Covalent inhibition of P. falciparum ferredoxin-NADP+ reductase: Exploring alternative strategies for the development of new antimalarial drugs

2021 ◽  
Vol 577 ◽  
pp. 89-94
Author(s):  
Matteo de Rosa ◽  
Simona Nonnis ◽  
Alessandro Aliverti
Author(s):  
Peter Khooshabeh ◽  
Mary Hegarty ◽  
Thomas F. Shipley

Two experiments tested the hypothesis that imagery ability and figural complexity interact to affect the choice of mental rotation strategies. Participants performed the Shepard and Metzler (1971) mental rotation task. On half of the trials, the 3-D figures were manipulated to create “fragmented” figures, with some cubes missing. Good imagers were less accurate and had longer response times on fragmented figures than on complete figures. Poor imagers performed similarly on fragmented and complete figures. These results suggest that good imagers use holistic mental rotation strategies by default, but switch to alternative strategies depending on task demands, whereas poor imagers are less flexible and use piecemeal strategies regardless of the task demands.


2018 ◽  
Vol 3 (2) ◽  
Author(s):  
H.L Ahmad Murdani

Ketak handicraft is one of any other superior handicraft in Lombok Tengah Regency, as one of any other revenue generator for Lombok Tengah regency and to increase the prosperity of people in this industry, it is needed to find out the ways and strategies to improve the performance of this business. This research was categorized as a descriptive research which used case method approach, it was aimed to find out the position of ketak handicraft among handicraft industry in Lombok Tengah based on recent performance and to identify alternative strategies which can be chosen in order to improve the performance of this industry. In order to find out the position of ketak handicraft business, it was used BCG Agam analysis and based on this position the strategy for improving this business was selected based on this analysis, the position of third business was in the stars position, where alternative strategies that can be chosen were: (a) development of the existing product (market expansion for the existing product); (b) diversification; (c) horizontal merger. Suggestion recommended was to apply one of these strategies based on analysis that had been conducted.


2019 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Willy Tambunan ◽  
Theresia Amelia ◽  
Faris Prasetyohadi Priyana

Marketing is an essential aspect of the strategy of increasing product sales. Manis Bakery UMKM itself does not have a specific plan for promoting mani bread. This study aims to design the marketing strategy of UMKM Manis Bakery based on the concept of Quantitative Strategic Planning Matrix (QSPM), Competitive Profile Matrix (CPM), and Strategic Position and Action Evaluation (SPACE). This research conducted at Manis Bakery UMKM with respondents chosen were business owners and respondents who bought bread at least once a week or more. Based on the results of the analysis that has done, the results obtained that the strength possessed by the Sweet Bakery UMKM are products without preservatives, bread has a soft texture, food that is not easy to expire, strategic company location and affordable prices. The strategy is a priority based on six alternative strategies, namely creating sweet bread with flavors or innovations and making unique and attractive packaging that will do when having additional business capital.


2009 ◽  
Vol 7 ◽  
pp. 7-14
Author(s):  
Dhyanendra Bahadur Rai

The present paper is an attempt to portray the livelihood patterns of two marginalized communities such as Majhi and Kumal of Kumaltar village in the Arun valley, eastern Nepal. Data were collected from all 28 households of both communities. The findings show that agriculture and livestock now are the main occupations for their living. Prior to these, ferrying, fishing and pottering were their traditional occupations when they moved to Kumaltar in several years ago. As the production from agriculture and livestock is inadequate, other activities such as mobile trading of merchandise goods and local goods, pig and poultry farming, bamboo and ropes making, and local grains based country alcohol making have been adopted by them as alternative strategies for sustaining their livelihood. In addition, recently, the youths of these communities have migrated to different parts within the country, as well as in foreign countries for employment for better living in the village.The Geographical Journal of Nepal, Vol. 7, 2009: 7-14


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