RNA-binding properties and RNA chaperone activity of human peroxiredoxin 1

2012 ◽  
Vol 425 (4) ◽  
pp. 730-734 ◽  
Author(s):  
Ji-Hee Kim ◽  
Jeong-Mi Lee ◽  
Hae Na Lee ◽  
Eun-Kyung Kim ◽  
Bin Ha ◽  
...  
Keyword(s):  
Rna Binding ◽  
Chaperone Activity ◽  
Binding Properties ◽  
Rna Chaperone ◽  
Peroxiredoxin 1

scholarly journals RNA chaperone activity and RNA-binding properties of the E. coli protein StpA

2007 ◽  
Vol 35 (4) ◽  
pp. 1257-1269 ◽  
Author(s):  
O. Mayer ◽  
L. Rajkowitsch ◽  
C. Lorenz ◽  
R. Konrat ◽  
R. Schroeder
Keyword(s):  
Rna Binding ◽  
Chaperone Activity ◽  
Binding Properties ◽  
Rna Chaperone ◽  
E Coli

scholarly journals Coronavirus Nucleocapsid Protein Facilitates Template Switching and Is Required for Efficient Transcription

2009 ◽  
Vol 84 (4) ◽  
pp. 2169-2175 ◽  
Author(s):  
Sonia Zúñiga ◽  
Jazmina L. G. Cruz ◽  
Isabel Sola ◽  
Pedro A. Mateos-Gómez ◽  
Lorena Palacio ◽  
...  
Keyword(s):  
Nucleocapsid Protein ◽  
Rna Binding ◽  
Chaperone Activity ◽  
Protein Domain ◽  
Transmissible Gastroenteritis Virus ◽  
Deletion Mutants ◽  
Template Switching ◽  
Rna Chaperone ◽  
N Protein

ABSTRACT Purified nucleocapsid protein (N protein) from transmissible gastroenteritis virus (TGEV) enhanced hammerhead ribozyme self-cleavage and favored nucleic acid annealing, properties that define RNA chaperones, as previously reported. Several TGEV N-protein deletion mutants were expressed in Escherichia coli and purified, and their RNA binding ability and RNA chaperone activity were evaluated. The smallest N-protein domain analyzed with RNA chaperone activity, facilitating DNA and RNA annealing, contained the central unstructured region (amino acids 117 to 268). Interestingly, N protein and its deletion mutants with RNA chaperone activity enhanced template switching in a retrovirus-derived heterologous system, reinforcing the concept that TGEV N protein is an RNA chaperone that could be involved in template switching. This result is in agreement with the observation that in vivo, N protein is not necessary for TGEV replication, but it is required for efficient transcription.

scholarly journals RNA binding property and RNA chaperone activity of dengue virus core protein and other viral RNA-interacting proteins

FEBS Letters ◽  
2011 ◽  
Vol 585 (16) ◽  
pp. 2575-2581 ◽  
Author(s):  
Wen-Li Pong ◽  
Zhi-Shun Huang ◽  
Pak-Guan Teoh ◽  
Chung-Chun Wang ◽  
Huey-Nan Wu
Keyword(s):  
Dengue Virus ◽  
Rna Binding ◽  
Core Protein ◽  
Chaperone Activity ◽  
Viral Rna ◽  
Binding Property ◽  
Interacting Proteins ◽  
Rna Chaperone ◽  
Virus Core
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