scholarly journals Ultrasound assisted extraction of bioactive compounds from Nephelium lappaceum L. fruit peel using central composite face centered response surface design

2017 ◽  
Vol 10 ◽  
pp. S1145-S1157 ◽  
Author(s):  
J. Prakash Maran ◽  
S. Manikandan ◽  
C. Vigna Nivetha ◽  
R. Dinesh
Keyword(s):  
Response Surface Design ◽  
Ultrasound Assisted Extraction ◽  
Fruit Peel ◽  
Surface Design ◽  
Assisted Extraction ◽  
Nephelium Lappaceum ◽  
Ultrasound Assisted ◽  
Face Centered ◽  
Composite Face ◽  
Central Composite

scholarly journals Ultrasound-Assisted Extraction of Total Acetogenins from the Soursop Fruit by Response Surface Methodology

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1139 ◽  
Author(s):  
Gabriela Aguilar-Hernández ◽  
María de los Ángeles Vivar-Vera ◽  
María de Lourdes García-Magaña ◽  
Napoleón González-Silva ◽  
Alejandro Pérez-Larios ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Large Scale ◽  
Raw Material ◽  
Ultrasound Assisted Extraction ◽  
Fruit Peel ◽  
Optimal Method ◽  
Assisted Extraction ◽  
Ultrasound Assisted ◽  
By Products

The soursop fruit or Annona muricata (A. muricata) fruit is recognized by its bioactive compounds and acetogenins (ACG) are among the most important. The effect of ACGs, with greater importance in health, is that they present anti-tumor activity; however, the methods of extraction of ACGs are very slow and with a high expenditure of solvents. To our knowledge, there is no report of an optimal method for the extraction of acetogenins from the Annonaceae family by ultrasound-assisted extraction (UAE); therefore, the aim was to find the best UEA conditions of acetogenins from A. muricata fruit (peel, pulp, seed, and columella) by using response surface methodology. The effect of amplitude (40%, 70%, and 100%), time (5, 10, and 15 min), and pulse-cycle (0.4, 0.7, and 1 s) of ultrasound at 24 kHz was evaluated on the total acetogenin content (TAC). Optimal extraction conditions of acetogenins (ACGs) with UEA were compared with the extraction of ACGs by maceration. The optimal UEA conditions in the A. muricata pulp and by-products were dependent on each raw material. The highest TAC was found in the seed (13.01 mg/g dry weight (DW)), followed by the peel (1.69 mg/g DW), the pulp (1.67 mg/g DW), and columella (1.52 mg/g DW). The experimental TAC correlated well with the model (Adjusted R2 with values between 0.88 and 0.97). The highest effectiveness in ACG extraction was obtained in seeds and peels using UEA compared to extraction by maceration (993% and 650%, respectively). The results showed that A. muricata by-products are an important source of ACGs and that UAE could be a viable alternative, with high potential for large-scale extraction.

scholarly journals Ultrasound-assisted extraction of antioxidant polyphenolic compounds from Nephelium lappaceum L. (Mexican variety) husk

2018 ◽  
Vol 11 (12) ◽  
pp. 676 ◽  
Author(s):  
Juan Ascacio-Valdés ◽  
Adriana Mendez-Flores ◽  
Ayerim Hérnandez-Almanza ◽  
Aidé Sáenz-Galindo ◽  
Jesús Morlett-Chávez ◽  
...  
Keyword(s):  
Polyphenolic Compounds ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Nephelium Lappaceum ◽  
Ultrasound Assisted

scholarly journals Ultrasound-Assisted Phytochemical Extraction Condition Optimization Using Response Surface Methodology from Perlette Grapes (Vitis vinifera)

Processes ◽  
2019 ◽  
Vol 7 (10) ◽  
pp. 749 ◽  
Author(s):  
Muhammad Kaleem ◽  
Asif Ahmad ◽  
Rai Muhammad Amir ◽  
Ghazala Kaukab Raja
Keyword(s):  
Antioxidant Activity ◽  
Response Surface Methodology ◽  
Acetic Acid ◽  
Vitis Vinifera ◽  
Central Composite Design ◽  
Flavonoid Content ◽  
Ultrasound Assisted Extraction ◽  
Assisted Extraction ◽  
Ultrasound Assisted ◽  
Central Composite

In the current study, bioactive compounds of Vitis vinifera (Perlette) were extracted using an ultrasound-assisted extraction technique. The central composite design of response surface methodology (RSM) was used to determine the effect of time, temperature, and concentration of acetic acid on response variables that include extract yield, total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity of Vitis vinifera extracts. The results of the central composite design of RSM revealed that the quadratic polynomial model is best fitted to experimental results, with all the responses having a regression coefficient greater than 0.9. Optimized extraction levels include 26.5 min, an extraction temperature of 59 °C, and an acetic acid concentration of 62.9% with good extraction yield results of 34.95 g/100 g dry weight (DW) of grapes, TPC 34.38 mg gallic acid equivalent per gram (GAE/g) DW, flavonoid content 10.21 mg quercetin equivalents per gram (QEQ/g) DW, and antioxidant activity of 9.11 mg/100 mL ascorbic acid equivalent. The present study showed that acetic acid can be effectively used for the ultrasound-assisted extraction of polyphenols, flavonoids, and antioxidants of Vitis vinifera. These optimized conditions can be used for the extraction of bioactive compounds that can be for the development of nutraceutical products.

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