Ultrasound-assisted extraction of antioxidant polyphenolic compounds from Nephelium lappaceum L. (Mexican variety) husk

Polyphenolic compounds, plant secondary metabolites essential for plant survival, are known for their high antioxidant and anti-inflammatory activity. In addition, several polyphenols, such as phloretin, also have potential antiviral effects, making these compounds potential ingredients of biofunctional foods. A promising source for the extraction of phloretin is a by-product of apple production—apple tree leaves. Focusing on green technologies, the first aim of the present study was to optimize the direct ultrasound-assisted extraction conditions to gain the maximum yield of phloretin from air-dried apple leaves. For the optimization of process parameters, we applied the response surface method with Box–Behnken design. The optimal extraction conditions were extraction time 14.4 min, sonication amplitude 10% and 10 g of sample per 100 mL solvent (70% ethanol, w/w). Using these conditions, we assessed the content of individual and total polyphenolic compounds along with antioxidant activity in the leaves of different autumn and winter apple cultivars grown in Estonia. The analyses were carried out with chromatographic (HPLC-DAD-MS/MS) and spectrophotometric methods. The phloretin concentration ranged from 292 to 726 µg/g and antioxidant activity from 6.06 to 11.42 mg GA eq./g, these being the highest in the local winter cultivars ‘Paide taliõun’ and ‘Tellissaare’, respectively.

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Ultrasound-assisted extraction of polysaccharide from Nephelium lappaceum L. fruit peel

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2014.07.032 ◽

2014 ◽

Vol 70 ◽

pp. 530-536 ◽

Cited By ~ 64

Author(s):

J. Prakash Maran ◽

B. Priya

Keyword(s):

Ultrasound Assisted Extraction ◽

Fruit Peel ◽

Assisted Extraction ◽

Nephelium Lappaceum ◽

Ultrasound Assisted

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Modeling and optimization of ultrasound-assisted extraction of polyphenolic compounds from Aronia melanocarpa by-products from filter-tea factory

Ultrasonics Sonochemistry ◽

10.1016/j.ultsonch.2014.10.002 ◽

2015 ◽

Vol 23 ◽

pp. 360-368 ◽

Cited By ~ 82

Author(s):

Milica Ramić ◽

Senka Vidović ◽

Zoran Zeković ◽

Jelena Vladić ◽

Aleksandra Cvejin ◽

...

Keyword(s):

Polyphenolic Compounds ◽

Ultrasound Assisted Extraction ◽

Modeling And Optimization ◽

Aronia Melanocarpa ◽

Assisted Extraction ◽

Ultrasound Assisted ◽

By Products

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Optimization of ultrasound-assisted extraction of polyphenolic compounds from pomegranate peel using response surface methodology

Separation and Purification Technology ◽

10.1016/j.seppur.2017.11.032 ◽

2018 ◽

Vol 194 ◽

pp. 40-47 ◽

Cited By ~ 54

Author(s):

Jelena Živković ◽

Katarina Šavikin ◽

Teodora Janković ◽

Nada Ćujić ◽

Nebojša Menković

Keyword(s):

Response Surface Methodology ◽

Response Surface ◽

Polyphenolic Compounds ◽

Ultrasound Assisted Extraction ◽

Pomegranate Peel ◽

Assisted Extraction ◽

Ultrasound Assisted

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Ultrasound assisted extraction of bioactive compounds from Nephelium lappaceum L. fruit peel using central composite face centered response surface design

Arabian Journal of Chemistry ◽

10.1016/j.arabjc.2013.02.007 ◽

2017 ◽

Vol 10 ◽

pp. S1145-S1157 ◽

Cited By ~ 87

Author(s):

J. Prakash Maran ◽

S. Manikandan ◽

C. Vigna Nivetha ◽

R. Dinesh

Keyword(s):

Response Surface Design ◽

Ultrasound Assisted Extraction ◽

Fruit Peel ◽

Surface Design ◽

Assisted Extraction ◽

Nephelium Lappaceum ◽

Ultrasound Assisted ◽

Face Centered ◽

Composite Face ◽

Central Composite

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Hard Cap Espresso Machine Extraction of Polyphenolic Compounds from Pulses

Journal of the Mexican Chemical Society ◽

10.29356/jmcs.v62i2.371 ◽

2018 ◽

Vol 62 (2) ◽

Author(s):

Amira Melki ◽

Yassine Mokaddem ◽

Francesc A Esteve-Turrillas ◽

Miguel De la Guardia

Keyword(s):

