scholarly journals Enhancing the mechanical properties and cytocompatibility of magnesium potassium phosphate cement by incorporating oxygen-carboxymethyl chitosan

2020 ◽  
Author(s):  
Changtian Gong ◽  
Shuo Fang ◽  
Kezhou Xia ◽  
Jingteng Chen ◽  
Liangyu Guo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Physicochemical Properties ◽  
Bone Cement ◽  
Ph Value ◽  
Setting Time ◽  
Potassium Phosphate ◽  
Carboxymethyl Chitosan ◽  
Bioactive Substances ◽  
Magnesium Potassium Phosphate Cement

Abstract Incorporating bioactive substances into synthetic bioceramic scaffolds is challenging. In this work, oxygen-carboxymethyl chitosan (O-CMC), a natural biopolymer that is nontoxic, biodegradable and biocompatible, was introduced into magnesium potassium phosphate cement (K-struvite) to enhance its mechanical properties and cytocompatibility. This study aimed to develop O-CMC/magnesium potassium phosphate composite bone cement (OMPC), thereby combining the optimum bioactivity of O-CMC with the extraordinary self-setting properties and mechanical intensity of the K-struvite. Our results indicated that O-CMC incorporation increased the compressive strength and setting time of K-struvite and decreased its porosity and pH value. Furthermore, OMPC scaffolds remarkably improved the proliferation, adhesion and osteogenesis related differentiation of MC3T3-E1 cells. Therefore, O-CMC introduced suitable physicochemical properties to K-struvite and enhanced its cytocompatibility for use in bone regeneration.

scholarly journals Effect of Waste Glass on the Properties and Microstructure of Magnesium Potassium Phosphate Cement

Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 2073
Author(s):  
Qiubai Deng ◽  
Zhenyu Lai ◽  
Rui Xiao ◽  
Jie Wu ◽  
Mengliang Liu ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Glass Powder ◽  
Setting Time ◽  
Potassium Phosphate ◽  
Heat Of Hydration ◽  
Waste Glass ◽  
Hydration Heat ◽  
Magnesium Potassium Phosphate Cement ◽  
The Matrix ◽  
Powder Content

Waste glass is a bulk solid waste, and its utilization is of great consequence for environmental protection; the application of waste glass to magnesium phosphate cement can also play a prominent role in its recycling. The purpose of this study is to evaluate the effect of glass powder (GP) on the mechanical and working properties of magnesium potassium phosphate cement (MKPC). Moreover, a 40mm × 40mm × 40mm mold was used in this experiment, the workability, setting time, strength, hydration heat release, porosity, and microstructure of the specimens were evaluated. The results indicated that the addition of glass powder prolonged the setting time of MKPC, reduced the workability of the matrix, and effectively lowered the hydration heat of the MKPC. Compared to an M/P ratio (MgO/KH2PO4 mass ratio) of 1:1, the workability of the MKPC with M/P ratios of 2:1 and 3:1 was reduced by 1% and 2.1%, respectively, and the peak hydration temperatures were reduced by 0.5% and 14.6%, respectively. The compressive strength of MKPC increased with an increase in the glass powder content at the M/P ratio of 1:1, and the addition of glass powder reduced the porosity of the matrix, effectively increased the yield of struvite-K, and affected the morphology of the hydration products. With an increase in the M/P ratio, the struvite-K content decreased, many tiny pores were more prevalent on the surface of the matrix, and the bonding integrity between the MKPC was weakened, thereby reducing the compressive strength of the matrix. At less than 40 wt.% glass powder content, the performance of MKPC improved at an M/P ratio of 1:1. In general, the addition of glass powders improved the mechanical properties of MKPC and reduced the heat of hydration.

