Toxicity assessment and comparison of the land snail's Cornu aspersum responses against CuO nanoparticles and ZnO nanoparticles

Author(s):  
Konstantinos Feidantsis ◽  
Stavros Kalogiannis ◽  
Angela Marinoni ◽  
Areti-Maria Vasilogianni ◽  
Christina Gkanatsiou ◽  
...  
Author(s):  
Ying Shi ◽  
Alexander R. Pilozzi ◽  
Xudong Huang

Fe2O3, CuO and ZnO nanoparticles (NP) have found various industrial and biomedical applications. However, there are growing concerns among the general public and regulators about their potential environmental and health impacts as their physio-chemical interaction with biological systems and toxic responses of the latter are complex and not well understood. Herein we first reported that human SH-SY5Y and H4 cells and rat PC12 cell lines displayed concentration-dependent neurotoxic responses to insults of CuO nanoparticles (CuONP), but not to Fe2O3 nanoparticles (Fe2O3NP) or ZnO nanoparticles (ZnONP). This study provides evidence that CuONP induces neuronal cell apoptosis, discerns a likely p53-dependent apoptosis pathway and builds out the relationship between nanoparticles and Alzheimer’s disease (AD) through the involvement of reactive oxygen species (ROS) and increased Aβ levels in SH-SY5Y and H4 cells. Our results implicate that exposure to CuONP may be an environmental risk factor for AD. For public health concerns, regulation for environmental or occupational exposure of CuONP are thus warranted given AD has already become a pandemic.


Nanoscale ◽  
2018 ◽  
Vol 10 (46) ◽  
pp. 21985-21993 ◽  
Author(s):  
Jaanus Burk ◽  
Lauri Sikk ◽  
Peeter Burk ◽  
Bella B. Manshian ◽  
Stefaan J. Soenen ◽  
...  

Toxicity and cancer-killing potency of Fe-doped ZnO nanoparticles can be reliably modelled using atomistic nanodescriptors.


2021 ◽  
pp. 511-552
Author(s):  
Ankush Agrawal ◽  
Ankita Sharma ◽  
Garima Awasthi ◽  
Kamakshi ◽  
Anjali Awasthi ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6318
Author(s):  
Thi-Na Ta ◽  
Shin-Yuh Chern ◽  
Jeng-Haur Horng

This research aims to formulate a new lubricant containing oxide nanoparticles for enhancing anti-wear ability and reducing friction. Different concentrations of copper oxide (CuO) and zinc oxide (ZnO) nanoparticles were separately added to an ionic liquid, methyltrioctylammonium bis(trifluoromethylsulfonyl)imide [N1888] [NTf2], to formulate the tested lubricants. The tribological properties of the lubricants were tested by performing ball-on-disc wear tests on a tribotester (MTM, PCS Instruments). The results show that both the CuO and ZnO nanoparticles can increase the friction reduction ability of the ionic liquid when used as a neat lubricant. The anti-wear characteristic of the ionic liquid is increased by adding ZnO nanoparticles but decreased by adding CuO nanoparticles. The best tribological performance observed for the concentration of 0.2 wt% ZnO, with the wear scar diameter is reduced by 32% compared to the pure ionic liquid. The results of SEM/EDX analysis on the worm morphologies show different lubrication mechanisms of the nanoparticles in the [N1888] [NTf2], which are tribo-sintering for CuO nanoparticles, and third body with pure rolling effect for ZnO nanoparticles.


ENTOMON ◽  
2020 ◽  
Vol 44 (4) ◽  
pp. 293-300
Author(s):  
V.S. Salini

Investigation to evaluate the toxicity of carbofuran pesticides on haematological parameters of third instar larvae of Oryctes rhinoceros L. Indicated alterations in total haemocyte count and differential haemocyte count for toxicity assessment. Various doses of carbofuran (0.05g, 0.010g and 0.015 g) applied on insect through oral route and its impact after 24 hours of its application revealed that various doses of carbofuran exert specific alterations in both total and differential haemocytes of insect haemolymph.


Sign in / Sign up

Export Citation Format

Share Document