Limit Of Detection ◽

Extraction Procedure ◽

Food Samples ◽

Polyphenolic Compounds ◽

Ultrasound Assisted Extraction ◽

Dispersing Agent ◽

Assisted Extraction ◽

Ultrasound Assisted ◽

Polyphenol Extraction ◽

Domestic Machine

A hard cap espresso machine was employed for the extraction of polyphenolic compounds from food samples as dry legumes and pulses. 100 mg of ground dry sample was mixed with a dispersing agent and placed in a refillable stainless steel capsule with a borosilicate filter. A complete polyphenol extraction was achieved by using 150 mL ethanol 50 % (v/v) in water and determined by Folin-Ciocalteu spectrophotometric method. The method provided a limit of detection of 0.4 mg g-1. The whole extraction procedure was achieved in less than one minute using the mild extraction conditions of 72°C and 19 bars given by the domestic machine. Fifteen varieties of food samples (3 lentils, 6 beans, 5 chickpeas, and 1 sorghum) were purchased in Spanish and Tunisian markets and analyzed by the proposed procedure. Obtained results were compared with those found by a reference extraction method based on ultrasound-assisted extraction, being statistically comparable. The content of polyphenolic compounds in the analyzed commercial samples varied from 4.6 to 5.5 mg g-1 for lentils, from 3.4 to 5.8 mg g-1 for beans, from 2.2 to 3.5 mg g-1 for chickpeas, and 3.0 mg g-1 for sorghum.

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Ultrasound assisted extraction of polyphenolic compounds from red sorghum ( Sorghum bicolor L.) bran and their biological activities and polyphenolic compositions

Industrial Crops and Products ◽

10.1016/j.indcrop.2017.12.019 ◽

2018 ◽

Vol 112 ◽

pp. 296-304 ◽

Cited By ~ 36

Author(s):

Xiaoping Luo ◽

Jiemei Cui ◽

Haihui Zhang ◽

Yuqing Duan ◽

Di Zhang ◽

...

Keyword(s):

Sorghum Bicolor ◽

Biological Activities ◽

Polyphenolic Compounds ◽

Ultrasound Assisted Extraction ◽

Assisted Extraction ◽

Ultrasound Assisted ◽

Sorghum Bicolor L

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Innovative Extraction Techniques for the Optimum Extraction of Phenolic Compounds from Peanut Meal and Evaluation of Their Biological Activities

Advances in Nutrition & Food Science ◽

10.33140/anfs.04.02.2 ◽

2019 ◽

Vol 4 (2) ◽

Keyword(s):

Phenolic Compounds ◽

Carcinoma Cell ◽

Biological Activities ◽

Peanut Meal ◽

Ultrasound Assisted Extraction ◽

Carcinoma Cell Lines ◽

Assisted Extraction ◽

Phenolic Extract ◽

Ultrasound Assisted ◽

Water Ratio

There is a worldwide demand for phenolic compounds (PC) because they exhibit several biological activities. This work aimed at extracting phenolic compounds from peanut meal. The methods of extraction were mainly: conventional solvent extraction (traditional methods) and ultrasound assisted extraction (recent methods) and comparing their results. Peanut meal (PM) was prepared by defatting with n-hexane, and then extracted by the two previous methods. First, the conventional solvents used were 80% methanol, ethanol, acetone, isopropanol, and distilled water. Then studied Different parameters such as meal: water ratio, also the effect of temperature and the pH on the extraction process. Second, ultrasonic assisted extractions (USAE), the parameters investigated were temperature, time and speed of sonication. Finally, all the extracts were analyzed by HPLC for their phenolic contents. Results indicated that the highest extracted PC achieved by solvents was in distilled water where 1:100, Meal: Water ratio which extracted 40 mg PC / g PM at 30& 35°C. Highest extracted PC was achieved by alkaline medium at pH 12 more than acidic and neutral medium. While (USAE) at speed 8 ultrasonication and temperature 30ᵒC, extracted 49.2mg PC /g PM. Sothe ultrasound assisted extraction exhibited great influence on the extraction of phenolic compounds from peanut meal. The ultrasonic peanut extract was examined for its antioxidant, antimicrobial and anticarcinogenic activities. The antioxidant activity of PM phenolic extract prepared by ultrasonic technique, was measured by, β-carotene, and DPPH methods, and reducing antioxidant power. Results revealed values: 84.57, 57.72 and 5960 respectively. The PM extract showed different levels of antimicrobial activity against the pathogenic bacteria used. As for the anticarcinogenic effect PM phenolic extract most effective on inhibiting colon carcinoma and lung carcinoma cell lines with IC50 = 20.7 and 20.8 µ/ml., respectively. This was followed by intestinal carcinoma and liver carcinoma cell lines with IC50= 39.6 and 40.2µ/ml.

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