Unexpected effects of mobile phase solvents and additives on retention and resolution of N-acyl-D,L-leucine applying Cinchonane-based chiral ion exchangers

A simple , specific, accurate and precise RP-HPLC method was developed for determination of Irbesartan (IRB) in pharmaceutical dosage forms in tablets products and sachet using symmetry (L 1 ) column at 30°C . The signal was detected at 225 nm. A mobile phase dissolve 0.5 g of buffer potassium phosphate in 100 ml distilled water and adjust pH 2.7 , methanol and acetonitrile at ratio (40 :30 :30 ) . and flow rate 1.2ml/min -1 at pH=7.2 a mobile phase The percent recovery was detected 101 % and the linearity of concentration was 10-50 µg.ml -1 and supported this method by using (FT.I.R.) spectrum method for organic spectrophotometer to prove the chemical structure of this drug and some physical properties . we are obtained the result is identical of other literature . The proposed method was applied successfully for determination of the IRB in tablets products.

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EVALUATION OF NATURAL ION EXCHANGERS FOR THE REMOVAL OF RADIOACTIVE ISOTOPES FROM LIQUID EFFLUENTS

Environmental Engineering and Management Journal ◽

10.30638/eemj.2002.058 ◽

2002 ◽

Vol 1 (4) ◽

pp. 577-588

Author(s):

Eveline Popovici ◽

Igor Cretescu ◽

Elena Botezatu ◽

Gabriela Soreanu ◽

Alina Mihaela Hanu ◽

...

Keyword(s):

Radioactive Isotopes ◽

Ion Exchangers

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DEMINERALIZATION OF WATER WITH MIXED-LAYER ION-EXCHANGERS

Environmental Engineering and Management Journal ◽

10.30638/eemj.2013.016 ◽

2013 ◽

Vol 12 (1) ◽

pp. 137-145 ◽

Cited By ~ 2

Author(s):

Iuliana Rogoveanu Radosavlevici ◽

Dan Niculae Robescu

Keyword(s):

Mixed Layer ◽

Ion Exchangers

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QUANTITATIVE DETERMINATION OF CURCUMIN IN TURMERIC POWDER AND TURMERIC–HONEY BALL PILLS BY HPLC

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2018.4.6 ◽

2018 ◽

Vol 8 (4) ◽

pp. 42-47

Author(s):

Tien Nguyen Huu ◽

Tram Le Thi Bao ◽

Ngoc Nguyen Thi Nhu ◽

Thang Phan Phuoc ◽

Khan Nguyen Viet

Keyword(s):

Acetic Acid ◽

Gastric Mucosa ◽

Quantitative Determination ◽

Mobile Phase ◽

Curcuma Longa ◽

Biological Marker ◽

Hplc Method ◽

Chromatography Analysis ◽

Precision And Accuracy

Background: Curcumin is a major ingredient in turmeric (Curcuma longa L., Zingiberaceae), which has important activities such as anti-tumor, anti-inflammatory, antioxidant, anti-ischemia, protection of gastric mucosa etc,. Curcumin can be considered as a biological marker of turmeric and turmeric products. Objectives: Developing an HPLC method for quantification of curcumin in turmeric powder and turmeric - honey ball pills; applying this method for products on the market. Materials and methods: turmeric powder and turmeric - honey ball pills collected in Thua Thien Hue province. After optimization process, the method was validated and applied to evaluate the content of curcumin. Results: The chromatography analysis was performed with: Zorbaz Eclipse XDB-C18 (150 × 4.6 nm; 5 µm); Mobile phase: acetonitril: 2% acetic acid (45:55), Flow rate was kept constant at 1.0 ml/min; Detector PDA (420 nm). The method was validated for the HPLC system compatibility, specificity, linearity range, precision and accuracy; the recovery greater than 98%. Conclusion: The developed HPLC method can determine curcumin in turmeric powder and turmeric - honey ball pills. Key words: Curcumin, turmeric powder, turmeric-honey ball pills, quantitative determination, HPLC

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Faculty Opinions recommendation of Role of PDZK1 in membrane expression of renal brush border ion exchangers.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1027864.334836 ◽

2005 ◽

Author(s):

Mark Donowitz

Keyword(s):

Brush Border ◽

Ion Exchangers ◽

Membrane Expression ◽

Renal Brush Border

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Separation and Detection of Caffeine, Theophylline and Theobromine from Coffee Varieties, Carbonated Soft Drinks and Alcoholic Beverages

Revista de Chimie ◽

10.37358/rc.17.11.5959 ◽

2017 ◽

Vol 68 (11) ◽

pp. 2704-2707

Author(s):

Delia Nica Badea ◽

Codrina Levai

Keyword(s):

Food Safety ◽

Mobile Phase ◽

Soft Drinks ◽

Alcoholic Beverages ◽

Instrumental Method ◽

Spectral Library ◽

Active Components ◽

Carbonated Soft Drinks ◽

Mass Detector ◽

Methyl Xanthine

The paper evaluates the presence of methyl xanthine compounds: caffeine, theophylline, theobromine used as ingredients in carbonated soft drinks or as color and flavor ingredients in alcoholic beverages. The active components extracted from the selected products (coffee, tea, drinks) was separated and identified chromatographically using plates with silica nano -Sil NH2 / UV-254, mobile phase ethanol - water (50: 1, 50: 3, 50: 5; 50: 7; v / v) and 60 F254 plates, mobile phase acetone-toluene-chloroform (40:30:30 v / v). Separated caffeine and identified by TLC was analyzed using a HelWet Packard 5890 Gas Chromatograph equipped with MS 5972 mass detector and spectral library to confirm identification. This simple and rapid TLC, GC / MS instrumental method is useful in controlling traces of methyl xanthine compounds in food as a food safety measure.is useful in controlling traces compound of food products containing methylxanthines as a food safety measure.

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