Novel Support Surface To Alleviate Pressure Ulcer Formation During The Rehabilitation Of Immobile Patients: A Preliminary Investigation

2021 ◽  
Vol 102 (10) ◽  
pp. e39-e40
Author(s):  
Wen Li Lui ◽  
Matthew Rong Jie Tay ◽  
Dan Wang ◽  
Keng Hwee Chiam ◽  
Shirlene Toh ◽  
...  
Author(s):  
Wei Carrigan ◽  
Pavan Nuthi ◽  
Charu Pande ◽  
Caleb P. Nothnagle ◽  
Muthu B. J. Wijesundara

Pressure ulcers are a serious reoccurring complication among wheelchair users with impaired mobility and sensation. It is postulated that external mechanical loading, specifically on bony prominences, is a major contributing factor in pressure ulcer formation. Prevention strategies mainly center on reducing the magnitude and duration of external forces acting upon the body. Seat cushion technologies for reducing pressure ulcer prevalence often employ soft materials and customized cushion geometries. Air cell arrays used in time-based pressure modulation techniques are seen as a promising alternative; however, this approach could be further enhanced by adding real-time pressure profile mapping to enable automated pressure modulation customizable for each user’s condition. The work presented here describes the development of a prototype support surface and pressure modulation algorithm which can monitor interface pressure as well as automatically offload and redistribute concentrated pressure. This prototype is comprised of arrays of sensorized polymeric soft air cell actuators which are modulated by a pneumatic controller. Each actuator’s pressure can be changed independently which results in a change to the interface pressure allowing us to offload targeted regions and provide local adjustment for redistribution. The pressure mapping, redistribution, and offloading capabilities of the prototype are demonstrated using pressure modulation algorithms described here.


2001 ◽  
Vol 281 (1) ◽  
pp. H67-H74 ◽  
Author(s):  
Shayn M. Peirce ◽  
Thomas C. Skalak ◽  
Jayson M. Rieger ◽  
Timothy L. Macdonald ◽  
Joel Linden

Activation of A2A adenosine receptors (A2A-AR) by ATL-146e (formerly DWH-146e) prevents inflammatory cell activation and adhesion. Recurrent ischemia-reperfusion (I/R) of the skin results in pressure ulcer formation, a major clinical problem. ATL-146e was evaluated in a novel reproducible rat model of pressure ulcer. A 9-cm2 region of dorsal rat skin was cyclically compressed at 50 mmHg using a surgically implanted metal plate and an overlying magnet to generate reproducible tissue necrosis. Osmotic minipumps were implanted into 24 rats divided into four equal groups to infuse vehicle (control), ATL-146e (0.004 μg · kg−1 · min−1), ATL-146e plus an equimolar concentration of A2A antagonist, ZM-241385, or ZM-241385 alone. Each group received 10 I/R cycles. In non-I/R-treated skin, ATL-146e has no effect on blood flow. I/R-treated skin of the ATL-146e group compared with the vehicle group had 65% less necrotic area, 31% less inhibition of average skin blood flow, and fewer extravasated leukocytes (23 ± 3 vs. 49 ± 6 per 500 μm2). These data suggest that ATL-146e, acting via an A2A-AR, reduces leukocyte infiltration and is a potent prophylactic for I/R injury in skin.


2000 ◽  
Vol 120 (8-9) ◽  
pp. 1092-1097
Author(s):  
Seiichi Suzuki ◽  
Fukuko Ohnuma ◽  
Chikako Yanami ◽  
Tomoko Murayama ◽  
Makoto Akiyoshi

2011 ◽  
Vol 131 (11) ◽  
pp. 2316-2322 ◽  
Author(s):  
Claire Demiot ◽  
Vincent Sarrazy ◽  
James Javellaud ◽  
Loriane Gourloi ◽  
Laurent Botelle ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sahori Yamazaki ◽  
Akiko Sekiguchi ◽  
Akihiko Uchiyama ◽  
Chisako Fujiwara ◽  
Yuta Inoue ◽  
...  

2010 ◽  
Vol 13 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Tsokuang Wu ◽  
Shin-Tien Wang ◽  
Pi-Chu Lin ◽  
Chien-Lin Liu ◽  
Yann-Fen C. Chao

The purpose of this study was to evaluate the effect of high-density foam (HDF) pads versus viscoelastic polymer (VP) pads in the prevention of pressure ulcer formation during spinal surgery and their cost-effectiveness. Subjects were 30 patients who underwent spinal surgery for more than 3 hr in a prone position. One side of the chest and iliac crest was padded with HDF pads and the other side was padded with VP pads. An Xsensor® pressure measuring sheet was placed between the pad and the patient. Bilateral chest and iliac crest points were observed for the presence of pressure ulcers at 30 min after the operation. Results showed that a pressure ulcer had occurred at 9 of 120 compression points (7.5% of the total), 30 min after the operation. Risk evaluation showed that female gender, weight <50 kg, and body mass index (BMI) <18 kg/m2 as well as location (the iliac crest) were all risk factors for development of pressure ulcers. The most significant factor was BMI <18 kg/m2. The average and peak pressures measured at the points padded with the VP pads were significantly lower than those padded with the HDF pads. However, there was no significant difference between the VP and the HDF pads regarding ulcer prevention. Because the cost of a VP pad is 250 times greater than that of an HDF pad of similar size, the VP pad should only be considered for use in high-risk patients.


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