scholarly journals The Relationship of the Oral Microbiotia to Periodontal Health and Disease

2011 ◽  
Vol 10 (4) ◽  
pp. 302-306 ◽  
Author(s):  
Michael A. Curtis ◽  
Camille Zenobia ◽  
Richard P. Darveau
Keyword(s):  
Periodontal Health ◽  
Health And Disease ◽  
Relationship Of ◽  
The Relationship

scholarly journals Maternal Prenatal Microbiome and Infant’s Immune System at the Origins of the Development of Health and Disease

2021 ◽  
Author(s):  
Iván Enrique Naranjo Logroño ◽  
Leslie Gricel Cuzco Macías ◽  
Alison Tamara Ruiz Chico ◽  
Anthony Alfonso Naranjo Coronel
Keyword(s):  
Immune System ◽  
Randomized Clinical Trials ◽  
Human Microbiome ◽  
First Year ◽  
El Sistema ◽  
Health And Disease ◽  
Land Surfaces ◽  
First Year Of Life ◽  
Relationship Of ◽  
The Relationship

Introduction: The human microbiome refers to the presence of microorganisms that live with its host. Objective: To analyze the relationship between the maternal perinatal microbiome and the development of the infant’s immune system, at the origins of the development of health and disease. Methodology: A non-systematic bibliographic review was carried out, including those controlled and randomized clinical trials focused on the relationship of the prenatal maternal microbiome and the infant’s immune system. And all those works whose approach was different from the topic raised were excluded. Discussion: 20 min after birth, the microbiome of newborns by vaginal delivery resembles the microbiota of their mother’s vagina, while those born by caesarean section house microbial communities that are usually found in human skin. The acquisition of the microbiome continues during the first years of life, with a microbiome of the baby’s gastrointestinal tract beginning to resemble that of an adult from the first year of life. Conclusion: Bacteria are microorganisms that have managed to colonize the vast majority of land surfaces, showing great adaptability. The human being is not indifferent, and hypotheses have been raised that affirm his participation in the development of health and the onset of the disease. Keywords: microbiota, inmune system, infant nutritional physiological phenomena. RESUMEN Introducción: El microbioma humano se refiere a la presencia de microorganismos que conviven con su hospedero. Objetivo: Analizar la relación existente entre el microbioma materno perinatal y el desarrollo del sistema inmune del lactante, en los orígenes del desarrollo de la salud y enfermedad. Metodología: Se realizó una revisión bibliográfica no sistemática, donde se incluyeron aquellos ensayos clínicos controlados y randomizados enfocados en la relación del microbioma materno prenatal y el sistema inmune del lactante. Y se excluyeron todos aquellos trabajos cuyo enfoque fue diferente al tema planteado. Resultados: Se encontraron 61 fuentes bibliográficas, de las cuales se incluyeron 53 artículos que contenían la información relacionada al tema y publicados en los últimos 11 años. Discusión: 20 min después del nacimiento, el microbioma de los recién nacidos por parto vaginal se asemeja a la microbiota de la vagina de su madre, mientras que los nacidos por cesárea albergan comunidades microbianas que generalmente se encuentran en la piel humana. La adquisición del microbioma continúa durante los primeros años de vida, con un el microbioma del tracto gastrointestinal del bebé comienza a parecerse al de un adulto desde el primer año de vida. Conclusiones: Las bacterias, son microorganismos que han logrado colonizar la gran mayoría de las superficies terrestres, mostrando una gran capacidad de adaptación. El ser humano, no es indiferente, y se han planteado hipótesis que aseveran su participación en el desarrollo de la salud e inicio de la enfermedad. Palabras clave: microbiota, sistema inmunológico, fenómenos fisiológicos nutricionales del lactante.

scholarly journals Radiographic assessment of the quality of dental restorations and their relationship with periodontal radiographic changes

2017 ◽  
Vol 32 (1) ◽  
pp. 17
Author(s):  
João Henrique Parise Fortes ◽  
Felipe Guarda Dallavilla ◽  
Camila Tirapelli ◽  
Plauto Christopher Aranha Watanabe ◽  
Ana Caroline Ramos Brito ◽  
...  
Keyword(s):  
Restorative Material ◽  
Radiographic Assessment ◽  
Periodontal Health ◽  
Panoramic Radiographs ◽  
Dental Restorations ◽  
Relationship Of ◽  
The Relationship ◽  
Radiographic Changes