Study on Physicochemical Properties of the Carbonated Hydroxyapatite Bone Cement

2007 ◽  
Vol 280-283 ◽  
pp. 1545-1548
Author(s):  
Li Min Dong ◽  
Chen Wang ◽  
Jie Mo Tian ◽  
Jian Pan ◽  
Qing Feng Zan
Keyword(s):  
Compressive Strength ◽  
Phase Composition ◽  
Physicochemical Properties ◽  
Bone Cement ◽  
Pore Size ◽  
Setting Time ◽  
Mineral Phase ◽  
Carbonated Hydroxyapatite ◽  
Natural Bone ◽  
Ft Ir

Carbonated hydroxyapatite (CHA) bone cement is capable of self-setting and has the component similar to the mineral phase of natural bone. But it is compact in structure and short of cavity, which limits new bone growing into CHA bone cement. In this paper, the foaming method was adopted to prepare the porous CHA. The setting time, compressive strength, porosity and pore size of the CHA were examined. The phase composition of the CHA was tested with XRD and FT-IR. The microstructure of the CHA was observed with SEM. The results show that setting time of 7~19 minutes, compressive strength of 26~32MPa, pore size of 100~200µm, porosity of 50~60%.

Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement

2007 ◽  
Vol 336-338 ◽  
pp. 1654-1657
Author(s):  
Rui Liu ◽  
Li Min Dong ◽  
Qing Feng Zan ◽  
Chen Wang ◽  
Jie Mo Tian
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Chemical Properties ◽  
Phase Evolution ◽  
Chitosan Microspheres ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement

The aim of this work is to improve the mechanical properties of calcium phosphate bone cement (CPC) by appending chitosan microspheres to CPC base. That chitosan degrades rapidly than bone cement has been proved by previous investigations. Porous CPC has low compressive strength because of the pores in it weakening the structure. Additive chitosan microspheres can improve the mechanical properties by bearing the compress with the CPC base and produce pores after degradation. This study investigates the effect of chitosan microspheres on the setting time, mechanical properties, phase evolution and morphology of CPC. The additive proportion of chitosan microspheres ranges from 0 wt% to 30 wt%. Compared with original CPC, the modified CPC has higher compressive strength, without significantly affecting the chemical properties. The phase composition of the CPC is tested by XRD. The microstructures of CPC are observed using SEM. The final setting times range from 5~15 minutes and can be modulated by using different liquid and powder (L/P) ratio.

Primary Study of an Injectable In Situ Composite of Collagen/Calcium Phosphate Porous Scaffold for Bone Substitute

2006 ◽  
Vol 309-311 ◽  
pp. 857-860 ◽  
Author(s):  
Q. Yao ◽  
Dong Xiao Li ◽  
K.W. Liu ◽  
Bo Zhang ◽  
H. Li ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Calcium Phosphate ◽  
Ph Value ◽  
Porous Scaffold ◽  
Setting Time ◽  
Primary Study ◽  
In Situ Composite ◽  
Setting Process ◽  
Main Material

This study was to develop an injectable biocompatible and porous calcium phosphate collagen composite cement scaffold by in situ setting. TTCP was prepared as main material of the CPC powder, and the collagen solution was added into the phosphoric acid directly to form the liquid phase. The injectable time (tI), setting time (tS) and setting temperature (TS), along with the PH value were recorded during the setting process. The compressive strength, morphology and porosity were tested. With the increase of collagen, this novel CPC get a tI of 5mins to 8mins, tS of 20mins to 30mins, compressive strength from 1.5MPa to 4MPa, and the porosity from 40% to 60%. This study gave a possibility to form a porous scaffold of collagen/CPC composite with the nature of injectability and setting in situ.

scholarly journals A Novel Fast-Setting Strontium-Containing Hydroxyapatite Bone Cement With a Simple Binary Powder System

2021 ◽  
Vol 9 ◽  
Author(s):  
Lijuan Sun ◽  
Tongyang Li ◽  
Sen Yu ◽  
Mengmeng Mao ◽  
Dagang Guo
Keyword(s):  
Compressive Strength ◽  
Bone Cement ◽  
Setting Time ◽  
Synthesis Temperature ◽  
Transformation Rate ◽  
Step Method ◽  
Cement Powder ◽  
Calcium Phosphate Bone Cement ◽  
One Step ◽  
Application Potential

