Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds

Biomaterials ◽  
2004 ◽  
Vol 25 (16) ◽  
pp. 3211-3222 ◽  
Author(s):  
Hani A. Awad ◽  
M. Quinn Wickham ◽  
Holly A. Leddy ◽  
Jeffrey M. Gimble ◽  
Farshid Guilak
2011 ◽  
Vol 19 ◽  
pp. S43-S44
Author(s):  
C. O'Flatharta ◽  
E. Mooney ◽  
G. Shaw ◽  
B. Ranera ◽  
G. McKenna ◽  
...  

2007 ◽  
Vol 31 (9) ◽  
pp. 1042-1048 ◽  
Author(s):  
Sang Gyung Kim ◽  
Chang Ho Jeon ◽  
Hun suk Suh ◽  
Jung-Yoon Choe ◽  
Im-Hee Shin

2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Hajar Shafaei ◽  
Abolghasem Esmaeili ◽  
Mohammad Mardani ◽  
Shahnaz Razavi ◽  
Batol Hashenibeni ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Nicola Giuliani ◽  
Gina Lisignoli ◽  
Marina Magnani ◽  
Costantina Racano ◽  
Marina Bolzoni ◽  
...  

Human mesenchymal stem cells (hMSCs) are pluripotent adult stem cells capable of being differentiated into osteoblasts, adipocytes, and chondrocytes. The osteogenic differentiation of hMSCs is regulated either by systemic hormones or by local growth factors able to induce specific intracellular signal pathways that modify the expression and activity of several transcription factors. Runt-related transcription factor 2 (Runx2) and Wnt signaling-related molecules are the major factors critically involved in the osteogenic differentiation process by hMSCs, and SRY-related high-mobility-group (HMG) box transcription factor 9 (SOX9) is involved in the chondrogenic one. hMSCs have generated a great interest in the field of regenerative medicine, particularly in bone regeneration. In this paper, we focused our attention on the molecular mechanisms involved in osteogenic and chondrogenic differentiation of hMSC, and the potential clinical use of hMSCs in osteoarticular pediatric disease characterized by fracture nonunion and pseudarthrosis.


2005 ◽  
Vol 53 (S 3) ◽  
Author(s):  
W Röll ◽  
T Hashemi ◽  
M Breitbach ◽  
O Dewald ◽  
A Welz ◽  
...  

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