scholarly journals Analysis of Skeletal Muscle Gene Expression Patterns and the Impact of Functional Capacity in Patients With Systolic Heart Failure

2014 ◽  
Vol 20 (6) ◽  
pp. 422-430 ◽  
Author(s):  
Daniel E. Forman ◽  
Karla M. Daniels ◽  
Lawrence P. Cahalin ◽  
Alexandra Zavin ◽  
Kelly Allsup ◽  
...  
Keyword(s):  
Gene Expression ◽  
Heart Failure ◽  
Skeletal Muscle ◽  
Functional Capacity ◽  
Expression Patterns ◽  
Systolic Heart Failure ◽  
Gene Expression Patterns ◽  
Muscle Gene Expression ◽  
Muscle Gene ◽  
The Impact

scholarly journals CORRELATIONS BETWEEN RECOVERY KINETICS AND SKELETAL MUSCLE GENE EXPRESSION IN SYSTOLIC HEART FAILURE

2012 ◽  
Vol 59 (13) ◽  
pp. E937
Author(s):  
Jacob Joseph ◽  
Alexandra Zavin ◽  
Stewart H. Lecker ◽  
Karla Daniels ◽  
Kelly Allsup ◽  
...  
Keyword(s):  
Gene Expression ◽  
Heart Failure ◽  
Skeletal Muscle ◽  
Systolic Heart Failure ◽  
Muscle Gene Expression ◽  
Muscle Gene

scholarly journals Muscle Gene Expression Patterns in Human Rotator Cuff Pathology

2014 ◽  
Vol 96 (18) ◽  
pp. 1558-1565 ◽  
Author(s):  
Alexander Choo ◽  
Meagan McCarthy ◽  
Rajeswari Pichika ◽  
Eugene J Sato ◽  
Richard L Lieber ◽  
...  
Keyword(s):  
Gene Expression ◽  
Rotator Cuff ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Muscle Gene Expression ◽  
Muscle Gene ◽  
Human Rotator Cuff

scholarly journals Impact of hot and cold exposure on human skeletal muscle gene expression

2017 ◽  
Vol 42 (3) ◽  
pp. 319-325 ◽  
Author(s):  
Roksana B. Zak ◽  
Robert J. Shute ◽  
Matthew W.S. Heesch ◽  
D. Taylor La Salle ◽  
Matthew P. Bubak ◽  
...  
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
Mitochondrial Biogenesis ◽  
Room Temperature ◽  
Environmental Temperature ◽  
Human Model ◽  
Whole Body ◽  
Muscle Gene Expression ◽  
Muscle Gene ◽  
The Impact

Many human diseases lead to a loss of skeletal muscle metabolic function and mass. Local and environmental temperature can modulate the exercise-stimulated response of several genes involved in mitochondrial biogenesis and skeletal muscle function in a human model. However, the impact of environmental temperature, independent of exercise, has not been addressed in a human model. Thus, the purpose of this study was to compare the effects of exposure to hot, cold, and room temperature conditions on skeletal muscle gene expression related to mitochondrial biogenesis and muscle mass. Recreationally trained male subjects (n = 12) had muscle biopsies taken from the vastus lateralis before and after 3 h of exposure to hot (33 °C), cold (7 °C), or room temperature (20 °C) conditions. Temperature had no effect on most of the genes related to mitochondrial biogenesis, myogenesis, or proteolysis (p > 0.05). Core temperature was significantly higher in hot and cold environments compared with room temperature (37.2 ± 0.1 °C, p = 0.001; 37.1 ± 0.1 °C, p = 0.013; 36.9 ± 0.1 °C, respectively). Whole-body oxygen consumption was also significantly higher in hot and cold compared with room temperature (0.38 ± 0.01 L·min−1, p < 0.001; 0.52 ± 0.03 L·min−1, p < 0.001; 0.35 ± 0.01 L·min−1, respectively). In conclusion, these data show that acute temperature exposure alone does not elicit significant changes in skeletal muscle gene expression. When considered in conjunction with previous research, exercise appears to be a necessary component to observe gene expression alterations between different environmental temperatures in humans.

scholarly journals Heterogeneous muscle gene expression patterns in patients with massive rotator cuff tears

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0190439 ◽  
Author(s):  
Michael C. Gibbons ◽  
Kathleen M. Fisch ◽  
Rajeswari Pichika ◽  
Timothy Cheng ◽  
Adam J. Engler ◽  
...  
Keyword(s):  
Gene Expression ◽  
Rotator Cuff ◽  
Expression Patterns ◽  
Rotator Cuff Tears ◽  
Gene Expression Patterns ◽  
Muscle Gene Expression ◽  
Massive Rotator Cuff Tears ◽  
Muscle Gene

scholarly journals Longitudinal muscle gene expression patterns associated with differential intramuscular fat in cattle

animal ◽  
2015 ◽  
Vol 9 (4) ◽  
pp. 650-659 ◽  
Author(s):  
N.J. Hudson ◽  
A. Reverter ◽  
P.L. Greenwood ◽  
B. Guo ◽  
L.M. Cafe ◽  
...  
Keyword(s):  
Gene Expression ◽  
Longitudinal Muscle ◽  
Expression Patterns ◽  
Intramuscular Fat ◽  
Gene Expression Patterns ◽  
Muscle Gene Expression ◽  
Muscle Gene
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