In recent years, strontium-substituted calcium phosphate bone cement (Sr-CPC) has attracted more and more attentions in the field of bone tissue repair due to its comprehensive advantages of both traditional CPC and Sr ions. In this study, a crucial Sr-containing α-Ca3–xSrx(PO4)2 salt has been synthesized using a simplified one-step method at lower synthesis temperature. A novel Sr-CPC has been developed based on the simple binary Sr-containing α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder. The physicochemical properties and hydration mechanism of this Sr-CPC at various Sr contents were intensively investigated. The setting product of this Sr-CPC after a set for 72 h is a single-phase Sr-containing hydroxyapatite, and its compressive strength slightly decreased and its setting time extended with the increase of Sr content. The hydration process included the initial formation of the medium product CaHPO4⋅2H2O (30 min∼1 h), the following complete hydration of Ca4(PO4)2O and the initially formed CaHPO4⋅2H2O (2∼6 h), and the final self-setting of α-Ca3–xSrx(PO4)2 (6 h∼). The compressive strength of Sr-CPC, which was closely related to the transformation rate of Sr-containing hydroxyapatite, tended to increase with the extension of hydration time. In addition, Sr-CPC possessed favorable cytocompatibility and the effect of Sr ions on cytocompatibility of Sr-CPC was not obvious at low Sr contents. The present study suggests α-Ca3–xSrx(PO4)2 is a kind of vital Sr-containing salt source which is useful to develop some novel Sr-containing biomaterials. In addition, the new Sr-containing cement system based on this simple binary α-Ca3–xSrx(PO4)2/Ca4(PO4)2O cement powder displayed an attractive clinical application potential in orthopedics.

Effect of Metakaolin on Geopolymer Industry

2019 ◽  
pp. 49-70
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Flexural Strength ◽  
Reaction Mechanisms ◽  
Ordinary Portland Cement ◽  
Setting Time ◽  
Experimental Studies ◽  
Acid Attack ◽  
Repair Materials ◽  
Hardened State

This chapter discusses the effects of metakaolin (MK) on geopolymer mortar and concrete industries. The research topics of MK-based geopolymer cover reaction mechanisms and kinetics. This chapter aims at augmenting knowledge about enhancing mechanical properties of geopolymer mortars/concrete using MK. Specifically, this chapter presents literature studies as well as current experimental studies which delineate the effect of MK on fresh and hardened-state properties of geopolymer mortars (GPMs). Properties and characteristics of metakaolin are explained followed by properties of fresh MK mortars. Properties of hardened MK concrete and durability aspects of MK mortars are explained. Applications of MK-based geopolymers and metakaolin-based geopolymers as repair materials are also included in this chapter. The results of using MK-based GPMs revealed improved workability, enhanced setting time, increased density, higher compressive strength, flexural strength, and resistance against acid attack than conventional ordinary portland cement mortar/concrete.

scholarly journals Brushite cement containing gelatin: evaluation of mechanical strength and in vitro degradation

Cerâmica ◽  
2019 ◽  
Vol 65 (374) ◽  
pp. 261-266 ◽  
Author(s):  
L. P. Silva ◽  
M. D. P. Ribeiro ◽  
E. S. Trichês ◽  
M. Motisuke
Keyword(s):  
Mechanical Properties ◽  
Weight Loss ◽  
Compressive Strength ◽  
Solid Phase ◽  
Setting Time ◽  
Biological Properties ◽  
Solubility In Water ◽  
Ringer’S Solution ◽  
Weight Loss Data

Abstract Calcium phosphate cements (CPCs) are potential materials for repairing bone defects, mainly due to their excellent biocompatibility and osteoconductivity. Nevertheless, their low mechanical properties limit their usage in clinical applications. The gelatin addition may improve the mechanical and biological properties of CPCs, but their solubility in water may increase the porosity of the cement during degradation. Thus, the aim of this work was to investigate the influence of gelatin on the setting time, compressive strength and degradation rate of a brushite cement. CPCs were prepared with the addition of 0, 5, 10 and 20 wt% of gelatin powder in the solid phase of the cement. The results indicated that the setting time increased with gelatin. Furthermore, cement with 20 wt% of gelatin had an initial compressive strength of 14.1±1.8 MPa while cement without gelatin had 4.5±1.2 MPa. The weight loss, morphology and compressive strength were evaluated after degradation in Ringer’s solution. According to the weight loss data, gelatin was eliminated of samples during degradation. It was concluded that the presence of gelatin improved CPCs mechanical properties; however, as degradation in Ringer’s solution evolved, cement compressive strength decreased due to gelatin dissolution and, consequently, an increase in sample porosity.

