scholarly journals Outcome of preterm neonates born to women of a developing country at risk of preterm birth exposed to varying doses of antenatal corticosteroid: A prospective observational study

2020 ◽  
Vol 8 (2) ◽  
pp. 623-627
Author(s):  
Supriya ◽  
S.N. Singh ◽  
Shalini Tripathi ◽  
Mala Kumar
2017 ◽  
Vol 4 (3) ◽  
pp. 956
Author(s):  
Joy Christ H. ◽  
Praveen B. K.

Background: Respiratory distress syndrome (RDS) is the most common complication observed in preterm neonates. It has been observed in many studies done till date that neonates born to mothers who have received antenatal corticosteroids (ACS) have shown significantly lesser incidence in developing RDS as compared to neonates born to mothers who have not received ACS. The aim of the present study is to observe and compare the outcome of the neonates born to the mothers who have received and not received ACS between 24 weeks + 0 days to 36 weeks + 6 days of gestation.Methods: This was a hospital based prospective observational study, consisting of 201 neonates born to the mothers who have received and not received ACS between 24 weeks + 0 days and 36 weeks + 6 days of gestation. The outcome of neonates was observed and the data was analyzed by using frequency percentage and pearson’s chi square test.Results: Two hundred and one neonates were included in our study. It was concluded that the need of surfactant (P=0.004), CPAP (P=0.001) was significantly less and the rate of survival (P=0.000) was better in babies born to mothers who have received ACS in comparison to neonates born to mothers who have not received ACS. Conclusions: It was observed that in neonates there was significantly lesser incidence of respiratory distress syndrome, use of surfactant, CPAP, ventilation and number of deaths. But there was no significant statistical difference in incidence of necrotizing enterocolitis, sepsis, and PDA as compared to neonates born to mothers who have not received ACS. Hence it will require further study and analysis in a larger population. 


2020 ◽  
Vol 11 ◽  
pp. 290
Author(s):  
Toyin Ayofe Oyemolade ◽  
Amos Olufemi Adeleye ◽  
Oluwakemi C. Ogunyileka ◽  
Folawemimo M. Arogundade ◽  
Ayodele J. Olusola ◽  
...  

Background: In low-resource regions of the world, discharge against medical advice (DAMA) is one empiric contributory factor to poor in-hospital outcome that is not often mentioned. This study aims to investigate the determinants of DAMA from a rural neurosurgical service in a developing country. Methods: This was a prospective observational study of all patients who discharged against medical advice in our service between November 2018 and October 2019. Results: There were 88 patients, 67 (76.1%) males, in the study, (M:F = 3.2:1), representing 17.4% of our patient population in the study period. The peak incidence was in the 20–29 years age group which accounted for 37.5% of the cases. About 55% of the patients presented directly to our center; 31.8% were referred from other hospitals, while 3.4% came from traditional caregivers and 1.1% from religious homes. Head injury was the most common indication for presentation (76.1% of the cases). The duration of hospital stay ranged from 2 h to 14 days. Majority of the patients (87.5%) left the hospital within 8 h of presentation. The reason for DAMA was financial constraints in 50% of cases, inadequate health literacy in 20.5%, financial constraints and poor health literacy together in 12.5%, religious misgivings in 4.5%, and traditional belief in 2.3%. Neurotrauma was predictive of early DAMA (P = 0.001). Conclusion: The rate of DAMA was high in our study. Financial constraints with other socioeconomic limitations were the most common causes of DAMA in our environment.


2010 ◽  
Vol 117 (8) ◽  
pp. 963-967 ◽  
Author(s):  
R Mahony ◽  
A McKeating ◽  
T Murphy ◽  
F McAuliffe ◽  
C O’Herlihy ◽  
...  

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