Synergistic effects of citric acid - sodium alginate on physicochemical properties of α-tricalcium phosphate bone cement

2019 ◽  
Vol 45 (2) ◽  
pp. 2146-2152 ◽  
Author(s):  
Haishan Shi ◽  
Wenqian Zhang ◽  
Xu Liu ◽  
Shenghui Zeng ◽  
Tao Yu ◽  
...  
2015 ◽  
Vol 10 (3) ◽  
pp. 282-290 ◽  
Author(s):  
Shu-Hsien Huang ◽  
Yi-Jyun Chen ◽  
Chia-Tze Kao ◽  
Chi-Chang Lin ◽  
Tsui-Hsien Huang ◽  
...  

2020 ◽  
Author(s):  
Changtian Gong ◽  
Shuo Fang ◽  
Kezhou Xia ◽  
Jingteng Chen ◽  
Liangyu Guo ◽  
...  

Abstract Incorporating bioactive substances into synthetic bioceramic scaffolds is challenging. In this work, oxygen-carboxymethyl chitosan (O-CMC), a natural biopolymer that is nontoxic, biodegradable and biocompatible, was introduced into magnesium potassium phosphate cement (K-struvite) to enhance its mechanical properties and cytocompatibility. This study aimed to develop O-CMC/magnesium potassium phosphate composite bone cement (OMPC), thereby combining the optimum bioactivity of O-CMC with the extraordinary self-setting properties and mechanical intensity of the K-struvite. Our results indicated that O-CMC incorporation increased the compressive strength and setting time of K-struvite and decreased its porosity and pH value. Furthermore, OMPC scaffolds remarkably improved the proliferation, adhesion and osteogenesis related differentiation of MC3T3-E1 cells. Therefore, O-CMC introduced suitable physicochemical properties to K-struvite and enhanced its cytocompatibility for use in bone regeneration.


2021 ◽  
pp. 118269
Author(s):  
Yueshan Li ◽  
Zhisen Wang ◽  
Xiaoyu Wang ◽  
Bin Yan ◽  
Yinjie Peng ◽  
...  

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