INTRODUCION: The quality of dental restorations can be directly related to the maintenance of periodontal health. Particularly in relation to the contour of interproximal restorations, radiographs allow the assessment of possible excess or lack of proximal contact of restorative materials.OBJECTIVE: To evaluate the frequency of adequate and inadequate restorations, the type of restorative material and the relationship of these parameters with periodontal alterations.METHODS: One hundred digital panoramic radiographs were evaluated, with interproximal restorations being observed on these examinations, classifying them according to the material used and the quality of interproximal restoration and the presence of periodontal alterations. Thepossible correlation between these parameters was evaluated.RESULTS: The frequency of adequate restorations was 48% of restored proximal surfaces. Among the inadequate restorations, 46.2% and 53.8% were over-contour and lack of proximal contact, respectively. The restorations were metallic in 64% of cases.CONCLUSIONS: Over-contour were more common among metal restorations and lack of proximal contact was more frequent among non-metal restorations. The presence of restorations was associated with increased prevalence of periodontal alterations.

Psychoanalysis: From Degeneration to Regeneration

2020 ◽  
Author(s):  
Jean-Michel Rabaté
Keyword(s):  
Sigmund Freud ◽  
Death Drive ◽  
Scientific Psychology ◽  
Health And Disease ◽  
Italo Svevo ◽  
Relationship Of ◽  
The Relationship ◽  
Sabina Spielrein

This article explores the relationship of decadence and psychoanalysis in the work of four major figures: Max Nordau, Sabina Spielrein, Georg Groddeck, and Italo Svevo. Sigmund Freud and Nordau agreed on the need to launch a scientific psychology but disagreed on the relative function of disease and health in culture, the latter famously explored in Nordau’s Entartung (Degeneration; 1892–1893). Spielrein’s “Destruction as the Cause of Becoming” (1912) influenced Freud’s concept of the “death drive” while also examining the “decadent” interaction between Wagner and Nietzsche. Spielrein’s thinking, along with Otto Gross’s, influenced Georg Groddeck, from whom Freud derived the concept of the id. Groddeck’s psychoanalytical novel Der Seelensucher (The soulseeker; 1921) anticipates Svevo’s Zeno’s Conscience (1923) and Regeneration (1928), a comic play that meditates on health and disease and gives a final twist to a psychoanalytically inflected rethinking of the uses and abuses of the concept of decadence.

scholarly journals Oral Microbiome and Gingival Transcriptome Profiles of Ligature-Induced Periodontitis

2020 ◽  
Vol 99 (6) ◽  
pp. 746-757 ◽  
Author(s):  
J. Ebersole ◽  
S. Kirakodu ◽  
J. Chen ◽  
R. Nagarajan ◽  
O.A. Gonzalez
Keyword(s):  
Amplicon Sequencing ◽  
Young Group ◽  
Oral Microbiome ◽  
Specific Gene ◽  
Immune Genes ◽  
Gene Profiles ◽  
16S Amplicon Sequencing ◽  
Health And Disease ◽  
Relationship Of ◽  
The Relationship

This investigation evaluated the relationship of the oral microbiome and gingival transcriptome in health and periodontitis in nonhuman primates ( Macaca mulatta). Subgingival plaque samples and gingival biopsies were collected from healthy sites and at sites undergoing ligature-induced periodontitis. Microbial samples were analyzed with 16S amplicon sequencing to identify bacterial profiles in young (3 to 7 y) and adult (12 to 23 y) animals. The gingival transcriptome was determined with a microarray analysis and focused on the expression level of 452 genes that are associated with the development of inflammation and innate and adaptive immune responses. Of the 396 total operational taxonomic units (OTUs) identified across the samples, 81.8% were detected in the young group and 99.5% in the adult group. Nevertheless, 58 of the OTUs composed 88% of the signal in adults, and 49 OTUs covered 91% of the OTU readouts in the young group. Correlation analyses between the microbiome members and specific gingival genes showed a high number of significant bacteria-gene correlations in the young healthy tissues, which decreased by 75% in diseased tissues. In contrast, these correlations increased by 2.5-fold in diseased versus healthy tissues of adult animals. Complexes of bacteria were delineated that related to specific sets of immune genes, differing in health and disease and in the young versus adult animals. The correlated gene profiles demonstrated selected pathway overrepresentation related to particular bacterial complexes. These results provide novel insights into microbiome changes with disease and the relationship of these changes to specific gene profiles and likely biologic activities occurring in healthy and diseased gingival tissues in this human-like periodontitis model.

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