scholarly journals A Quality Control Scheme for a Commercial Pozzolana Plant: A Case Study of Pozzolana Ghana Ltd

2019 ◽  
Vol 60 (2) ◽  
pp. 74-83
Author(s):  
J. Sarfo-Ansah ◽  
K. A. Boakye ◽  
E. Atiemo ◽  
R. Appiah
Keyword(s):  
Mechanical Properties ◽  
Quality Control ◽  
Compressive Strength ◽  
Process Control ◽  
Statistical Process Control ◽  
Setting Time ◽  
Mechanical Tests ◽  
Statistical Process ◽  
Control Scheme ◽  
Quality Control Scheme

A Quality control scheme was developed for a 200 ton per day commercial pozzolana plant. The scheme was evaluated for the first 34 days of production. Statistical Process Control tech­niques were specifically applied to the mechanical properties of setting times and compressive strength. Results obtained showed that pozzolana samples tested were chemically suitable with total SiO2, Al2O3 and Fe2O3 content ≥ 70%. Mechanical tests performed were mostly under control and when out-of-control, they gave valuable indication to plant malfunction or operator errors which were promptly corrected. The results of mechanical properties tested against the three major brands of cement on the Ghanaian market showed that pozzolana gave highest compressive strengths with Dangote CEM I 42.5R ranging between 21.3 MPa - 36.3 MPa at 7 days and 33.8 MPa - 45.1 MPa at 28 days whilst lowest compressive strengths were obtained with Ghacem CEM II B-L 32.5R cement ranging between 16.3 MPa – 23.6 MPa at 7 days and 23.3 MPa – 30.7 MPa at 28 days. Compressive strengths obtained with Diamond CEM II B-L 42.5N cement were average. A mean compressive strength for all brands of ce­ment of 25.2 MPa and 33.6 MPa at 7 days and 28 days respectively were obtained. Keywords: Pozzolana cement, statistical process control, Shewhart chart, compressive strength, setting time

Water Absorption and Mechanical Properties of Cements Based on Poly (Methyl Methacrylate) (PMMA) as Function of Hydroxyapatite (HA) Content

2008 ◽  
Vol 396-398 ◽  
pp. 493-496
Author(s):  
D. Ionita ◽  
G. Tihan ◽  
A.T. Marques
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Methyl Methacrylate ◽  
Water Absorption ◽  
Mechanical Characterization ◽  
Setting Time ◽  
Young Modulus ◽  
Point Of View ◽  
Maximum Strength ◽  
Poly Methyl Methacrylate

The purpose of this study is the obtaining of different orthopedic materials and chemical and mechanical characterization. The chemical tests used were setting time, water absorption and from the point of view of mechanical properties the Young modulus, compressive strength, and maximum strength. Also, the surface of orthopedic bioceramics materials was characterized by porosity test.

scholarly journals Effect of fly ash on physical and mechanical properties of mortar

2019 ◽  
Vol 17 (6) ◽  
pp. 35
Author(s):  
Vu-An Tran
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Fly Ash ◽  
Flexural Strength ◽  
Water Absorption ◽  
Thermal Power ◽  
Setting Time ◽  
Physical And Mechanical Properties ◽  
Flow Density ◽  
Control Specimen

This research investigates the physical and mechanical properties of mortar incorporating fly ash (FA), which is by-product of Duyen Hai thermal power plant. Six mixtures of mortar are produced with FA at level of 0%, 10%, 20%, 30%, 40%, and 50% (by volume) as cement replacement and at water-to-binder (W/B) of 0.5. The flow, density, compressive strength, flexural strength, and water absorption tests are made under relevant standard in this study. The results have shown that the higher FA content increases the flow of mortar but significantly decreases the density of mixtures. The water absorption and setting time increases as the samples incorporating FA. Compressive strength of specimen with 10% FA is approximately equal to control specimen at the 91-day age. The flexural strength of specimen ranges from 7.97 MPa to 8.94 MPa at the 91-day age with the best result for samples containing 10% and 20% FA.

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