirical evidence shows that cognitive function affects oral health and vice versa, there is a lack of empirical evidence to test the reciprocal relationship between these two indicators. This study aimed to examine this relationship among middle-aged and older adults in China. Data were derived from the 2011 and 2015 waves of the China Health and Retirement Longitudinal study. A two-wave cross-lag analysis was adopted to test the hypothesized model. Cognitive function in 2011 was found to be a significant predictor of complete tooth loss in 2015. Furthermore, complete tooth loss in 2011 was found to be a significant predictor of cognitive cognition in 2015. This finding demonstrates the reciprocal relationship between cognitive function and oral health. This study highlights the importance of improving both cognitive health and oral health for middle-aged and older adults. Policy and intervention implications are discussed.

scholarly journals Association between depressive-symptom trajectories and cognitive function in the late middle-aged and older population: results of the Korean Longitudinal Study of Ageing

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Dong-Woo Choi ◽  
Kyu-Tae Han ◽  
Jooeun Jeon ◽  
Sung-In Jang ◽  
Seung Ju Kim ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Depressive Symptom ◽  
Cognitive Function ◽  
Middle Aged ◽  
Older Population ◽  
Symptom Trajectories

scholarly journals Associations of sensory impairment and cognitive function in middle-aged and older Chinese population: The China Health and Retirement Longitudinal Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Xiaohuan Zhao ◽  
Yifan Zhou ◽  
Kunchen Wei ◽  
Xinyue Bai ◽  
Jingfa Zhang ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Chinese Population ◽  
Sensory Impairment ◽  
Middle Aged ◽  
Older Chinese

scholarly journals Exploring the reciprocal relationship between cognitive function and edentulism among middle-aged and older adults in China

2020 ◽  
Author(s):  
Nan Lu ◽  
Bei Wu ◽  
Yaolin Pei
Keyword(s):  
Older Adults ◽  
Developing Countries ◽  
Longitudinal Study ◽  
Oral Health ◽  
Cognitive Function ◽  
Age Groups ◽  
Reciprocal Relationship ◽  
Middle Aged ◽  
Reciprocal Relationships

Abstract Objective Previous longitudinal studies have found that cognitive function affected oral health, and vice versa. However, research is lacking on the reciprocal relationships between cognitive function and edentulism simultaneously, especially in developing countries. The present study aimed to examine the reciprocal relationship between cognitive function and edentulism among middle-aged and older adults in China. Methods Data were derived from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study. The sample included 14,038 respondents aged 45 or older. A two-wave cross-lagged analysis was adopted to test the hypothesized model. Results Among respondents aged 45–59, baseline cognitive function was associated with subsequent edentulism [b = −0.017, standard deviation (SD) = 0.006, P &lt; 0.01]. In contrast, baseline edentulism was not significantly associated with poorer cognitive function at the follow-up wave (b = −0.744, SD = 0.383, P &gt; 0.05). However, among respondents aged 60 or older, baseline cognitive function was associated with subsequent edentulism (b = −0.017, SD = 0.005, P &lt; 0.01), and baseline edentulism was also associated with follow-up lower levels of cognitive function (b = −0.419, SD = 0.143, P &lt; 0.01). Conclusions These findings demonstrated the reciprocal relationships of cognitive function and edentulism. However, such relationships varied across age groups. This study demonstrates the importance of developing programs and services to promote both cognitive and oral health, especially for those in older age.

scholarly journals Social engagement and cognitive function among middle-aged and older adults: gender-specific findings from the Korean longitudinal study of aging (2008–2018)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sarah Soyeon Oh ◽  
Eunhee Cho ◽  
Bada Kang
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Social Engagement ◽  
Social Activity ◽  
Later Life ◽  
Estimating Equation ◽  
Senior Center ◽  
Middle Aged ◽  
Gender Specific

AbstractRecent findings suggest that social disengagement in later life may result in cognitive decline and increase risk of Alzheimer’s and related dementias. However, little is known regarding the gender-specific longitudinal association between social engagement and cognition among middle-aged and older adults. Using data from a nationally representative sample of 2707 men and 5196 women from the Korean longitudinal study of aging, we examined the gender-specific association between social activity and cognitive function. Results from the generalized estimating equation model showed that compared to individuals with consistent social engagement (religious, senior center, sport, reunion, voluntary, political), individuals with inconsistent engagement had lower cognitive function. Transitioning from engagement to non-engagement was associated with lower cognitive function among men only. Not being part of a senior center was associated with decreased cognitive function among both genders, while not being part of a religious group was significant for women only. While marital status was a significant predictor of cognitive ability for women, depression was a significant predictor for men. These findings have implications for policy-makers as interventions targeting improved cognitive function among middle-aged and older adults may be more effective when gender-specific predictors are taken into consideration.

scholarly journals Intergenerational Ties in Context: Association between Caring for Grandchildren and Cognitive Function in Middle-Aged and Older Chinese

2020 ◽  
Vol 18 (1) ◽  
pp. 21
Author(s):  
Shiming Liao ◽  
Ling Qi ◽  
Jie Xiong ◽  
Jie Yan ◽  
Ruoxi Wang
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Cultural Context ◽  
Gender Disparity ◽  
Three Dimensions ◽  
Moderate Intensity ◽  
Middle Aged ◽  
Assessment Protocol ◽  
Older Chinese ◽  
The Relationship

Grandchild caregiving is suggested to improve the elderly’s cognitive function, but the specific relationship remains under-investigated. Considering gender disparity, this study aimed to understand the relationship between grandchild caregiving and cognition. In total, 7236 Chinese residents (≥45 years old) were selected from the 2015 China Health and Retirement Longitudinal Study (CHARLS). The China Health and Retirement Longitudinal Study Harmonized Cognitive Assessment Protocol (CHARLS-HCAP) was used to measure cognition. Grandparenting was measured from three dimensions: caregiving frequency, intensity, and the number of grandchildren cared for. The relationship was examined by multivariate linear regression, with age as a moderator. The results showed that the majority of respondents provided care to their grandchildren, especially grandmothers. Grandchild caregiving was positively associated with cognition (β = 0.686, 95% CI = 0.334–1.038), especially in the older-aged group. Moderate, not regular grandparenting, or caring for one grandchild was more positively associated with cognitive function. However, intensive and regular grandchild care was significantly associated with cognition only in men. No moderating effects of age were found in women. The study confirmed that moderate intensity and frequency of caregiving was related to better cognitive function in middle-aged and older Chinese population, whereas cultural context and gender differences could be considered when designing targeted policies.

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